GB752362A - Plasticized gelatin capsules - Google Patents

Plasticized gelatin capsules

Info

Publication number
GB752362A
GB752362A GB4930/54A GB493054A GB752362A GB 752362 A GB752362 A GB 752362A GB 4930/54 A GB4930/54 A GB 4930/54A GB 493054 A GB493054 A GB 493054A GB 752362 A GB752362 A GB 752362A
Authority
GB
United Kingdom
Prior art keywords
water
gelatin
soluble
substance
gelatin capsules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4930/54A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Catalent Pharma Solutions Inc
Original Assignee
Catalent Pharma Solutions Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Catalent Pharma Solutions Inc filed Critical Catalent Pharma Solutions Inc
Publication of GB752362A publication Critical patent/GB752362A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

In a plasticized gelatin capsule containing a water-soluble substance which normally attacks gelatin, the said substance is used in admixture with a water-soluble hygroscopic liquid vehicle containing 6-40 units of ethylene oxide per molecule, e.g. polyethylene glycols of mol. wt. 300-900, polyethylene glycol monolaurate or monooleates, polyoxyethylene (20) sorbitan monooleate; a weight ratio of 1-7 : 1 is suitable. Water may be added to the organic liquid. Water soluble substances encapsulated are, for example, chloral hydrate, choline chloride, sodium and potassium chloride and sulphate, ethanol, isopropanol, pentynols, betaine hydrochloride, methyl ethyl ketone, alkyl acetates of 2-4 carbon atoms. A gelatin-glycerine-water mixture is employed for forming the capsules, a method of capsulating being described. Specification 715,879 is referred to.
GB4930/54A 1953-11-09 1954-02-19 Plasticized gelatin capsules Expired GB752362A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US752362XA 1953-11-09 1953-11-09

Publications (1)

Publication Number Publication Date
GB752362A true GB752362A (en) 1956-07-11

Family

ID=22124407

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4930/54A Expired GB752362A (en) 1953-11-09 1954-02-19 Plasticized gelatin capsules

Country Status (1)

Country Link
GB (1) GB752362A (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2142824A (en) * 1983-07-07 1985-01-30 American Home Prod Pharmaceutical composition containing a liquid lubricant
US4892766A (en) * 1987-09-11 1990-01-09 Lilly Industries Limited Capsules
US4954346A (en) * 1988-06-08 1990-09-04 Ciba-Geigy Corporation Orally administrable nifedipine solution in a solid light resistant dosage form
US5037698A (en) * 1987-01-21 1991-08-06 Lilly Industries Limited Capsule filling employing hygroscopic components
WO2008072001A2 (en) * 2006-12-15 2008-06-19 Mw Encap Limited Hard shell capsule formulations
CN112451501A (en) * 2020-12-25 2021-03-09 北京达因高科儿童药物研究院有限公司 Soft capsule containing chloral hydrate and preparation method thereof

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2142824A (en) * 1983-07-07 1985-01-30 American Home Prod Pharmaceutical composition containing a liquid lubricant
US5037698A (en) * 1987-01-21 1991-08-06 Lilly Industries Limited Capsule filling employing hygroscopic components
US4892766A (en) * 1987-09-11 1990-01-09 Lilly Industries Limited Capsules
US4954346A (en) * 1988-06-08 1990-09-04 Ciba-Geigy Corporation Orally administrable nifedipine solution in a solid light resistant dosage form
WO2008072001A2 (en) * 2006-12-15 2008-06-19 Mw Encap Limited Hard shell capsule formulations
WO2008072001A3 (en) * 2006-12-15 2008-10-02 Mw Encap Ltd Hard shell capsule formulations
CN112451501A (en) * 2020-12-25 2021-03-09 北京达因高科儿童药物研究院有限公司 Soft capsule containing chloral hydrate and preparation method thereof

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