GB722885A - An anaesthetic substance - Google Patents
An anaesthetic substanceInfo
- Publication number
- GB722885A GB722885A GB7292/53A GB729253A GB722885A GB 722885 A GB722885 A GB 722885A GB 7292/53 A GB7292/53 A GB 7292/53A GB 729253 A GB729253 A GB 729253A GB 722885 A GB722885 A GB 722885A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydroxy
- acid
- aminobenzoic acid
- diethylaminoethanol
- aminobenzoic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention comprises the b -dimethylaminoethyl ester of 2-hydroxy-4-aminobenzoic acid and its inorganic acid salts. It may be prepared by esterifying 2-hydroxy-4-aminobenzoic acid with b -diethylaminoethanol in the presence of a concentrated inorganic acid or aryl sulphonic acid in amount sufficient to suppress any appreciable evolution of carbon dioxide through decomposition of the substituted benzoic acid. It may also be prepared by any of the esterification methods described in the Specification 722,795. In examples, (1) 2-hydroxy-4-aminobenzoic acid is esterified with diethylaminoethanol in the presence of a substantial amount of concentrated sulphuric acid; (2) 2-hydroxy-4-aminobenzoic acid is similarly esterified with ethylene chlorohydrin and the b -chloroethyl ester formed reacted with diethylamine in benzene; (3) anhydrous sodium 2-hydroxy-4-aminobenzoate is heated with 1-chloro-2-diethylamino-ethane in isopropyl alcohol; and (4) 2-hydroxy-4-aminobenzoic acid methyl ester is heated with diethylamino ethanol. Specification 588,032 is referred to.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE722885X | 1949-10-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB722885A true GB722885A (en) | 1955-02-02 |
Family
ID=6631908
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB7292/53A Expired GB722885A (en) | 1949-10-22 | 1950-10-23 | An anaesthetic substance |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB722885A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3029274A (en) * | 1949-10-22 | 1962-04-10 | Rheinpreussen Ag | Alkamine esters of amino salicylic acid |
-
1950
- 1950-10-23 GB GB7292/53A patent/GB722885A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3029274A (en) * | 1949-10-22 | 1962-04-10 | Rheinpreussen Ag | Alkamine esters of amino salicylic acid |
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