GB703878A - Improvements in or relating to light protection ointments - Google Patents
Improvements in or relating to light protection ointmentsInfo
- Publication number
- GB703878A GB703878A GB24445/51A GB2444551A GB703878A GB 703878 A GB703878 A GB 703878A GB 24445/51 A GB24445/51 A GB 24445/51A GB 2444551 A GB2444551 A GB 2444551A GB 703878 A GB703878 A GB 703878A
- Authority
- GB
- United Kingdom
- Prior art keywords
- benzyl
- pyridyl
- bromo
- ethylene diamine
- benzyl bromide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
N-(p-bromobenzyl) N-a -pyridyl N1 N1-dimethyl ethylene diamine is prepared by the method disclosed by Huttner et al Journal Amer. Chem. Soc. 68 (1946), 1999 using p-bromo-benzyl bromide in place of benzyl bromide. The o-bromo benzyl derivative is prepared in a similar manner.ALSO:An ointment for protecting the skin from the harmful constituents of sunlight and artificial light has as ultra-violet protective substance a benzyl-a-pyridyl-dimethyl-ethylene diamine halogenated in the benzyl radical, and/or a salt thereof. The preferred antihistamine is N-p-bromo-benzyl N-a-pyridyl N1, N1-dimethyl ethylene diamine. Specified salts are hydrochloride, sulphate, phosphate, perchlorate, thiocyanate, formate, maleate, cinnamate, salicylate, p-aminobenzoate and p-aminosalicylate. The efficacy of the preparation is increased by the last named salt, which may be replaced by p-aminosalicylic acid per se, or an alkali metal, alkali earth metal or organic base salt thereof. Opaque pigments such as ochre or alizarin madder may also be present. The example is of a solid oil-in-water emulsion containing in addition to the antihistamine, sodium p-aminosalicylate, adeps lanae, wax-like polyethylene oxides and eucerin anhydride (oxycholesterin bodies from wool grease in paraffin ointment) N-(p-bromobenzyl) N-a-pyridyl N1 N1-dimethyl ethylene diamine prepared according to Hutter et al. J. Amer. Chem. Soc. 68 (1946). 1999 using p-bromo-benzyl bromide in place of benzyl bromide (see Group IV (b)).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE703878X | 1950-10-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB703878A true GB703878A (en) | 1954-02-10 |
Family
ID=6615123
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB24445/51A Expired GB703878A (en) | 1950-10-20 | 1951-10-19 | Improvements in or relating to light protection ointments |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB703878A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2385685A1 (en) * | 1977-04-01 | 1978-10-27 | Mundipharma Ag | PROCESS FOR OBTAINING CERTAIN ESTERS OF AN AMINO-SALICYLIC ACID AND THEIR APPLICATION TO THE FILTRATION OF ULTRAVIOLET RAYS |
-
1951
- 1951-10-19 GB GB24445/51A patent/GB703878A/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2385685A1 (en) * | 1977-04-01 | 1978-10-27 | Mundipharma Ag | PROCESS FOR OBTAINING CERTAIN ESTERS OF AN AMINO-SALICYLIC ACID AND THEIR APPLICATION TO THE FILTRATION OF ULTRAVIOLET RAYS |
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