GB696886A - A method for irreversibly decolorizing streptomycin, salts of streptomycin, dihydrostreptomycin and the salts of dihydrostreptomycin - Google Patents
A method for irreversibly decolorizing streptomycin, salts of streptomycin, dihydrostreptomycin and the salts of dihydrostreptomycinInfo
- Publication number
- GB696886A GB696886A GB5170/50A GB517050A GB696886A GB 696886 A GB696886 A GB 696886A GB 5170/50 A GB5170/50 A GB 5170/50A GB 517050 A GB517050 A GB 517050A GB 696886 A GB696886 A GB 696886A
- Authority
- GB
- United Kingdom
- Prior art keywords
- dihydrostreptomycin
- streptomycin
- salts
- chlorine
- aqueous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/238—Cyclohexane rings substituted by two guanidine radicals, e.g. streptomycins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Streptomycin, salts of streptomycin, dihydrostreptomycin and salts of dihydrostreptomycin are irreversibly decolorized by treating a solution of a compound of said group under acidic conditions in a solvent medium with an oxidizing agent selected from chlorine, potassium permanganate, hydrogen peroxide and sodium dichromate until maximum decolorization is effected. The solutions are aqueous, aqueous alcoholic or alcoholic. The pH is 1.5 to 6.0, obtained by addition of a suitable acid or produced by bubbling the chlorine through a neutral solution. Preferably, methanolic solutions are treated at a pH below 3.5. In examples the oxidizing agents are (a) 5 per cent aqueous potassium permanganate, (b) 5 per cent aqueous sodium dichromate, (c) 30 per cent hydrogen peroxide and (d) chlorine. Specification 620,415 is referred to.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US696886XA | 1949-03-17 | 1949-03-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB696886A true GB696886A (en) | 1953-09-09 |
Family
ID=22090596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5170/50A Expired GB696886A (en) | 1949-03-17 | 1950-03-01 | A method for irreversibly decolorizing streptomycin, salts of streptomycin, dihydrostreptomycin and the salts of dihydrostreptomycin |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB696886A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2793974A (en) * | 1954-09-10 | 1957-05-28 | Wisconsin Alumni Res Found | Streptomycin composition and combatting plant pathogens therewith |
-
1950
- 1950-03-01 GB GB5170/50A patent/GB696886A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2793974A (en) * | 1954-09-10 | 1957-05-28 | Wisconsin Alumni Res Found | Streptomycin composition and combatting plant pathogens therewith |
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