GB689835A - Manufacture of para-aminosalicylates - Google Patents
Manufacture of para-aminosalicylatesInfo
- Publication number
- GB689835A GB689835A GB27281/49A GB2728149A GB689835A GB 689835 A GB689835 A GB 689835A GB 27281/49 A GB27281/49 A GB 27281/49A GB 2728149 A GB2728149 A GB 2728149A GB 689835 A GB689835 A GB 689835A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- group
- pyridyl
- phenyl
- salts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D233/24—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention relates to salts of p-aminosalicylic acid with anti-histamine bases having the general formula <FORM:0689835/IV (b)/1> or <FORM:0689835/IV (b)/2> in which R1 and R2 each represent a methyl group, or the group <FORM:0689835/IV (b)/3> represents a pyrrolidine group, and R3 represents a pyridyl or thiazolyl group. Examples are given of the preparation of the p-aminosalicylic acid salts of the following bases: 1 - phenyl - 1 - pyridyl - (21) - 3 - dimethylaminopropane; 1 - phenyl - 1 - pyridyl - (21)-3 - N - pyrrolidino - propane; 1 - phenyl - 1-thiazolyl - (21) - 3 - N - pyrrolidino - propane, and 10 - dimethylaminoethyl - phenthiazine. The salts are made by the interaction of the acid and base or by double decomposition of an alkali or alkaline earth salt of the acid with a salt of the base with an inorganic acid.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE293015X | 1949-09-05 | ||
CH290450T | 1950-08-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB689835A true GB689835A (en) | 1953-04-08 |
Family
ID=25733023
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB27281/49A Expired GB689835A (en) | 1949-09-05 | 1950-10-23 | Manufacture of para-aminosalicylates |
Country Status (3)
Country | Link |
---|---|
CH (2) | CH298055A (en) |
GB (1) | GB689835A (en) |
NL (1) | NL74271C (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2752345A (en) * | 1956-06-26 | Gentisic acid salts of aminoalkyl- | ||
US7230030B2 (en) | 1998-05-12 | 2007-06-12 | Schwarz Pharma Ag | Derivatives of 3,3-diphenylpropylamines |
US7989654B2 (en) | 2003-04-08 | 2011-08-02 | Ucb Pharma Gmbh | High purity bases of 3,3-diphenylpropylamino monoesters |
-
0
- NL NL74271D patent/NL74271C/xx active
-
1950
- 1950-08-01 CH CH298055D patent/CH298055A/en unknown
- 1950-08-01 CH CH293015D patent/CH293015A/en unknown
- 1950-10-23 GB GB27281/49A patent/GB689835A/en not_active Expired
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2752345A (en) * | 1956-06-26 | Gentisic acid salts of aminoalkyl- | ||
US7230030B2 (en) | 1998-05-12 | 2007-06-12 | Schwarz Pharma Ag | Derivatives of 3,3-diphenylpropylamines |
US7384980B2 (en) | 1998-05-12 | 2008-06-10 | Schwarz Pharma Ag | Derivatives of 3,3-diphenylpropylamines |
US7855230B2 (en) | 1998-05-12 | 2010-12-21 | Ucb Pharma Gmbh | Derivatives of 3,3-diphenylpropylamines |
US7985772B2 (en) | 1998-05-12 | 2011-07-26 | Ucb Pharma Gmbh | Derivatives of 3,3-diphenylpropylamines |
US8338478B2 (en) | 1998-05-12 | 2012-12-25 | Ucb Pharma Gmbh | Derivatives of 3,3-diphenylpropylamines |
US7989654B2 (en) | 2003-04-08 | 2011-08-02 | Ucb Pharma Gmbh | High purity bases of 3,3-diphenylpropylamino monoesters |
Also Published As
Publication number | Publication date |
---|---|
CH293015A (en) | 1953-08-31 |
CH298055A (en) | 1954-04-15 |
NL74271C (en) |
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