GB663903A - N-alkyl cinnamamides - Google Patents

N-alkyl cinnamamides

Info

Publication number
GB663903A
GB663903A GB2243549A GB2243549A GB663903A GB 663903 A GB663903 A GB 663903A GB 2243549 A GB2243549 A GB 2243549A GB 2243549 A GB2243549 A GB 2243549A GB 663903 A GB663903 A GB 663903A
Authority
GB
United Kingdom
Prior art keywords
butylamine
sec
reaction
alkyl
cinnamamides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2243549A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Parke Davis and Co LLC
Original Assignee
Parke Davis and Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parke Davis and Co LLC filed Critical Parke Davis and Co LLC
Priority to GB2243549A priority Critical patent/GB663903A/en
Publication of GB663903A publication Critical patent/GB663903A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

An N-alkylcinnamide of formula <FORM:0663903/IV (b)/1> where R is a branched chain alkyl group of 3 to 6 carbon atoms which is attached to the nitrogen atom through a carbon atom having not more than one valency satisfied by hydrogen, is prepared by the reaction of cinnamic acid, or a halide or ester thereof with an amine RNH2, or by the reaction of cinnamide with an alkyl halide RX where X is halogen. In the examples, cinnamoyl chloride is treated with (1) isopropylamine; (2) sec.-butylamine; (3) tert.-butylamine; and (4) sec.-amylamine to give the corresponding cinnamides.
GB2243549A 1949-08-29 1949-08-29 N-alkyl cinnamamides Expired GB663903A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB2243549A GB663903A (en) 1949-08-29 1949-08-29 N-alkyl cinnamamides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2243549A GB663903A (en) 1949-08-29 1949-08-29 N-alkyl cinnamamides

Publications (1)

Publication Number Publication Date
GB663903A true GB663903A (en) 1951-12-27

Family

ID=10179322

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2243549A Expired GB663903A (en) 1949-08-29 1949-08-29 N-alkyl cinnamamides

Country Status (1)

Country Link
GB (1) GB663903A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2987544A (en) * 1961-06-06 Tranquilizers
US3130227A (en) * 1959-08-27 1964-04-21 Chugai Pharmaceutical Co Ltd N-camphoryl-amino acetamides
US4190674A (en) 1976-02-03 1980-02-26 Burroughs Wellcome Co. 3-Fluoro-N-cyclopropylcinnamide
US4309444A (en) 1976-02-03 1982-01-05 Burroughs Wellcome Co. Biologically active amides

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2987544A (en) * 1961-06-06 Tranquilizers
US3130227A (en) * 1959-08-27 1964-04-21 Chugai Pharmaceutical Co Ltd N-camphoryl-amino acetamides
US4190674A (en) 1976-02-03 1980-02-26 Burroughs Wellcome Co. 3-Fluoro-N-cyclopropylcinnamide
US4309444A (en) 1976-02-03 1982-01-05 Burroughs Wellcome Co. Biologically active amides

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