GB481164A - Process for the manufacture of therapeutically valuable gold compounds - Google Patents
Process for the manufacture of therapeutically valuable gold compoundsInfo
- Publication number
- GB481164A GB481164A GB24247/36A GB2424736A GB481164A GB 481164 A GB481164 A GB 481164A GB 24247/36 A GB24247/36 A GB 24247/36A GB 2424736 A GB2424736 A GB 2424736A GB 481164 A GB481164 A GB 481164A
- Authority
- GB
- United Kingdom
- Prior art keywords
- solution
- alcohol
- suspension
- gold
- filtered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
- A61K38/014—Hydrolysed proteins; Derivatives thereof from animals from connective tissue peptides, e.g. gelatin, collagen
- A61K38/015—Hydrolysed proteins; Derivatives thereof from animals from connective tissue peptides, e.g. gelatin, collagen from keratin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Manufacture And Refinement Of Metals (AREA)
- Cosmetics (AREA)
Abstract
Alkaline earth metal salts of gold keratinates are prepared by treating the reaction products of gold salts and reduced or unreduced keratin hydrolysates with oxides, hydroxides or carbonates of alkaline earth metals. The products, which are water-soluble, possess therapeutic properties. The hydrolysis of the keratins may be effected with acids or alkalies and the reduction, if any, may take place simultaneously with or subsequently to the hydrolysis. Keratin degradation products p produced by enzymatic methods may also be employed. According to the examples: (1) hair is hydrolyzed with dilute hydrochloric acid and after neutralization with ammonia, auric chloride solution is added, the solution then made alkaline with caustic soda and poured into alcohol; an aqueous solution of the precipitated sodium gold keratinate is acidified, the filtered product suspended in water and shaken with a suspension of calcium hydroxide, filtered and poured into alcohol, whereupon the calcium salt separates out; (2) in the same manner as in (1), hair, horn or wool is hydrolyzed and from the sodium gold keratinate obtained the free acid is prepared; on shaking an aqueous suspension of the acid with strontium hydroxide or magnesium oxide in suspension and pouring the filtered solution into alcohol, the strontium magnesium salt respectively is precipitated; (3) horn is heated with dilute hydrochloric acid, tin added in portions and after neutralization with ammonia, hydrogen sulphide is passed in; to the filtrate auric chloride solution is added and after neutralization with caustic soda is poured into alcohol to precipitate the sodium gold keratinate; an aqueous solution of the latter is treated with hydrochloric acid, shaken with a suspension of magnesium carbonate and the filtered solution poured into alcohol, whereby the magnesium salt is precipitated. Specification 479,358 is referred to. Samples have been furnished under Sect. 2 (5) of calcium gold keratinates prepared by (1) following the procedure of (3) up to the addition of auric chloride solution and then rendering the solution alkaline by addition of a suspension of calcium hydroxide and pouring the filtrate into alcohol; (2) shaking the acidified solution of a sodium gold keratinate obtained in the process of (3) with a suspension of calcium carbonate and pouring the filtered solution into alcohol.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE481164X | 1935-09-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB481164A true GB481164A (en) | 1938-03-04 |
Family
ID=6542635
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB24247/36A Expired GB481164A (en) | 1935-09-13 | 1936-09-04 | Process for the manufacture of therapeutically valuable gold compounds |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB481164A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10245224B2 (en) | 2015-03-11 | 2019-04-02 | Patricio Alfredo Rodriguez Cerda | Topically applied cosmetic reductive composition containing keratin and sulphur |
-
1936
- 1936-09-04 GB GB24247/36A patent/GB481164A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10245224B2 (en) | 2015-03-11 | 2019-04-02 | Patricio Alfredo Rodriguez Cerda | Topically applied cosmetic reductive composition containing keratin and sulphur |
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