GB355574A - Process for the preparation of substances arresting blood-coagulation - Google Patents

Process for the preparation of substances arresting blood-coagulation

Info

Publication number
GB355574A
GB355574A GB31207/30A GB3120730A GB355574A GB 355574 A GB355574 A GB 355574A GB 31207/30 A GB31207/30 A GB 31207/30A GB 3120730 A GB3120730 A GB 3120730A GB 355574 A GB355574 A GB 355574A
Authority
GB
United Kingdom
Prior art keywords
polymerized
acid
alcohol
sodium hydroxide
coniferyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB31207/30A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB355574A publication Critical patent/GB355574A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Substances which arrest blood-coagulation are prepared by introducing salt-forming groups, such as CH2.COOH, SO3H, CH2.CH2.N(C2H5)2, into the polymerization products of propenylphenols and their derivatives by known methods. Examples are given of the preparation of (1) polymerized anethol-disulphonic acid by kneading polyanethol with concentrated sulphuric acid, (2) polymerized diethylaminoethylconiferyl alcohol by treating polymerized coniferyl alcohol with diethylaminoethyl bromide in the presence of sodium and alcohol, (3) polymerized coniferyl glycollic acid by heating polymerized coniferyl alcohol, obtained by alkaline hydrolysis of Siamese gum-benzoin, with chloracetic acid in the presence of aqueous sodium hydroxide. The Specification as open to inspection under Sect. 91 (3) (a) describes the introduction of saltforming groups into compounds of high molecular weight obtained by polymerization of aromatic starting materials, and contains two additional examples according to which (1) saliretin is treated with chloracetic acid in the presence of alcoholic sodium hydroxide to give polymerized saliretin glycollic acid, (2) phenol is condensed with formaldehyde in the presence of ammonia and the resulting resol heated with chloracetic acid in presence of sodium hydroxide whereby a resol glycollic acid is obtained. This subject-matter does not appear in the Specification as accepted.
GB31207/30A 1929-11-04 1930-10-17 Process for the preparation of substances arresting blood-coagulation Expired GB355574A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE355574X 1929-11-04

Publications (1)

Publication Number Publication Date
GB355574A true GB355574A (en) 1931-08-27

Family

ID=6290030

Family Applications (1)

Application Number Title Priority Date Filing Date
GB31207/30A Expired GB355574A (en) 1929-11-04 1930-10-17 Process for the preparation of substances arresting blood-coagulation

Country Status (1)

Country Link
GB (1) GB355574A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013116383A1 (en) * 2012-01-30 2013-08-08 Baxter International Inc. Non-anticoagulant sulfated or sulfonated synthetic polymers

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013116383A1 (en) * 2012-01-30 2013-08-08 Baxter International Inc. Non-anticoagulant sulfated or sulfonated synthetic polymers
JP2015504925A (en) * 2012-01-30 2015-02-16 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ Non-anticoagulant sulfated or sulfonated synthetic polymer
AU2013215167B2 (en) * 2012-01-30 2017-12-21 Baxalta GmbH Non-anticoagulant sulfated or sulfonated synthetic polymers
EP3607955A1 (en) * 2012-01-30 2020-02-12 Baxalta GmbH Non-anticoagulant sulfated or sulfonated synthetic polymers

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