GB348345A - Manufacture of n-methyl compounds of the pyridine series - Google Patents
Manufacture of n-methyl compounds of the pyridine seriesInfo
- Publication number
- GB348345A GB348345A GB12242/30A GB1224230A GB348345A GB 348345 A GB348345 A GB 348345A GB 12242/30 A GB12242/30 A GB 12242/30A GB 1224230 A GB1224230 A GB 1224230A GB 348345 A GB348345 A GB 348345A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methyl
- chloride
- pyridine
- employed
- quinolinium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
- C07D213/20—Quaternary compounds thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
Abstract
N-Methyl-pyridinium chlorides are prepared by interaction of methyl chloride with pyridine or a substitution product. Ordinary temperature may be employed, but preferably a raised temperature not exceeding 200 DEG C. The reaction may be effected under pressure and in the pressure of a chloride of copper or iron. A diluent may be employed, such as water, ether, benzene, benzine, tetra- and decahydronaphthalenes. The products are hydroscopic stable salts, which can readily be converted into for instance methylpyridones. Examples are given of the treatment of pyridine, a -picoline, b -methoxypyridine and a a -dichloropyridine with methyl chloride under various conditions. N-Methyl-quinolinium chlorides. The Specification as open to inspection under Sect. 91 (3) (a) states that the corresponding quinolinium compounds can similarly be obtained and includes an example for the preparation of N-methylquinolinium chloride from quinoline. Reference is also made to quinaldine as a starting material. This subject-matter does not appear in the Specification as accepted.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE348345X | 1929-04-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB348345A true GB348345A (en) | 1931-05-14 |
Family
ID=6257238
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB12242/30A Expired GB348345A (en) | 1929-04-19 | 1930-04-17 | Manufacture of n-methyl compounds of the pyridine series |
Country Status (3)
Country | Link |
---|---|
AT (1) | AT131118B (en) |
CH (1) | CH148112A (en) |
GB (1) | GB348345A (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5183869A (en) * | 1990-05-18 | 1993-02-02 | Ciba-Geigy Corporation | Hardenable compositions |
WO2009047291A2 (en) | 2007-10-12 | 2009-04-16 | Politechnika Lódzka | Use of quaternary pyridinium salts for inhibiting cancer metastases |
WO2018015862A1 (en) | 2016-07-18 | 2018-01-25 | Pharmena S.A. | 1-methylnicotinamide salts for use in raising the blood levels of adiponectin |
WO2018015861A1 (en) | 2016-07-18 | 2018-01-25 | Pharmena S.A. | 1-methylnicotinamide for the treatment of diseases associated with c-reactive protein |
WO2021205341A1 (en) | 2020-04-07 | 2021-10-14 | Pharmena S.A. | 1-methylnicotinamide for the prevention/treatment of inflammatory airway diseases |
-
1930
- 1930-03-22 AT AT131118D patent/AT131118B/en active
- 1930-04-01 CH CH148112D patent/CH148112A/en unknown
- 1930-04-17 GB GB12242/30A patent/GB348345A/en not_active Expired
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5183869A (en) * | 1990-05-18 | 1993-02-02 | Ciba-Geigy Corporation | Hardenable compositions |
WO2009047291A2 (en) | 2007-10-12 | 2009-04-16 | Politechnika Lódzka | Use of quaternary pyridinium salts for inhibiting cancer metastases |
WO2018015862A1 (en) | 2016-07-18 | 2018-01-25 | Pharmena S.A. | 1-methylnicotinamide salts for use in raising the blood levels of adiponectin |
WO2018015861A1 (en) | 2016-07-18 | 2018-01-25 | Pharmena S.A. | 1-methylnicotinamide for the treatment of diseases associated with c-reactive protein |
WO2021205341A1 (en) | 2020-04-07 | 2021-10-14 | Pharmena S.A. | 1-methylnicotinamide for the prevention/treatment of inflammatory airway diseases |
Also Published As
Publication number | Publication date |
---|---|
CH148112A (en) | 1931-07-15 |
AT131118B (en) | 1933-01-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB348345A (en) | Manufacture of n-methyl compounds of the pyridine series | |
GB1037122A (en) | Process for the production of 2-chloropyridine | |
GB364116A (en) | Manufacture of 1:4:5:8-naphthalene-tetra-carboxylic acid | |
GB306590A (en) | Process for the manufacture of ortho-aminoarylmercaptans | |
SU106597A1 (en) | Method for isolating 4-methylpyridine | |
US1855119A (en) | Process for the preparation of an alpha-chloro-pyridine | |
US2235570A (en) | Process for the manufacture of 1, 4, 5, 8-tetra-amino-anthraquinone | |
DE445890C (en) | Process for the production of black dyes | |
GB1037121A (en) | Process for the production of 2-bromopyridine | |
GB491163A (en) | A process for the manufacture of orthotolylbiguanide from orthotoluidine and dicyanodiamide | |
GB373440A (en) | Manufacture of ª‰-di(aryl-methyl)-aminoethanols | |
GB247188A (en) | A process for the production of 2-hydrazino-5-nitropyridine | |
GB702099A (en) | Improvements relating to the production of condensation products | |
GB916103A (en) | Process for the production of 2,4-dioxy-quinolines | |
GB426243A (en) | Manufacture of mixed carbonyl salicylic etheranhydride of salicylocarbonic acid and homologues thereof | |
GB464530A (en) | Manufacture of acid amides substituted at the nitrogen atom | |
GB370867A (en) | Improvements in the manufacture of cellulose ethers | |
GB236170A (en) | Improvements in and relating to processes for obtaining high percentage anthracene and carbazole from crude anthracene | |
ES474133A1 (en) | Process for the preparation of bis-triazolyl stilbenes. | |
GB672475A (en) | Bismuth salt of di-n-propyl acetic acid | |
GB811957A (en) | Improvements relating to 2-hydroxy-4-arylamino-quinolines | |
CA305457A (en) | Process of preparing n-methyl compounds of the pyridine series | |
GB478217A (en) | Process for the manufacture of hydrochloric acid and sodium sulphate | |
GB182084A (en) | Manufacture of 2-oxy-1-aryl-naphthylamines | |
GB370211A (en) | Process for the manufacture of alkyl halides |