GB2354823A - Device for identifying a trend indicative of an abnormal physiological condition - Google Patents
Device for identifying a trend indicative of an abnormal physiological condition Download PDFInfo
- Publication number
- GB2354823A GB2354823A GB9911985A GB9911985A GB2354823A GB 2354823 A GB2354823 A GB 2354823A GB 9911985 A GB9911985 A GB 9911985A GB 9911985 A GB9911985 A GB 9911985A GB 2354823 A GB2354823 A GB 2354823A
- Authority
- GB
- United Kingdom
- Prior art keywords
- physiological condition
- abnormal physiological
- measurements
- stored measurements
- identify
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
- A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
- A61B5/113—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb occurring during breathing
Abstract
A device comprising sensing means (2 to 12) for obtaining measurements of cardiac or pulmonary activity at successive instants in time, memory means (14) for storing said measurements and processing means (16) for identifying in said stored measurements any trend indicative of an abnormal physiological condition, for example cardiac or pulmonary failure due to sleep apnoea, and provide an early warning of such a physiological condition.
Description
2354823 Medical Device A number of devices are known for monitoring a
person's cardiac or pulmonary activity in order to detect the onset of an abnormal physiological condition such as sleep apnoea.
In a known device, a measured value is compared with a constant, predetermined value and an alarm triggered when the two values differ by more than an acceptable amount, thus indicating the existence of an abnormal physiological condition.
However, the device is unable to provide any warning prior to the onset of an abnormal physiological condition so that appropriate preventative action may be taken.
Furthermore, spurious isolated measurements may cause false triggering of the alarm.
We have now devised an arrangement which overcomes the limitations of existing devices.
In accordance with the present invention, there is provided a device comprising means for obtaining measurements of cardiac or pulmonary activity at successive instants in time, memory means for storing said measurements and processing means for identifying in said stored measurements any trend indicative of an abnormal physiological condition.
Preferably the processing means are arranged to identify in said stored measurements any progressive increase or decrease in the rate or magnitude of cardiac or pulmonary activity indicative of an impending abnormal physiological condition, for example cardiac or pulmonary failure due to sleep apnoea.
Preferably the processing means are also arranged to identify in said stored measurements any substantially constant deviation in the rate or magnitude of said cardiac or pulmonary activity from a preset value indicative of an existing abnormal physiological condition.
Preferably the processing means are arranged to identify a trend in the stored measurements indicative of an abnormal physiological condition by fitting an equation to the stored measurements. Most preferably a linear equation is 2 fitted to the stored measurements.
Preferably, a measure of the deviation of each of the stored measurements from the equation fitted thereto or from a mean value is used to estimate the likelihood of an existing or impending abnormal physiological condition being incorrectly identified.
Preferably the device comprises alarm means for providing an output signal when it is estimated from the fitted equation that within a predetermined period of time the magnitude or rate of cardiac or pulmonary activity will exceed a predetermined threshold value.
An embodiment of the present invention will now be described by way of an example only and with reference to the accompanying drawings, in which:
Figure 1 is a schematic diagram illustrating the hardware components of a device in accordance with the present invention; Figure 2 is a graph illustrating two potentially significant trends in measurements of cardiac or pulmonary activity; and Figure 3 is a graph illustrating a further two potentially significant types of trend in measurements of cardiac or pulmonary activity.
Referring to Figure 1 of the drawings, a device is shown for monitoring a person's cardiac and pulmonary activity.
A sensor 2, arranged to be attached to or placed in close proximity to a person, provides output signals in response to variations in pressure caused by the beating of the person's heart and by the person inhaling and exhaling.
Analogue output signals from the sensor 2 pass in-turn through an amplifier 4, low-pass filter 6 (to remove high frequency noise) and digital sampling means 8. A finite impulse response (FIR) digital bandpass filter 10 separates the digital signal into its cardiac and pulmonary components.
A first processing means 12 derives measurements from the respective signals, at successive instants of time, of the magnitude and rates of cardiac and pulmonary activity and stores these measurements in an electronic memory 14.
The stored measurements are subsequently processed by 3 a second processing means 16 to identify therein any trends which may indicate an abnormal physiological condition or the likelihood of such a condition arising.
The respective trends in each case take different forms. Firstly, as shown in Figure 2, a progressive increase or decrease in the rate and/or magnitude of cardiac and/or pulmonary activity may be indicative of an impending abnormal physiological condition. Secondly, as shown in Figure 3, a substantially constant deviation in the rate and/or magnitude of cardiac and/or pulmonary activity from respective preset values, whilst not necessarily indicative of an impending abnormal physiological condition, might nevertheless indicate an existing abnormal physiological condition.
The second processing means 16 are arranged to identify trends in the stored measurements indicative of an abnormal physiological condition by fitting respective lines to each set of stored measurements.
A fitted line of zero gradient, but displaced from a mean value by more than a predetermined amount, will be indicative of an existing abnormal physiological condition, whereas a fitted line of non-zero gradient will instead indicate the possibility of an abnormal physiological condition arising at some later time. In the latter case, the displacement of the fitted line from a predetermined mean value may be used by the second processing means to estimate the period of time remaining before a safe threshold level for a particular measurement will be exceeded. Where an abnormal physiological condition exists or is deemed imminent, an audible alarm 18 is sounded. 30 A measure of the deviation of each of the stored measurements from the line fitted thereto or from a mean value is used to estimate the likelihood of an abnormal physiological condition being incorrectly identified. The device is provided with a first interface 20 for communicating data to and from a personal computer 22 for display or analysis, a second interface 24 by which the device may be connected to a computer network e.g. the World Wide Web, for on-line monitoring of the person's cardiac and pulmonary activity, and built-in display means 26.
4 The built-in display means 26 and interfaces 20 and 24 may be used to provide a display of the raw signals acquired by the sensor 2, the output of the bandpass f ilter 10, the output of the first processing means 12 and/or various results 5 generated the second processing means 16.
The device thus described may be used to provide a reliable early warning of the possible onset of an abnormal physiological condition such as sleep apnoea.
Claims (26)
1 A device comprising means for obtaining measurements of cardiac or pulmonary activity at successive instants in time, memory means kor storing said measurements and processing means for identifying in said stored measurements any trend indicative of an abnormal physiological condition.
2) A device as claimed in Claim 1, wherein the processing means are arranged to identify in said stored measurements any progressive increase in the rate of cardiac activity indicative of an impending abnormal physiological condition.
3) A device as claimed in Claim 1, wherein the processing means are arranged to identify in said stored measurements any progressive increase in the rate of pulmonary activity indicative of an impending abnormal physiological condition.
4) A device as claimed in Claim 1, wherein the processing means are arranged to identify in said stored measurements any progressive increase in the magnitude of cardiac activity indicative of an impending abnormal physiological condition.
5) A device as claimed in Claim 1, wherein the processing means are arranged to identify in said stored measurements any progressive increase in the magnitude of pulmonary activity indicative of an impending abnormal physiological condition.
6) A device as claimed in Claim 1, wherein the processing means are arranged to identify in said stored measurements any progressive decrease in the rate of cardiac activity indicative of an impending abnormal physiological condition.
7) A device as claimed in Claim 1, wherein the processing 6 means are arranged to identify in said stored measurements any progressive decrease in the rate of pulmonary activity indicative of an impending abnormal physiological condition.
8) A device as claimed in Claim 1, wherein the processing 5 means are arranged to identify in said stored measurements any progressive decrease in the magnitude of cardiac activity indicative of an impending abnormal physiological condition.
9) A device as claimed in Claim 1, wherein the processing means are arranged to identify in said stored measurements any progressive decrease in the magnitude of pulmonary activity indicative of an impending abnormal physiological condition.
10) A device as claimed in Claim 2 or Claim 6, wherein the processing means are arranged to identify in said stored measurements any substantially constant deviation in the rate of said cardiac activity from a preset value indicative of an existing abnormal physiological condition.
11) A device as claimed in Claim 3 or Claim 7, wherein the processing means are arranged to identify in said stored measurements any substantially constant deviation in the rate of said pulmonary activity from a preset value indicative of an existing abnormal physiological condition.
12) A device as claimed in Claim 4 or Claim 8, wherein the processing means are arranged to identify in said stored. measurements any substantially constant deviation in the magnitude of said cardiac activity from a preset value indicative of an existing abnormal physiological condition.
13) A device as claimed in Claim 5 or Claim 9, wherein the processing means are arranged to identify in said stored 7 measurements any substantially constant deviation in the magnitude of said pulmonary activity from a preset value indicative of an existing abnormal physiological condition.
14) A device as claimed in any of Claims 10 to 13, wherein the processing means are arranged to identify a trend in the stored measurements indicative of an existing abnormal physiological condition by fitting an equation to the stored measurements.
15) A device as claimed in Claim 14, wherein a linear equation is fitted to the stored measurements.
16) A device as claimed in any of Claims 2 to 9, wherein the processing means are arranged to identify a trend in the stored measurements indicative of an impending abnormal physiological condition by fitting an equation to the stored measurements.
17) A device as claimed in Claim 16, wherein a linear equation is fitted to the stored measurements.
18) A device as claimed in Claim 14 or Claim 15, wherein a measure of the deviation of each of the stored measurements from the equation fitted thereto is used to estimate the likelihood of an existing abnormal physiological condition being incorrectly identified.
19) A device as claimed in Claim 16 or Claim 17, wherein a measure of the deviation of each of the stored measurements from the equation fitted thereto is used to estimate the likelihood of an impending abnormal physiological condition being incorrectly identified.
8 20) A device as claimed in any of Claims 2 to 9, wherein a measure of the deviation of each of the stored measurements f rom a mean value is used to estimate the likelihood of an existing abnormal physiological condition being incorrectly 5 identified.
21) A device as claimed in any of Claims 10 to 13, wherein a measure of the deviation of each of the stored measurements from a mean value is used to estimate the likelihood of an impending abnormal physiological condition being incorrectly 10 identified.
22) A device as claimed in Claim 16, as appended to Claim 4 or Claim 8, comprising alarm means for providing an output signal when it is estimated from the fitted equation that within a predetermined period of time the magnitude of cardiac 15 activity will exceed a predetermined threshold value.
23) A device as claimed in Claim 16, as appended to Claim 5 or Claim 9, comprising alarm means for providing an output signal when it is estimated from the fitted equation that within a predetermined period of time the magnitude of 20 pulmonary activity will exceed a predetermined threshold value.
24) A device as claimed in 16, as appended to Claim 2 or Claim 6, comprising alarm means for providing an output signal when it is estimated from the fitted equation that within a predetermined period of time the rate of cardiac activity will 25 exceed a predetermined threshold value.
25) A device as claimed in Claim 16, as appended to Claim 3 or Claim 7, comprising alarm means for providing an output signal when it is estimated from the fitted equation that within a predetermined period of time the rate of pulmonary 9 activity will exceed a predetermined threshold value.
26) A device substantially as herein described with reference to the accompanying drawings.
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9911985A GB2354823A (en) | 1999-05-25 | 1999-05-25 | Device for identifying a trend indicative of an abnormal physiological condition |
| PCT/GB2000/001976 WO2000071027A1 (en) | 1999-05-25 | 2000-05-23 | Medical device for measurements of cardiac or pulmonary activity |
| GB0127866A GB2365534A (en) | 1999-05-25 | 2000-05-23 | Medical device for measurements of cardiac or pulmonary activity |
| AU50866/00A AU5086600A (en) | 1999-05-25 | 2000-05-23 | Medical device for measurements of cardiac or pulmonary activity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9911985A GB2354823A (en) | 1999-05-25 | 1999-05-25 | Device for identifying a trend indicative of an abnormal physiological condition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB9911985D0 GB9911985D0 (en) | 1999-07-21 |
| GB2354823A true GB2354823A (en) | 2001-04-04 |
Family
ID=10853999
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB9911985A Withdrawn GB2354823A (en) | 1999-05-25 | 1999-05-25 | Device for identifying a trend indicative of an abnormal physiological condition |
| GB0127866A Withdrawn GB2365534A (en) | 1999-05-25 | 2000-05-23 | Medical device for measurements of cardiac or pulmonary activity |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB0127866A Withdrawn GB2365534A (en) | 1999-05-25 | 2000-05-23 | Medical device for measurements of cardiac or pulmonary activity |
Country Status (3)
| Country | Link |
|---|---|
| AU (1) | AU5086600A (en) |
| GB (2) | GB2354823A (en) |
| WO (1) | WO2000071027A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6783498B2 (en) * | 2002-03-26 | 2004-08-31 | Vivometrics, Inc. | Method and system for extracting cardiac parameters from plethysmographic signals |
| US8790272B2 (en) | 2002-03-26 | 2014-07-29 | Adidas Ag | Method and system for extracting cardiac parameters from plethysmographic signals |
| AU2004290588A1 (en) | 2003-11-18 | 2005-06-02 | Vivometrics, Inc. | Method and system for processing data from ambulatory physiological monitoring |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2214309A (en) * | 1987-12-26 | 1989-08-31 | Fukuda Denshi Kk | Display of electrocardiographic waveforms |
| US4899758A (en) * | 1986-01-31 | 1990-02-13 | Regents Of The University Of Minnesota | Method and apparatus for monitoring and diagnosing hypertension and congestive heart failure |
| GB2251490A (en) * | 1990-11-16 | 1992-07-08 | Atsunori Takara | Stress level measuring device |
| US5197480A (en) * | 1990-06-08 | 1993-03-30 | Vitatron Medical, B.V. | System and method for monitoring heart transplant rejection |
| GB2263170A (en) * | 1992-01-07 | 1993-07-14 | Fukuda Denshi Kk | Recording electrocardiogram information |
| GB2281780A (en) * | 1993-09-13 | 1995-03-15 | Hewlett Packard Co | Patient alarm detection using trend vector analysis |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4757825A (en) * | 1985-10-31 | 1988-07-19 | Diamond Research Group, Inc. | Cardio-pulmonary activity monitor |
| US5206807A (en) * | 1989-02-16 | 1993-04-27 | Air-Shields, Inc. | Neonatal cardiorespirograph incorporating multi-variable display and memory |
| US5479932A (en) * | 1993-08-16 | 1996-01-02 | Higgins; Joseph | Infant health monitoring system |
-
1999
- 1999-05-25 GB GB9911985A patent/GB2354823A/en not_active Withdrawn
-
2000
- 2000-05-23 AU AU50866/00A patent/AU5086600A/en not_active Abandoned
- 2000-05-23 WO PCT/GB2000/001976 patent/WO2000071027A1/en active Application Filing
- 2000-05-23 GB GB0127866A patent/GB2365534A/en not_active Withdrawn
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4899758A (en) * | 1986-01-31 | 1990-02-13 | Regents Of The University Of Minnesota | Method and apparatus for monitoring and diagnosing hypertension and congestive heart failure |
| GB2214309A (en) * | 1987-12-26 | 1989-08-31 | Fukuda Denshi Kk | Display of electrocardiographic waveforms |
| US5197480A (en) * | 1990-06-08 | 1993-03-30 | Vitatron Medical, B.V. | System and method for monitoring heart transplant rejection |
| GB2251490A (en) * | 1990-11-16 | 1992-07-08 | Atsunori Takara | Stress level measuring device |
| GB2263170A (en) * | 1992-01-07 | 1993-07-14 | Fukuda Denshi Kk | Recording electrocardiogram information |
| GB2281780A (en) * | 1993-09-13 | 1995-03-15 | Hewlett Packard Co | Patient alarm detection using trend vector analysis |
Also Published As
| Publication number | Publication date |
|---|---|
| AU5086600A (en) | 2000-12-12 |
| GB0127866D0 (en) | 2002-01-16 |
| WO2000071027A1 (en) | 2000-11-30 |
| GB2365534A (en) | 2002-02-20 |
| GB9911985D0 (en) | 1999-07-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| WAP | Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1) |