GB2235292B - Multiplex immunoassay system using distinguishable tagged ligands - Google Patents
Multiplex immunoassay system using distinguishable tagged ligandsInfo
- Publication number
- GB2235292B GB2235292B GB9016162A GB9016162A GB2235292B GB 2235292 B GB2235292 B GB 2235292B GB 9016162 A GB9016162 A GB 9016162A GB 9016162 A GB9016162 A GB 9016162A GB 2235292 B GB2235292 B GB 2235292B
- Authority
- GB
- United Kingdom
- Prior art keywords
- distinguishable
- immunoassay system
- multiplex immunoassay
- tagged ligands
- tagged
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39862189A | 1989-08-25 | 1989-08-25 |
Publications (3)
Publication Number | Publication Date |
---|---|
GB9016162D0 GB9016162D0 (en) | 1990-09-05 |
GB2235292A GB2235292A (en) | 1991-02-27 |
GB2235292B true GB2235292B (en) | 1993-09-22 |
Family
ID=23576097
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB9016162A Expired - Fee Related GB2235292B (en) | 1989-08-25 | 1990-07-24 | Multiplex immunoassay system using distinguishable tagged ligands |
Country Status (5)
Country | Link |
---|---|
JP (1) | JP2584530B2 (de) |
CA (1) | CA2021658C (de) |
DE (1) | DE4024350C2 (de) |
FR (1) | FR2651327B1 (de) |
GB (1) | GB2235292B (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2133643A1 (en) * | 1992-04-06 | 1993-10-14 | Stanley R. Bouma | Method and device for detection of nucleic acid or analyte using total internal reflectance |
AU2002221326A1 (en) * | 2000-12-11 | 2002-06-24 | Varian Australia Pty Ltd | Method and apparatus for analysis of multiplexed samples |
JP3429282B2 (ja) | 2001-02-02 | 2003-07-22 | リサーチ・インターナショナル・インコーポレーテッド | 自動化されたシステム、及びサンプルの分析方法 |
EP1735619A4 (de) * | 2004-04-01 | 2007-09-26 | Rules Based Medicine Inc | Universelle flintenprüfung |
US7496245B2 (en) | 2004-08-20 | 2009-02-24 | Research International, Inc. | Misalignment compensating optical sensor and method |
US7842465B2 (en) * | 2006-01-17 | 2010-11-30 | Palo Alto Research Center Incorporated | Immunocytostaining methods for enhanced dye ratio discrimination in rare event detection |
US7651869B2 (en) | 2006-03-14 | 2010-01-26 | Research International, Inc. | Optical assay apparatus and methods |
US7875433B2 (en) | 2007-02-26 | 2011-01-25 | Response Biomedical Corporation | Comparative multiple analyte assay |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3604927A (en) * | 1966-11-16 | 1971-09-14 | Block Engineering | Total reflection fluorescence spectroscopy |
US3652761A (en) * | 1969-09-04 | 1972-03-28 | Corning Glass Works | Immunochemical composites and antigen or antibody purification therewith |
DE2953610C1 (de) * | 1979-03-19 | 1985-04-11 | International Diagnostic Technology, Inc., Santa Clara, Calif. | Verfahren zum Bestimmen eines immunologisch aktiven Stoffs |
JPS5745454A (en) * | 1980-09-02 | 1982-03-15 | Fuji Photo Film Co Ltd | Immunochemical measuring method for various minor components |
JPS585659A (ja) * | 1981-06-24 | 1983-01-13 | ハイブリテツク インコ−ポレ−テツド | 単クロ−ン性抗体を使用する免疫学的、抑制試験 |
US4582809A (en) * | 1982-06-14 | 1986-04-15 | Myron J. Block | Apparatus including optical fiber for fluorescence immunoassay |
US4471058A (en) * | 1982-07-26 | 1984-09-11 | Board Of Trustees Operating Michigan State University | Method for the detection and/or determination of a polyvalent antigen using at least two different monoclonal antibodies |
US4447546A (en) * | 1982-08-23 | 1984-05-08 | Myron J. Block | Fluorescent immunoassay employing optical fiber in capillary tube |
US4584277A (en) * | 1983-04-05 | 1986-04-22 | Syntex (U.S.A.) Inc. | Fluorescent multiparameter particle analysis |
US4558014A (en) * | 1983-06-13 | 1985-12-10 | Myron J. Block | Assay apparatus and methods |
US4582791A (en) * | 1983-10-07 | 1986-04-15 | Syntex (U.S.A.) Inc. | Reducing non-specific background in immunofluorescence techniques |
US4595661A (en) * | 1983-11-18 | 1986-06-17 | Beckman Instruments, Inc. | Immunoassays and kits for use therein which include low affinity antibodies for reducing the hook effect |
JPH0789116B2 (ja) * | 1985-06-14 | 1995-09-27 | 帝人株式会社 | モノクローナル抗体を用いた免疫学的測定方法およびそのためのキット |
JPS6238362A (ja) * | 1985-08-12 | 1987-02-19 | Chemo Sero Therapeut Res Inst | Tshの測定方法 |
AU614935B2 (en) * | 1986-08-06 | 1991-09-19 | Multilyte Limited | Determination of analyte concentration using two labelling markers |
US4704891A (en) * | 1986-08-29 | 1987-11-10 | Becton, Dickinson And Company | Method and materials for calibrating flow cytometers and other analysis instruments |
GB8623494D0 (en) * | 1986-09-30 | 1986-11-05 | Mackay C D | Assay technique |
US4954435A (en) * | 1987-01-12 | 1990-09-04 | Becton, Dickinson And Company | Indirect colorimetric detection of an analyte in a sample using ratio of light signals |
JPH0827282B2 (ja) * | 1987-07-01 | 1996-03-21 | 帝人株式会社 | ヒト・プロテインcの免疫学的測定法,測定試薬およびそのキット |
GB2233450B (en) * | 1989-06-24 | 1993-06-30 | Univ Wales Medicine | Detecting or quantifing multiple analytes with luminescent reagents |
-
1990
- 1990-07-20 CA CA 2021658 patent/CA2021658C/en not_active Expired - Fee Related
- 1990-07-24 GB GB9016162A patent/GB2235292B/en not_active Expired - Fee Related
- 1990-07-27 DE DE19904024350 patent/DE4024350C2/de not_active Expired - Fee Related
- 1990-08-17 FR FR9010440A patent/FR2651327B1/fr not_active Expired - Fee Related
- 1990-08-24 JP JP2221447A patent/JP2584530B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2584530B2 (ja) | 1997-02-26 |
GB9016162D0 (en) | 1990-09-05 |
GB2235292A (en) | 1991-02-27 |
FR2651327A1 (fr) | 1991-03-01 |
CA2021658C (en) | 2001-10-09 |
DE4024350C2 (de) | 2000-03-16 |
FR2651327B1 (fr) | 1994-03-11 |
DE4024350A1 (de) | 1991-02-28 |
JPH03272466A (ja) | 1991-12-04 |
CA2021658A1 (en) | 1991-02-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
732E | Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977) | ||
PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 20070724 |