GB2125292B - Stable aqueous formulations of vinca alkaloids - Google Patents

Stable aqueous formulations of vinca alkaloids

Info

Publication number
GB2125292B
GB2125292B GB08319146A GB8319146A GB2125292B GB 2125292 B GB2125292 B GB 2125292B GB 08319146 A GB08319146 A GB 08319146A GB 8319146 A GB8319146 A GB 8319146A GB 2125292 B GB2125292 B GB 2125292B
Authority
GB
United Kingdom
Prior art keywords
vinca alkaloids
stable aqueous
aqueous formulations
formulations
stable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08319146A
Other versions
GB2125292A (en
GB8319146D0 (en
Inventor
Robert Lee Robison
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of GB8319146D0 publication Critical patent/GB8319146D0/en
Publication of GB2125292A publication Critical patent/GB2125292A/en
Application granted granted Critical
Publication of GB2125292B publication Critical patent/GB2125292B/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GB08319146A 1982-07-19 1983-07-15 Stable aqueous formulations of vinca alkaloids Expired GB2125292B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39965482A 1982-07-19 1982-07-19
US47607783A 1983-03-17 1983-03-17

Publications (3)

Publication Number Publication Date
GB8319146D0 GB8319146D0 (en) 1983-08-17
GB2125292A GB2125292A (en) 1984-03-07
GB2125292B true GB2125292B (en) 1986-06-04

Family

ID=27016716

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08319146A Expired GB2125292B (en) 1982-07-19 1983-07-15 Stable aqueous formulations of vinca alkaloids

Country Status (16)

Country Link
AU (1) AU553514B2 (en)
BE (1) BE897280A (en)
CH (1) CH654744A5 (en)
DE (1) DE3324964A1 (en)
FR (1) FR2531860B1 (en)
GB (1) GB2125292B (en)
HK (1) HK43087A (en)
HU (1) HU191538B (en)
IE (1) IE55388B1 (en)
IL (1) IL69203A (en)
IT (1) IT1170152B (en)
LU (1) LU84910A1 (en)
NL (1) NL184146C (en)
NZ (1) NZ204868A (en)
PH (1) PH19098A (en)
SE (1) SE463804B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU195513B (en) * 1984-10-16 1988-05-30 Richter Gedeon Vegyeszet Process for producing stable solutions of alkaloides with bis-indole skeleton
FR2597750B1 (en) * 1986-04-25 1989-06-02 Pf Medicament STABLE AQUEOUS SOLUTION OF VINCRISTINE SULFATE
FR2623089B1 (en) * 1987-11-13 1990-04-27 Pf Medicament PHARMACEUTICAL COMPOSITION FOR PARENTERAL ADMINISTRATION OF NAVELBINE
US4923876A (en) * 1988-04-18 1990-05-08 Cetus Corporation Vinca alkaloid pharmaceutical compositions
HU204995B (en) 1989-11-07 1992-03-30 Richter Gedeon Vegyeszet Process for producing pharmaceutical composition comprising alkaloid with bis-indole skeleton, with antitumour activity and suitable fr parenteral purposes
FR2910812B1 (en) * 2006-12-29 2009-03-20 Pierre Fabre Medicament Sa LYOPHILIZED INJECTABLE PHARMACEUTICAL COMPOSITIONS OF HEMI-SYNTHETIC STABLE VINCA ALKALOID DERIVATIVES AT AMBIENT TEMPERATURE
EP3328385B1 (en) * 2015-08-01 2020-07-08 Sun Pharmaceutical Industries Ltd Dosage form of vinca alkaloid drug

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3097137A (en) * 1960-05-19 1963-07-09 Canadian Patents Dev Vincaleukoblastine
US3749784A (en) * 1972-05-03 1973-07-31 Lilly Co Eli Psoriasis treatment
GB2020180B (en) * 1978-05-08 1982-08-25 Nelson Res & Dev Ophthalmic compositions containingcolchicine or vinblastinr
US4208414A (en) * 1978-06-05 1980-06-17 Eli Lilly And Company Vinblastine in rheumatoid arthritis
US4259242A (en) * 1978-10-10 1981-03-31 Eli Lilly And Company Method of preparing vindesine sulfate
HU181940B (en) * 1979-11-02 1983-11-28 Richter Gedeon Vegyeszet Process for producing solutions of vincane derivatives for parentheral application
OA06421A (en) * 1980-06-10 1981-09-30 Omnium Chimique Sa Process for the preparation of N- (vinblastinoyl-23) derivatives of amino acids and peptides.

Also Published As

Publication number Publication date
HK43087A (en) 1987-06-05
IL69203A0 (en) 1983-11-30
NL8302552A (en) 1984-02-16
AU1689183A (en) 1984-01-26
FR2531860B1 (en) 1986-09-26
SE8304009D0 (en) 1983-07-15
LU84910A1 (en) 1985-04-17
AU553514B2 (en) 1986-07-17
IT8321644A0 (en) 1983-06-15
IE831646L (en) 1984-01-19
NZ204868A (en) 1986-10-08
PH19098A (en) 1986-01-02
SE8304009L (en) 1984-01-20
BE897280A (en) 1984-01-13
IE55388B1 (en) 1990-08-29
NL184146B (en) 1988-12-01
IL69203A (en) 1986-03-31
HU191538B (en) 1987-03-30
GB2125292A (en) 1984-03-07
DE3324964A1 (en) 1984-01-19
IT1170152B (en) 1987-06-03
NL184146C (en) 1989-05-01
CH654744A5 (en) 1986-03-14
SE463804B (en) 1991-01-28
GB8319146D0 (en) 1983-08-17
FR2531860A1 (en) 1984-02-24
DE3324964C2 (en) 1991-03-14

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Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Effective date: 20030714