GB203402A - Improvements in centrifugal machines for the treatment of vaccine - Google Patents
Improvements in centrifugal machines for the treatment of vaccineInfo
- Publication number
- GB203402A GB203402A GB15945/22A GB1594522A GB203402A GB 203402 A GB203402 A GB 203402A GB 15945/22 A GB15945/22 A GB 15945/22A GB 1594522 A GB1594522 A GB 1594522A GB 203402 A GB203402 A GB 203402A
- Authority
- GB
- United Kingdom
- Prior art keywords
- rotor
- cuts
- chamber
- liquid
- flange
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 239000007788 liquid Substances 0.000 abstract 4
- 241000894006 Bacteria Species 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/06—Lysis of microorganisms
- C12N1/066—Lysis of microorganisms by physical methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Mycology (AREA)
- Centrifugal Separators (AREA)
Abstract
203,402. Thomson, D., and Macfie, R. F. June 8, 1922. Mixing-apparatus.-A centrifugal machine, for the treatment of vaccine, has two elements moving relatively to one another at a high speed, and provided with passages which during the move,- ment are brought into and out of register with one another, the liquid being forced through the passages and violently agitated so that the bacteria are crushed. The base 10 supports a bridgepiece 11 carrying the upper bearing for the spindle, and also has an annular projection 17 provided with a large number of saw-cuts 19 inclined to the radial, as shown in Fig. 2, and also inclined to the vertical. The spindle 14 in radial and thrust bearings carries a driving pulley 26 and a rotor 27. The rotor has an upstanding and overhanging flange 29 forming a chamber in the upper part of the rotor connected by a passage 33 to the space beneath the rotor bounded by the peripheral flange 31. This flange fits within the annular flange 17 and has a number of saw-cuts 32 inclined in the opposite direction to the radial and the vertical as compared with the cuts 19. A pipe 23 with an adjustable cock 25 connects the annular space 18 to the chamber in the rotor. The machine is set in motion and a quantity of liquid is introduced into the rotor. It passes through the passages 33, through the intermittent communication of the saw-cuts 32, 19 to the annular space 18 and then back to the rotor chamber by the pipe 23, so that a continuous circulation is maintained. In a modification, the part 20 extends inwards and upwards to form a chamber for liquid the pressure of which will balance the centrifugal force of liquid escaping between the rotor and stator.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB15945/22A GB203402A (en) | 1922-06-08 | 1922-06-08 | Improvements in centrifugal machines for the treatment of vaccine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB15945/22A GB203402A (en) | 1922-06-08 | 1922-06-08 | Improvements in centrifugal machines for the treatment of vaccine |
Publications (1)
Publication Number | Publication Date |
---|---|
GB203402A true GB203402A (en) | 1923-09-10 |
Family
ID=10068372
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB15945/22A Expired GB203402A (en) | 1922-06-08 | 1922-06-08 | Improvements in centrifugal machines for the treatment of vaccine |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB203402A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2652202A (en) * | 1948-02-27 | 1953-09-15 | American Viscose Corp | Homogenizing mill |
FR2939445A1 (en) * | 2008-12-10 | 2010-06-11 | Biomerieux Sa | AUTOMATED LYSE SYSTEM OF SAMPLE MICROORGANISMS, EXTRACTION AND PURIFICATION OF NUCLEIC ACIDS FROM MICROORGANISMS FOR ANALYSIS |
US10119114B2 (en) | 2007-06-07 | 2018-11-06 | Biomerieux | Device for the lysis of microorganisms present in an environmental or clinical sample and the extraction of nucleic acids from said microorganisms for analysis |
-
1922
- 1922-06-08 GB GB15945/22A patent/GB203402A/en not_active Expired
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2652202A (en) * | 1948-02-27 | 1953-09-15 | American Viscose Corp | Homogenizing mill |
US10119114B2 (en) | 2007-06-07 | 2018-11-06 | Biomerieux | Device for the lysis of microorganisms present in an environmental or clinical sample and the extraction of nucleic acids from said microorganisms for analysis |
FR2939445A1 (en) * | 2008-12-10 | 2010-06-11 | Biomerieux Sa | AUTOMATED LYSE SYSTEM OF SAMPLE MICROORGANISMS, EXTRACTION AND PURIFICATION OF NUCLEIC ACIDS FROM MICROORGANISMS FOR ANALYSIS |
WO2010067019A3 (en) * | 2008-12-10 | 2010-10-07 | bioMérieux | Automated system for the lysis of microorganisms in a sample, and for the extraction and purification of the nucleic acids of said microorganisms for analysis |
US8647858B2 (en) | 2008-12-10 | 2014-02-11 | Biomerieux | Automated system for the lysis of microorganisms present in a sample, for extraction and for purification of the nucleic acids of said microorganisms for purposes of analysis |
CN102245756B (en) * | 2008-12-10 | 2015-11-25 | 生物梅里埃公司 | For being present in microbial lytic in sample, for the Isolation and purification of the nucleic acid of described microorganism to carry out the automatic system analyzed |
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