GB2006196A - Phenylacetamides with analgesic activity - Google Patents
Phenylacetamides with analgesic activityInfo
- Publication number
- GB2006196A GB2006196A GB7838905A GB7838905A GB2006196A GB 2006196 A GB2006196 A GB 2006196A GB 7838905 A GB7838905 A GB 7838905A GB 7838905 A GB7838905 A GB 7838905A GB 2006196 A GB2006196 A GB 2006196A
- Authority
- GB
- United Kingdom
- Prior art keywords
- carbon atoms
- analgesic activity
- hydrogen atom
- different
- alkyl group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
A phenylacetamide compound of the general formula (I): <IMAGE> wherein each of R1 and R2, which are the same or different, represents an alkyl group having 1 to 3 carbon atoms or R1 and R2 together form a ring with the nitrogen atom to which they are attached; R3 represents a hydrogen atom or an alkyl group having 1 to 3 carbon atoms; X represents an alkoxy group having 1 to 3 carbon atoms; Y represents a hydrogen atom or an alkoxyl group having 1 to 3 carbon atoms; and each of n and m, which are the same or different, is 0, 1 or 2; or a pharmaceutically acceptable salt thereof, has a strong analgesic activity with very weak physical dependence liability, and which is useful as a therapeutically active agent for various types of pain.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11978077A JPS5455544A (en) | 1977-10-05 | 1977-10-05 | Pheylacetamide derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
GB2006196A true GB2006196A (en) | 1979-05-02 |
Family
ID=14770030
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB7838905A Withdrawn GB2006196A (en) | 1977-10-05 | 1978-10-02 | Phenylacetamides with analgesic activity |
Country Status (8)
Country | Link |
---|---|
JP (1) | JPS5455544A (en) |
BE (1) | BE870992A (en) |
DE (1) | DE2843328A1 (en) |
FR (1) | FR2405240A1 (en) |
GB (1) | GB2006196A (en) |
IT (1) | IT1106921B (en) |
NL (1) | NL7810053A (en) |
SE (1) | SE7810421L (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1244437A1 (en) * | 1999-12-06 | 2002-10-02 | Euro-Celtique, S.A. | Tertiary amino compounds having opioid receptor affinity |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0017376A1 (en) * | 1979-03-30 | 1980-10-15 | Kissei Pharmaceutical Co. Ltd | Phenylacetamide compounds and an analgesic composition containing them |
JPH01265080A (en) * | 1988-04-15 | 1989-10-23 | Nippon Chemiphar Co Ltd | Novel alkylenediamine derivative and glutamic acid blocker |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1101711A (en) * | 1964-01-23 | 1968-01-31 | Bellon Labor Sa Roger | New amides |
-
1977
- 1977-10-05 JP JP11978077A patent/JPS5455544A/en active Granted
-
1978
- 1978-10-02 GB GB7838905A patent/GB2006196A/en not_active Withdrawn
- 1978-10-03 BE BE78190893A patent/BE870992A/en unknown
- 1978-10-04 FR FR7828383A patent/FR2405240A1/en not_active Withdrawn
- 1978-10-04 IT IT51365/78A patent/IT1106921B/en active
- 1978-10-04 SE SE7810421A patent/SE7810421L/en unknown
- 1978-10-04 DE DE19782843328 patent/DE2843328A1/en not_active Withdrawn
- 1978-10-05 NL NL7810053A patent/NL7810053A/en unknown
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1244437A1 (en) * | 1999-12-06 | 2002-10-02 | Euro-Celtique, S.A. | Tertiary amino compounds having opioid receptor affinity |
EP1244437A4 (en) * | 1999-12-06 | 2005-02-09 | Euro Celtique Sa | Tertiary amino compounds having opioid receptor affinity |
US6984664B2 (en) * | 1999-12-06 | 2006-01-10 | Euro-Celtique, S.A. | Tertiary amino compounds having opioid receptor affinity |
Also Published As
Publication number | Publication date |
---|---|
JPS5455544A (en) | 1979-05-02 |
SE7810421L (en) | 1979-04-06 |
DE2843328A1 (en) | 1979-04-19 |
NL7810053A (en) | 1979-04-09 |
IT1106921B (en) | 1985-11-18 |
BE870992A (en) | 1979-02-01 |
FR2405240A1 (en) | 1979-05-04 |
JPS575219B2 (en) | 1982-01-29 |
IT7851365A0 (en) | 1978-10-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
WAP | Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1) |