GB1527699A - Process for producing 17-acetals of 3-alkoxyestra-2,5(10)-dien-17-ones - Google Patents
Process for producing 17-acetals of 3-alkoxyestra-2,5(10)-dien-17-onesInfo
- Publication number
- GB1527699A GB1527699A GB1539677A GB1539677A GB1527699A GB 1527699 A GB1527699 A GB 1527699A GB 1539677 A GB1539677 A GB 1539677A GB 1539677 A GB1539677 A GB 1539677A GB 1527699 A GB1527699 A GB 1527699A
- Authority
- GB
- United Kingdom
- Prior art keywords
- liquid ammonia
- dien
- acetals
- ones
- april
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/008—Ketals at position 17
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Abstract
1527699 Production of 17-acetals of 3-alkoxyester - 2,5(10) - dien - 17 - ones MITSUBISHI CHEMICAL INDUSTRIES Ltd 13 April 1977 [19 April 1976 7 Dec 1976] 15396/77 Heading C2U Steroids of the formula (wherein R 1 and R 2 are each C 1-10 alkyl or R 1 and R 2 together are C 2-10 alkylene, and R 3 is C 1-10 alkyl) are prepared by reacting steroids of the formula with sodium or potassium, liquid ammonia and a tertiary alcohol in the presence of tetrahydrofuran, dioxan or tetrahydropyran as solvent, these materials being used in such proportions that the starting steroid is substantially dissolved in the reaction system and that 2 liquid phases are formed, the upper consisting mainly of Na or K and liquid ammonia and the lower consisting mainly of solvent, liquid ammonia and starting steroid and being coloured by the presence of alkali metal. The reaction is preferably effected in the presence of an aliphatic and/or alicyclic hydrocarbon, e.g. of 5 to 8 carbon atoms. Examples are given, and comparative examples, in which the specified conditions are not necessarily adhered to, are also provided.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4429576A JPS52128362A (en) | 1976-04-19 | 1976-04-19 | Preparation of 17-acetal of 3-alkoxyestra-2,5(10)-diene-17-one |
JP14683576A JPS5371053A (en) | 1976-12-07 | 1976-12-07 | Preparation of 17-acetal of 3-alkoxyestra-2,5(10)-diene-17-one |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1527699A true GB1527699A (en) | 1978-10-04 |
Family
ID=26384146
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1539677A Expired GB1527699A (en) | 1976-04-19 | 1977-04-13 | Process for producing 17-acetals of 3-alkoxyestra-2,5(10)-dien-17-ones |
Country Status (5)
Country | Link |
---|---|
DD (1) | DD132347A5 (en) |
DE (1) | DE2717310A1 (en) |
FR (1) | FR2348931A1 (en) |
GB (1) | GB1527699A (en) |
NL (1) | NL7704220A (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59141600A (en) * | 1983-02-02 | 1984-08-14 | Mitsubishi Chem Ind Ltd | Preparation of estrone |
-
1977
- 1977-04-13 GB GB1539677A patent/GB1527699A/en not_active Expired
- 1977-04-18 DD DD19844877A patent/DD132347A5/en unknown
- 1977-04-18 NL NL7704220A patent/NL7704220A/en not_active Application Discontinuation
- 1977-04-19 DE DE19772717310 patent/DE2717310A1/en not_active Withdrawn
- 1977-04-19 FR FR7711713A patent/FR2348931A1/en active Granted
Also Published As
Publication number | Publication date |
---|---|
DE2717310A1 (en) | 1977-11-03 |
FR2348931B1 (en) | 1980-06-06 |
NL7704220A (en) | 1977-10-21 |
DD132347A5 (en) | 1978-09-20 |
FR2348931A1 (en) | 1977-11-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB1535295A (en) | Process for producing hydrogen | |
GB1304667A (en) | ||
GB1527699A (en) | Process for producing 17-acetals of 3-alkoxyestra-2,5(10)-dien-17-ones | |
GB1081776A (en) | Process and apparatus for the continuous manufacture of peroxydicarbonates | |
GB1286703A (en) | Process for production of 4,4'-thiobis(2,6-d-t-butylphenol) | |
GB1453005A (en) | Sulphated polyoxyalkylated alcohols | |
GB933868A (en) | Process for fluorinating steroids | |
GB1347032A (en) | Process for producing silicic acid | |
GB1497233A (en) | Triethylenediamine recovery | |
AU544962B2 (en) | Synthesis of prostaglandin analogues | |
GB1500646A (en) | Process for producing oxygen-containing cyclic fluoro compounds | |
GB1455220A (en) | ||
GB1392337A (en) | Process for the production of hydroxylamino-and aminoanthra- quinones | |
GB1345625A (en) | Process for producing acetic esters of butenediol | |
ES8102578A1 (en) | Process for the preparation of 7-(D(-)-alpha-amino-p-hydroxyphenylacetamido)desacetoxycephalosporanic acid | |
US4274951A (en) | Ore dressing process | |
GB1038917A (en) | Novel steroid derivatives and a process for their production | |
GB1366663A (en) | Process for the preparation of cyclopenta /f/ /1/ benzopyrans and 1h-naphto/2 1-6/ pyrans | |
GB1535711A (en) | Continuous production of phosphine | |
GB1409209A (en) | Process for preparing mercaptocarboxylic acid esters | |
GB1449914A (en) | 2,2, 10beta, 17 alpha-tetramethyl steroids a process for their preparation and compositions containing them | |
GB1361332A (en) | Process for the production of 3-chloroo-1-propanol | |
GB1293035A (en) | Process for the production of primary alkenols | |
GB1324613A (en) | Epoxy estranes and process for their preparation | |
GB920638A (en) | New cyclopentanophenanthrene compounds and process for the transformation thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |