GB1526914A - System for rate immunonephelometric analysis - Google Patents

System for rate immunonephelometric analysis

Info

Publication number
GB1526914A
GB1526914A GB2238777A GB2238777A GB1526914A GB 1526914 A GB1526914 A GB 1526914A GB 2238777 A GB2238777 A GB 2238777A GB 2238777 A GB2238777 A GB 2238777A GB 1526914 A GB1526914 A GB 1526914A
Authority
GB
United Kingdom
Prior art keywords
antigen
antibody
rate
maximum rate
nephelometric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2238777A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Coulter Inc
Original Assignee
Beckman Instruments Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/796,621 external-priority patent/US4157871A/en
Application filed by Beckman Instruments Inc filed Critical Beckman Instruments Inc
Publication of GB1526914A publication Critical patent/GB1526914A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/272—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration for following a reaction, e.g. for determining photometrically a reaction rate (photometric cinetic analysis)

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Theoretical Computer Science (AREA)
  • Mathematical Physics (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Spectrometry And Color Measurement (AREA)

Abstract

In the processes for nephelometric analysis of a sample containing an antigen or an antibody to be assayed, by the antigen/antibody reaction, where the concentration of antigen or of antibody is determined from the maximum rate of variation of the nephelometric signal as a function of time, a source of error lies in the uncertainty of carrying out the measurement under conditions of excess antigen or antibody. This uncertainty is removed by using characteristics of the curve of the maximum rate of variation of the nephelometric signal as a function of the time required to achieve this maximum rate.
GB2238777A 1976-06-02 1977-05-27 System for rate immunonephelometric analysis Expired GB1526914A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69208976A 1976-06-02 1976-06-02
US05/796,621 US4157871A (en) 1976-06-02 1977-05-16 System for rate immunonephelometric analysis

Publications (1)

Publication Number Publication Date
GB1526914A true GB1526914A (en) 1978-10-04

Family

ID=27104904

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2238777A Expired GB1526914A (en) 1976-06-02 1977-05-27 System for rate immunonephelometric analysis

Country Status (7)

Country Link
JP (1) JPS5313492A (en)
CA (1) CA1081497A (en)
CH (1) CH621628A5 (en)
DE (1) DE2724722C2 (en)
FR (1) FR2353860A1 (en)
GB (1) GB1526914A (en)
SE (1) SE442148B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56155836A (en) * 1980-05-02 1981-12-02 Mitsubishi Chem Ind Ltd Optical measuring method for liquid sample
JPS56168148A (en) * 1980-05-29 1981-12-24 Joko:Kk Automatic starting method of immunity nephelometric device
JPS576361A (en) * 1980-06-12 1982-01-13 Joko:Kk Method for deciding peak in dynamic measurement of immune nephelometric device
JPS576344A (en) * 1980-06-13 1982-01-13 Joko:Kk Method for removing noise in immune nephelometric analyzing apparatus
JPS5861447A (en) * 1981-10-08 1983-04-12 Japan Spectroscopic Co Laser type quantitatively determining apparatus of reaction product of antigen and antibody
JPS58173465A (en) * 1982-04-05 1983-10-12 Wako Pure Chem Ind Ltd Optical measuring method of antigen and antibody reaction
JPH0617914B2 (en) * 1983-03-18 1994-03-09 三菱化成株式会社 Method for measuring antigen-antibody reaction
JPH0617915B2 (en) * 1983-10-07 1994-03-09 三菱化成株式会社 Method for measuring antigen-antibody reaction
JPS6179164A (en) * 1984-09-26 1986-04-22 Amano Pharmaceut Co Ltd Reducing method of antigen-antibody reaction time
JPH01502187A (en) * 1986-12-02 1989-08-03 サントル・ナシオナル・ド・ラ・ルシェルシュ・シアンティフィック・（セ・エヌ・エール・エス） α-oligonucleotide
US5019999A (en) * 1988-09-30 1991-05-28 Technicon Instruments Corporation Immunoanalysis method for discriminating between antigen excess and antibody excess conditions
DE4221807C2 (en) * 1992-07-03 1994-07-14 Boehringer Mannheim Gmbh Method for the analytical determination of the concentration of a component of a medical sample
US5460668A (en) * 1994-07-11 1995-10-24 Automotive Systems Laboratory, Inc. Nonazide gas generating compositions with reduced toxicity upon combustion
DE19640121B4 (en) * 1996-09-28 2007-04-26 Dade Behring Marburg Gmbh Method for determining a time-dependent variable to be measured
JP5662655B2 (en) * 2009-06-01 2015-02-04 勤 桂 nozzle

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3881992A (en) * 1973-07-02 1975-05-06 Wilson Ralston Optical rate measurement method
DE2409273A1 (en) * 1974-02-27 1975-09-04 Behringwerke Ag METHOD AND DEVICE FOR MEASURING ANTIGEN-ANTIBODY REACTIONS

Also Published As

Publication number Publication date
CA1081497A (en) 1980-07-15
FR2353860B1 (en) 1981-11-20
CH621628A5 (en) 1981-02-13
SE442148B (en) 1985-12-02
FR2353860A1 (en) 1977-12-30
JPS5313492A (en) 1978-02-07
DE2724722C2 (en) 1983-02-24
JPS6110775B2 (en) 1986-03-31
DE2724722A1 (en) 1977-12-08
SE7706338L (en) 1977-12-03

Similar Documents

Publication Publication Date Title
GB1526914A (en) System for rate immunonephelometric analysis
ES431413A1 (en) Method of detecting antigens or antibodies
JPS5324015A (en) Method and apparatus for detection of antigen-antibody reaction
ATE30780T1 (en) PROCEDURE FOR DETERMINING BIOACTIVE SUBSTANCES.
JPS51114985A (en) Mothod to analyse urine, etc.
JPS5530692A (en) Method of immunological measuring
ES433418A1 (en) Test system
SE8102558L (en) IMMUNOLOGICAL DETERMINATION METHOD
FI800140A (en) FOERFARANDE FOER DETEKTERING AV HEMOGLOBIN I AVFOERING
SG38686G (en) Process and diagnostic agents for detecting redox reactons
DK150805C (en) CHEMICAL ANALYSIS FOR CONCENTRATION DETERMINATION BY REACTION RATE MEASUREMENT
NO175657C (en) Method for performing an immunological determination of an antigen in a liquid sample as well as reagents for use therein.
ES8302313A1 (en) Method for assaying antigen-antibody reactions and reagent therefor.
ES475984A1 (en) Enzyme modifier immunoassay
NO161287C (en) HOMOGENIC IMMUNOLOGICAL METHOD OF ANALYSIS, REAGENTS AND TESTING DEVICES FOR USE BY IMMUNO ANALYSIS DETERMINATION.
JPS51118826A (en) A method for determining immunoprotein
MY103022A (en) Monoclonal antibodies recognizing l-thyroxine
JPS51126194A (en) Signal processing unit for analyzers
DE3172219D1 (en) Hemolytic method for the kinetic determination of antistreptolysin o antibodies in blood or serum samples, using oxidised so
ES488774A1 (en) Method and reagent for the determination of creatine kinase MB.
JPS5653465A (en) Improved method in measurement of enzyme immunity
JPS5436996A (en) Calcium analytical method
JPS5347517A (en) Immobilized antibody membrane for antigen protein determinationmethod and its apparatus
JPS53148495A (en) Method and apparatus of measuring water contents of polyhydric alcohol base solutions
JPS5262488A (en) Detector

Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19960527