GB1470276A - Semi-automatic chromatographic separation apparatus - Google Patents

Semi-automatic chromatographic separation apparatus

Info

Publication number
GB1470276A
GB1470276A GB1543475A GB1543475A GB1470276A GB 1470276 A GB1470276 A GB 1470276A GB 1543475 A GB1543475 A GB 1543475A GB 1543475 A GB1543475 A GB 1543475A GB 1470276 A GB1470276 A GB 1470276A
Authority
GB
United Kingdom
Prior art keywords
columns
vessels
collector
solutions
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1543475A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sartorius Membranfilter GmbH
Original Assignee
Sartorius Membranfilter GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sartorius Membranfilter GmbH filed Critical Sartorius Membranfilter GmbH
Publication of GB1470276A publication Critical patent/GB1470276A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/466—Flow patterns using more than one column with separation columns in parallel
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/24—Automatic injection systems

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

1470276 Multiple liquid chromatography SARTORIUS MEMBRANFILTER GmbH 15 April 1975 [17 April 1974] 15434/75 Heading B1H An apparatus for the semi-automatic separation by column chromatography of n sample solutions simultaneously, each of which is separated in chromatography columns into at least two fractions by means of washing and/or buffer solutions, comprises a proportioning pump provided with n-channels each of which is connected upstream to a suction needle and downstream to a column of a group of n chromatography columns, a fraction collector disposed under the group of columns and provided with n collector vessels for each fraction, a carrier arm carrying the n suction needles which is movable into predetermined positions, both in the direction of and at right angles to the longitudinal axis of the suction needles, relative to a supporting surface for receiving vessels for the solutions, a carrier plate on to which carrier racks for the collector vessels can be placed in predetermined positions and which is movable under the group of columns, at right angles to the longitudinal axis of the columns, into predetermined operating positions for the collector vessels, and a timer control device having adjustable timing elements for controlling in a co-ordinated manner, the movements of the carrier arm, the proportioning pump, and the carrier plate. Methods are described of ensuring that the relative movement between suction needles and samples and between columns and receiving vessels is correctly indexed. The preferred pump is a hose pump Reference is made to analysing medicinal solutions for thyroid hormone.
GB1543475A 1974-04-17 1975-04-15 Semi-automatic chromatographic separation apparatus Expired GB1470276A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2418509A DE2418509C3 (en) 1974-04-17 1974-04-17 Device for the semi-automatic simultaneous column chromatographic separation of a large number of sample solutions

Publications (1)

Publication Number Publication Date
GB1470276A true GB1470276A (en) 1977-04-14

Family

ID=5913131

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1543475A Expired GB1470276A (en) 1974-04-17 1975-04-15 Semi-automatic chromatographic separation apparatus

Country Status (6)

Country Link
US (1) US3925207A (en)
JP (1) JPS512489A (en)
CH (1) CH596868A5 (en)
DE (1) DE2418509C3 (en)
FR (1) FR2268267B3 (en)
GB (1) GB1470276A (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4228008A (en) * 1979-04-05 1980-10-14 Hoffmann-La Roche Inc. Chromatographic device for simultaneous collection and evaporation of sequential volatile non-aqueous eluates
US4422941A (en) * 1980-09-08 1983-12-27 University Of Pittsburgh Apparatus for liquid-solid column centrifugation chromatography and method
JPS62138753A (en) * 1985-12-12 1987-06-22 Hitachi Ltd Method and apparatus for fractionating and dispesing by liquid chromatography
FR2600166B1 (en) * 1986-06-17 1988-10-07 Rhone Poulenc Rech PROCESS AND DEVICE FOR AUTOMATICALLY SUPPORTING AND ANALYZING SAMPLES OF PRODUCTS RANDOMIZED
JPH0658400B2 (en) * 1987-03-04 1994-08-03 株式会社巴川製紙所 Radiation detecting composition and radiation dosimetry sheet
US5107908A (en) * 1989-05-03 1992-04-28 Analytical Bio-Chemistry Laboratories, Inc. Apparatus for supporting a container for fluid material
US5091092A (en) * 1989-05-03 1992-02-25 Analytical Bio-Chemistry Laboratories, Inc. Single-loop chromatography system and method
US5228988A (en) * 1989-10-27 1993-07-20 Helena Laboratories Corporation Column analyzer system and improved chromatograph column for use in the system
US5207918A (en) * 1989-10-27 1993-05-04 Helena Laboratories Corporation Column analyzer system
US5045208A (en) * 1989-10-27 1991-09-03 Helena Laboratories Corporation Column analyzer system
US5443734A (en) * 1990-03-05 1995-08-22 Applied Separations, Inc. Programmable solid phase extraction and elution device
US5395521A (en) * 1991-05-31 1995-03-07 Board Of Regents, The University Of Texas System Automated column equilibration, column loading, column washing and column elution
FR2705582B1 (en) * 1993-05-25 1995-06-30 Commissariat Energie Atomique Automatic column chromatography treatment device and liquid detector usable in such a device.
DE19704477A1 (en) * 1997-02-06 1998-08-13 Solvay Pharm Gmbh Device and method for parallel chromatography
EP1025434A4 (en) * 1997-10-24 2006-10-18 Univ Northeastern A multichannel microscale system for high throughput preparative separation with comprehensive collection and analysis
US6652746B2 (en) * 2002-03-26 2003-11-25 Biotage, Inc. Chromatography system for automatically separating different compounds in a sample
FR2867089B1 (en) * 2004-03-03 2006-06-09 Bionisis Sa COMPONENT SEPARATION INSTALLATION IN SEVERAL PARALLEL WAYS
JP5843516B2 (en) * 2010-08-25 2016-01-13 アークレイ株式会社 Analysis apparatus and analysis method

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3156548A (en) * 1960-03-21 1964-11-10 Sinclair Research Inc Gas chromatography apparatus
US3504799A (en) * 1968-04-02 1970-04-07 Beckman Instruments Inc Sample injector
US3649203A (en) * 1968-11-22 1972-03-14 Ralston Purina Co Automatic analyzer
US3701609A (en) * 1971-05-13 1972-10-31 David G Bailey Apparatus for automatically adding preselected patterns of eluent solutions to a chromatographic column and monitoring and collecting eluted fractions

Also Published As

Publication number Publication date
CH596868A5 (en) 1978-03-31
DE2418509B2 (en) 1977-08-25
US3925207A (en) 1975-12-09
DE2418509C3 (en) 1978-04-27
FR2268267A1 (en) 1975-11-14
FR2268267B3 (en) 1978-10-06
JPS512489A (en) 1976-01-10
DE2418509A1 (en) 1975-10-30

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee