GB1429519A - Carbostyril derivatives and process for preparation thereof - Google Patents

Carbostyril derivatives and process for preparation thereof

Info

Publication number
GB1429519A
GB1429519A GB5765273A GB5765273A GB1429519A GB 1429519 A GB1429519 A GB 1429519A GB 5765273 A GB5765273 A GB 5765273A GB 5765273 A GB5765273 A GB 5765273A GB 1429519 A GB1429519 A GB 1429519A
Authority
GB
United Kingdom
Prior art keywords
formula
preparation
derivatives
carbostyril
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5765273A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP47125858A external-priority patent/JPS5239036B2/ja
Priority claimed from JP47125857A external-priority patent/JPS5239035B2/ja
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Publication of GB1429519A publication Critical patent/GB1429519A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1429519 Carbostyril derivatives OTSUKA PHARMACEUTICAL CO Ltd 12 Dec 1973 [14 Dec 1972 (2)] 57652/73 Heading C2C The invention comprises (2-hydroxy-3-alkylamino)propoxycarbostyril derivatives of Formula (I): in which R is a C 1 -C 4 alkyl group and acid addition salts thereof. They may be produced by reacting a 5-, 6-, 7- or 8-substituted carbostyril of Formula (II): in which Y is a group or a -CHOH-CH 2 X group in which X is a halogen with a C 1 -C 4 alkylamine. The compounds of Formula I may be used in pharmaceutical compositions.
GB5765273A 1972-12-14 1973-12-12 Carbostyril derivatives and process for preparation thereof Expired GB1429519A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP47125858A JPS5239036B2 (en) 1972-04-13 1972-12-14
JP47125857A JPS5239035B2 (en) 1972-12-14 1972-12-14

Publications (1)

Publication Number Publication Date
GB1429519A true GB1429519A (en) 1976-03-24

Family

ID=26462163

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5765273A Expired GB1429519A (en) 1972-12-14 1973-12-12 Carbostyril derivatives and process for preparation thereof

Country Status (1)

Country Link
GB (1) GB1429519A (en)

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee