GB1291864A - Mono thiachromone-2-carboxylic acids - Google Patents

Mono thiachromone-2-carboxylic acids

Info

Publication number
GB1291864A
GB1291864A GB7467/69A GB746769A GB1291864A GB 1291864 A GB1291864 A GB 1291864A GB 7467/69 A GB7467/69 A GB 7467/69A GB 746769 A GB746769 A GB 746769A GB 1291864 A GB1291864 A GB 1291864A
Authority
GB
United Kingdom
Prior art keywords
alkyl
inhalation
feb
pharmaceutically acceptable
acceptable derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7467/69A
Inventor
Richard Hazard
John King
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fisons Pharmaceuticals Ltd
Original Assignee
Fisons Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fisons Pharmaceuticals Ltd filed Critical Fisons Pharmaceuticals Ltd
Priority to GB7467/69A priority Critical patent/GB1291864A/en
Priority to IL33846A priority patent/IL33846A/en
Priority to FR7004568A priority patent/FR2034538B1/fr
Priority to DE19702006196 priority patent/DE2006196A1/en
Priority to CH196970A priority patent/CH551437A/en
Priority to CH178672A priority patent/CH557346A/en
Priority to CH178372A priority patent/CH551438A/en
Priority to DK66870AA priority patent/DK128420B/en
Priority to SE01744/70A priority patent/SE367634B/xx
Priority to NL7001922A priority patent/NL7001922A/xx
Priority to CH178472A priority patent/CH557811A/en
Priority to CH178572A priority patent/CH560712A5/xx
Priority to CA116,120A priority patent/CA967580A/en
Priority to JP47084684A priority patent/JPS4835267B1/ja
Priority to JP47084683A priority patent/JPS4835266B1/ja
Publication of GB1291864A publication Critical patent/GB1291864A/en
Priority to US05/455,348 priority patent/US3952013A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1291864 Anti-asthmatic medicines FISONS PHARMACEUTICALS Ltd 2 Feb 1970 [12 Feb 1969] 7467/69 Heading ASB [Also in Division C2] Therapeutic compositions for the treatment 'extrinsic' and 'intrinsic' asthma, and other conditions, such as hay fever, urticaria and autoimmune diseases, in which antigen-antibody reactions are responsible for disease, by administration orally, parenterally or topically, or by inhalation, comprise compounds of formula: or their pharmaceutically acceptable derivatives (e.g. salts, esters or amides), wherein one of V and W is O, and the other is S; and P, Q, R, T are each H, halogen, C 1-10 alkyl, OH, alkoxy, hydroxyalkoxy, alkoxyalkoxy, AcO, CO 2 H, NH 2 , alkyl-NH, (alkyl) 2 N, alkenyl, aralkyl (up to C 10 ), Ph, NO 2 , carboxylic ester, alkenyloxy or acyl, or an adjacent pair of P, Q, R, T together with the adjacent carbon atoms in the benzene ring form a fused 5- or 6-membered carbocyclic or heterocyclic ring. For administration by inhalation, the compositions may include a bronchodilator such as isoprenaline, adrenaline, orciprenaline, isoetharine or their pharmaceutically acceptable derivatives.
GB7467/69A 1969-02-12 1969-02-12 Mono thiachromone-2-carboxylic acids Expired GB1291864A (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
GB7467/69A GB1291864A (en) 1969-02-12 1969-02-12 Mono thiachromone-2-carboxylic acids
IL33846A IL33846A (en) 1969-02-12 1970-02-05 Derivatives of 1-thiachromone and 4-thionchromone,their preparation and pharmaceutical compositions containing them
FR7004568A FR2034538B1 (en) 1969-02-12 1970-02-10
DK66870AA DK128420B (en) 1969-02-12 1970-02-11 Analogous process for the preparation of thiachromone-2-carboxylic acids or their salts with bases.
CH178472A CH557811A (en) 1969-02-12 1970-02-11 PROCESS FOR THE PREPARATION OF PHARMACEUTICALLY ACTIVE COMPOUNDS.
CH178672A CH557346A (en) 1969-02-12 1970-02-11 PROCESS FOR THE PREPARATION OF PHARMACEUTICALLY ACTIVE COMPOUNDS.
CH178372A CH551438A (en) 1969-02-12 1970-02-11 PROCESS FOR THE PREPARATION OF PHARMACEUTICALLY ACTIVE COMPOUNDS.
DE19702006196 DE2006196A1 (en) 1969-02-12 1970-02-11 Chromone and thiachromone compounds and processes for their preparation
SE01744/70A SE367634B (en) 1969-02-12 1970-02-11
NL7001922A NL7001922A (en) 1969-02-12 1970-02-11
CH196970A CH551437A (en) 1969-02-12 1970-02-11 PROCESS FOR THE PREPARATION OF CHROMONE-CARBOXYLIC ACIDS.
CH178572A CH560712A5 (en) 1969-02-12 1970-02-11
CA116,120A CA967580A (en) 1969-02-12 1971-06-21 Phenylthiofumaric acids
JP47084684A JPS4835267B1 (en) 1969-02-12 1972-08-25
JP47084683A JPS4835266B1 (en) 1969-02-12 1972-08-25
US05/455,348 US3952013A (en) 1969-02-12 1974-03-27 1-Thiachromone-2-carboxylic acids and derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7467/69A GB1291864A (en) 1969-02-12 1969-02-12 Mono thiachromone-2-carboxylic acids

Publications (1)

Publication Number Publication Date
GB1291864A true GB1291864A (en) 1972-10-04

Family

ID=9833661

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7467/69A Expired GB1291864A (en) 1969-02-12 1969-02-12 Mono thiachromone-2-carboxylic acids

Country Status (9)

Country Link
JP (2) JPS4835266B1 (en)
CH (5) CH560712A5 (en)
DE (1) DE2006196A1 (en)
DK (1) DK128420B (en)
FR (1) FR2034538B1 (en)
GB (1) GB1291864A (en)
IL (1) IL33846A (en)
NL (1) NL7001922A (en)
SE (1) SE367634B (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4159273A (en) * 1974-11-30 1979-06-26 Fisons Limited Tricyclic mono-chromone-2-carboxylic acids
US4238606A (en) * 1974-11-30 1980-12-09 Fisons Limited Tricyclic mono-chromone-2-carboxylic acids
US4565882A (en) * 1984-01-06 1986-01-21 G. D. Searle & Co. Substituted dihydrobenzopyran-2-carboxylates
US4644071A (en) * 1984-07-11 1987-02-17 G. D. Searle & Co. Aralkoxy and aryloxyalkoxy kojic acid derivatives
US4665203A (en) * 1983-08-08 1987-05-12 G. D. Searle & Co. Substituted dihydrobenzopyrans useful as leukotriene D4 inhibitors
US4778903A (en) * 1983-12-12 1988-10-18 G. D. Searle & Co. Substituted dihydrobenzopyrans
US4888356A (en) * 1983-08-08 1989-12-19 G. D. Searle And Company Use of substituted dihydrobenzopyrans for allergy and inflammation

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1362782A (en) * 1970-08-26 1974-08-07 Fisons Ltd Tetrazole derivatives
BE769146A (en) * 1970-07-01 1971-11-03 Takeda Chemical Industries Ltd CHROMON-CARBOXYLIC ACID DERIVATIVES
GB1391615A (en) * 1971-09-30 1975-04-23 Fisons Ltd 4-oxo-4h-1-benzopyran and 4-oxo-4h-1-thia benzopyran derivatives
JPS50112055U (en) * 1974-02-22 1975-09-12
EP0079637B1 (en) * 1981-11-12 1987-01-28 FISONS plc Anti-srs-a carboxylic acid derivatives, processes for their production, and pharmaceutical formulation containing them

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4159273A (en) * 1974-11-30 1979-06-26 Fisons Limited Tricyclic mono-chromone-2-carboxylic acids
US4238606A (en) * 1974-11-30 1980-12-09 Fisons Limited Tricyclic mono-chromone-2-carboxylic acids
US4665203A (en) * 1983-08-08 1987-05-12 G. D. Searle & Co. Substituted dihydrobenzopyrans useful as leukotriene D4 inhibitors
US4888356A (en) * 1983-08-08 1989-12-19 G. D. Searle And Company Use of substituted dihydrobenzopyrans for allergy and inflammation
US4778903A (en) * 1983-12-12 1988-10-18 G. D. Searle & Co. Substituted dihydrobenzopyrans
US4565882A (en) * 1984-01-06 1986-01-21 G. D. Searle & Co. Substituted dihydrobenzopyran-2-carboxylates
US4644071A (en) * 1984-07-11 1987-02-17 G. D. Searle & Co. Aralkoxy and aryloxyalkoxy kojic acid derivatives

Also Published As

Publication number Publication date
FR2034538A1 (en) 1970-12-11
JPS4835266B1 (en) 1973-10-26
DE2006196A1 (en) 1970-11-05
IL33846A0 (en) 1970-04-20
JPS4835267B1 (en) 1973-10-26
SE367634B (en) 1974-06-04
FR2034538B1 (en) 1974-08-30
CH551438A (en) 1974-07-15
NL7001922A (en) 1970-08-14
DK128420B (en) 1974-04-29
CH557346A (en) 1974-12-31
CH557811A (en) 1975-01-15
CH560712A5 (en) 1975-04-15
IL33846A (en) 1976-04-30
CH551437A (en) 1974-07-15

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees