GB1398687A - Substituted oxazolidinones and pharmaceutical uses thereof - Google Patents
Substituted oxazolidinones and pharmaceutical uses thereofInfo
- Publication number
- GB1398687A GB1398687A GB1798673A GB1798673A GB1398687A GB 1398687 A GB1398687 A GB 1398687A GB 1798673 A GB1798673 A GB 1798673A GB 1798673 A GB1798673 A GB 1798673A GB 1398687 A GB1398687 A GB 1398687A
- Authority
- GB
- United Kingdom
- Prior art keywords
- radical
- formula
- april
- straight
- branched chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
1398687 Substituted oxazolidinones and pharmaceutical uses thereof SYNTHELABO 13 April 1973 [13 April 1972] 17986/73 Heading C2C The invention comprises compounds of formula in which Ar-O-CH 2 represents a 1-dihydronaphthoxy-methyl radical, the double bond in the hydrogenated ring being in the 5,6-, 6,7- or 7,8-position; each of R 1 and R 2 which may be the same or different represents a straight or branched chain C 1-6 alkyl radical, or R 1 and R 2 together with the adjacent nitrogen atom form a heterocyclic radical, said radical optionally containing one or more further hetero atoms, and A represents a straight or branched chain C 2-6 alkylene radical, or a pharmaceutically acceptable inorganic or organic acid addition salt thereof. These compounds may be prepared by reacting a carbonic acid derivative of formula R 3 R 4 CO, in which each of R 3 and R 4 which may be identical or different, represents a halogen atom, e.g. Cl, or an alkoxy or aralkoxy radical, e.g. -OC 2 H 5 or -OC 6 H 5 or an amino radical with an amino alcohol of formula in which Ar-O-CH 2 , R 1 and R 2 and A are as defined above. The invention also comprises anxiety dispelling pharmaceutical compositions which comprise at least one compound according to the invention together with an inert carrier or diluent. The compositions are suitable for oral administration.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7212909A FR2179582B1 (en) | 1972-04-13 | 1972-04-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1398687A true GB1398687A (en) | 1975-06-25 |
Family
ID=9096785
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1798673A Expired GB1398687A (en) | 1972-04-13 | 1973-04-13 | Substituted oxazolidinones and pharmaceutical uses thereof |
Country Status (5)
Country | Link |
---|---|
JP (1) | JPS4913166A (en) |
BE (1) | BE797969A (en) |
DE (1) | DE2318575A1 (en) |
FR (1) | FR2179582B1 (en) |
GB (1) | GB1398687A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5399574A (en) * | 1990-06-07 | 1995-03-21 | Burroughs Wellcome Co. | Indolyl tetrahydropyridines for treating migraine |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS544738Y2 (en) * | 1974-12-02 | 1979-02-28 | ||
DE2538424C2 (en) * | 1975-08-29 | 1983-01-05 | Nordmark-Werke Gmbh, 2000 Hamburg | 4-substituted 5-phenyl-oxazolidone- (2) - compounds and a pharmaceutical preparation containing them |
JPS6183170A (en) * | 1984-09-28 | 1986-04-26 | Nippon Chemiphar Co Ltd | Novel 1,3-oxazolidin-2-one derivative and its preparation |
JPH0620695Y2 (en) * | 1987-06-04 | 1994-06-01 | 日産自動車株式会社 | Mounting structure for automobile molded ceiling |
-
1972
- 1972-04-13 FR FR7212909A patent/FR2179582B1/fr not_active Expired
-
1973
- 1973-04-09 BE BE129819A patent/BE797969A/en unknown
- 1973-04-12 DE DE19732318575 patent/DE2318575A1/en active Pending
- 1973-04-13 GB GB1798673A patent/GB1398687A/en not_active Expired
- 1973-04-13 JP JP4206273A patent/JPS4913166A/ja active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5399574A (en) * | 1990-06-07 | 1995-03-21 | Burroughs Wellcome Co. | Indolyl tetrahydropyridines for treating migraine |
US5466699A (en) * | 1990-06-07 | 1995-11-14 | Burroughs Wellcome Co. | Indolyl compounds for treating migraine |
US5863935A (en) * | 1990-06-07 | 1999-01-26 | Zeneca Limited | Therapeutic heterocyclic compounds |
Also Published As
Publication number | Publication date |
---|---|
FR2179582B1 (en) | 1975-10-10 |
BE797969A (en) | 1973-10-09 |
JPS4913166A (en) | 1974-02-05 |
DE2318575A1 (en) | 1973-10-25 |
FR2179582A1 (en) | 1973-11-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IE45256L (en) | Quinazolone derivatives | |
IE38886L (en) | Quinoline-3-carboxamidotetrazole derivatives | |
GB1409768A (en) | Hererocyclic derivatives of a guanidine | |
GB1398687A (en) | Substituted oxazolidinones and pharmaceutical uses thereof | |
GB1275181A (en) | Ester ofhydroxyethylpiperazinylpropylidenetrifuoro-methyl-thiaxanthene | |
GB1268587A (en) | Phloramine derivatives | |
ATE204278T1 (en) | SEROTONINERGIC ERGOLINE DERIVATIVES | |
IE42784L (en) | Histidine derivatives | |
GB1399261A (en) | 1,3-diamino 2-propanols and process for their preparation | |
GB1451902A (en) | Bromo dihydrolysergic acid | |
GB1296431A (en) | ||
RU95110868A (en) | New condensed thiazole derivatives, process for preparation thereof, and pharmaceutical composition thereof | |
DK378087D0 (en) | TETRACYCLIC INCIDENTAL DERIVATIVES | |
GB1243955A (en) | Novel n-substituted amines and their process of preparation | |
GB1434645A (en) | Tetrazole coumarin derivatives | |
ES428535A1 (en) | N-substituted cycloserine compounds, salts thereof, and processes for preparing them | |
IE33249L (en) | Indolines | |
GB1316689A (en) | Trifamycin derivatives | |
GB1385639A (en) | Basically substituted coumarin derivatives | |
GB1295240A (en) | ||
DE3772850D1 (en) | THIADIAZINONE DERIVATIVES. | |
GB1292745A (en) | 4-alkyl-diphenylmethoxy-alkylamines and acid addition salts and pharmaceutical compositions thereof | |
GB1355198A (en) | Derivative of quinoline | |
GB1422831A (en) | Acylaminobenzimidazole derivatives | |
GB963830A (en) | 2-aryl-4-thiazolidone derivatives and a process for the manufacture thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PLNP | Patent lapsed through nonpayment of renewal fees |