GB1394170A - Process for the preparation of alpha-aminoxy-carboxylic acids - Google Patents

Process for the preparation of alpha-aminoxy-carboxylic acids

Info

Publication number
GB1394170A
GB1394170A GB3706572A GB3706572A GB1394170A GB 1394170 A GB1394170 A GB 1394170A GB 3706572 A GB3706572 A GB 3706572A GB 3706572 A GB3706572 A GB 3706572A GB 1394170 A GB1394170 A GB 1394170A
Authority
GB
United Kingdom
Prior art keywords
cooh
phenyl
hydrogen
aminoxy
carboxylic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3706572A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of GB1394170A publication Critical patent/GB1394170A/en
Expired legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1394170 α - Aminoxy - carboxylic acids RIGHTER GEDEON VEGYESZETI GYAR RT 9 Aug 1972 [12 Aug 1971] 37065/72 Heading C2C Compounds NH 2 -O-CH(R)-COOH in which R is hydrogen, phenyl or a C 1-6 alkyl group optionally substituted by phenyl, alkylthio, benzylthio, hydroxy, benzyloxy, benzyoxyphenyl, benzyloxycarbonyl amino or benzyloxycarboxylamino and the salts thereof, are prepared by reacting an N-protected hydroxylamine derivative of formula in which X is benzyl, p-chlorobenzyl or t-butyl, with the optically active (where R is not hydrogen) or racemic form of Y-CH(R)-COOH, in an organic solvent or a mixture of an organic solvent and water and in the presence of a monovalent metal hydroxide and if desired resolving the obtained compound of formula X-O-CO-NH-O-CH(R)-COOH and subjecting this compound to acid treatment at approximately ambient temperature. Compounds prepared are those in which R is hydrogen, phenyl or C 1-6 alkyl optionally substituted by methylthio, benzylthio, hydroxy, benzyloxy, amino, p-benzyloxyphenyl and carbobenzyloxy.
GB3706572A 1971-08-12 1972-08-09 Process for the preparation of alpha-aminoxy-carboxylic acids Expired GB1394170A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HURI440A HU165117B (en) 1971-08-12 1971-08-12

Publications (1)

Publication Number Publication Date
GB1394170A true GB1394170A (en) 1975-05-14

Family

ID=11000871

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3706572A Expired GB1394170A (en) 1971-08-12 1972-08-09 Process for the preparation of alpha-aminoxy-carboxylic acids

Country Status (6)

Country Link
JP (1) JPS5318484B2 (en)
AT (1) AT317863B (en)
CH (1) CH574899A5 (en)
FR (1) FR2150778B1 (en)
GB (1) GB1394170A (en)
HU (1) HU165117B (en)

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0008494A1 (en) * 1978-08-03 1980-03-05 Imperial Chemical Industries Plc Method of improving or maintaining digestibility of fodder crops
FR2443452A1 (en) * 1978-12-08 1980-07-04 Roussel Uclaf NEW PROCESS FOR THE SPLITTING OF DL CIS ACID AND DL CHRYSANTHEMIC TRANS
US4956474A (en) * 1985-04-01 1990-09-11 Mochida Pharmaceutical Co., Ltd. Intermediates of cephalosporin compounds
US5064953A (en) * 1983-12-29 1991-11-12 Mochida Pharmaceutical Co., Ltd. Intermediates cephalosporin derivatives
US20110313045A1 (en) * 1996-03-26 2011-12-22 President And Fellows Of Harvard College Histone deacetylases, and uses related thereto
CN102911085A (en) * 2012-10-24 2013-02-06 甘肃省化工研究院 Synthesis process of compound D-2- aminoxy-3-methylbutyric acid
US8716344B2 (en) 2009-08-11 2014-05-06 President And Fellows Of Harvard College Class- and isoform-specific HDAC inhibitors and uses thereof
US8754237B2 (en) 2006-02-14 2014-06-17 President And Fellows Of Harvard College Bifunctional histone deacetylase inhibitors
US8895284B2 (en) 2000-03-03 2014-11-25 President And Fellows Of Harvard College Class II human histone deacetylases, and uses related thereto
US8999289B2 (en) 2005-03-22 2015-04-07 President And Fellows Of Harvard College Treatment of protein degradation disorders
EP2682383A4 (en) * 2011-02-28 2015-12-09 Riken Auxin biosynthesis inhibitor
US9434686B2 (en) 2008-07-23 2016-09-06 President And Fellows Of Harvard College Deacetylase inhibitors and uses thereof
CN109942454A (en) * 2019-03-25 2019-06-28 西安集佰侬生物科技有限公司 A kind of ethylene antagonist and preparation method thereof

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4074057A (en) * 1973-12-12 1978-02-14 Takeda Chemical Co., Ltd. 2-Halopropionic acid and its derivatives
AU586229B2 (en) * 1985-04-01 1989-07-06 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
JPS6466147A (en) * 1987-09-08 1989-03-13 Dainippon Ink & Chemicals Production of aminooxyacetic acid salt
DE10357301A1 (en) * 2003-12-05 2005-07-07 Schebo Biotech Ag Compounds for the modulation of the glycolysis enzyme and / or transaminase complex

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0008494A1 (en) * 1978-08-03 1980-03-05 Imperial Chemical Industries Plc Method of improving or maintaining digestibility of fodder crops
FR2443452A1 (en) * 1978-12-08 1980-07-04 Roussel Uclaf NEW PROCESS FOR THE SPLITTING OF DL CIS ACID AND DL CHRYSANTHEMIC TRANS
US5064953A (en) * 1983-12-29 1991-11-12 Mochida Pharmaceutical Co., Ltd. Intermediates cephalosporin derivatives
US4956474A (en) * 1985-04-01 1990-09-11 Mochida Pharmaceutical Co., Ltd. Intermediates of cephalosporin compounds
US8426592B2 (en) * 1996-03-26 2013-04-23 President And Fellows Of Harvard College Histone deacetylases, and uses related thereto
US20110313045A1 (en) * 1996-03-26 2011-12-22 President And Fellows Of Harvard College Histone deacetylases, and uses related thereto
US8329945B2 (en) * 1996-03-26 2012-12-11 President And Fellows Of Harvard College Histone deacetylases, and uses related thereto
US8895284B2 (en) 2000-03-03 2014-11-25 President And Fellows Of Harvard College Class II human histone deacetylases, and uses related thereto
US8999289B2 (en) 2005-03-22 2015-04-07 President And Fellows Of Harvard College Treatment of protein degradation disorders
US9572854B2 (en) 2005-03-22 2017-02-21 President And Fellows Of Harvard College Treatment of protein degradation disorders
US10172905B1 (en) 2005-03-22 2019-01-08 President And Fellows Of Harvard College Treatment of protein degradation disorders
US8754237B2 (en) 2006-02-14 2014-06-17 President And Fellows Of Harvard College Bifunctional histone deacetylase inhibitors
US9434686B2 (en) 2008-07-23 2016-09-06 President And Fellows Of Harvard College Deacetylase inhibitors and uses thereof
US8716344B2 (en) 2009-08-11 2014-05-06 President And Fellows Of Harvard College Class- and isoform-specific HDAC inhibitors and uses thereof
US9540317B2 (en) 2009-08-11 2017-01-10 President And Fellows Of Harvard College Class- and isoform-specific HDAC inhibitors and uses thereof
US10059657B2 (en) 2009-08-11 2018-08-28 President And Fellows Of Harvard College Class-and isoform-specific HDAC inhibitors and uses thereof
EP2682383A4 (en) * 2011-02-28 2015-12-09 Riken Auxin biosynthesis inhibitor
US9259000B2 (en) 2011-02-28 2016-02-16 Riken Auxin biosynthesis inhibitor
CN102911085A (en) * 2012-10-24 2013-02-06 甘肃省化工研究院 Synthesis process of compound D-2- aminoxy-3-methylbutyric acid
CN109942454A (en) * 2019-03-25 2019-06-28 西安集佰侬生物科技有限公司 A kind of ethylene antagonist and preparation method thereof

Also Published As

Publication number Publication date
JPS4826728A (en) 1973-04-09
JPS5318484B2 (en) 1978-06-15
HU165117B (en) 1974-06-28
AT317863B (en) 1974-09-25
FR2150778B1 (en) 1976-04-16
CH574899A5 (en) 1976-04-30
FR2150778A1 (en) 1973-04-13

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee