GB1388001A - 2-pyridones and preparations comprising them - Google Patents
2-pyridones and preparations comprising themInfo
- Publication number
- GB1388001A GB1388001A GB3765072A GB3765072A GB1388001A GB 1388001 A GB1388001 A GB 1388001A GB 3765072 A GB3765072 A GB 3765072A GB 3765072 A GB3765072 A GB 3765072A GB 1388001 A GB1388001 A GB 1388001A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- unsubstituted
- substituted
- denotes
- radical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1388001 Pyridones CHEM PHARMAZ FABRIK DR HERMANN THIEMANN GmbH 11 Aug 1972 [13 Aug 1971] 37650/72 Heading C2C Novel compounds (I) (including salts thereof) wherein R<SP>1</SP> denotes a C 1 -C 6 -alkyl, a cycloalkyl or an unsubstituted or substituted aryl radical, R<SP>2</SP> denotes a C 1 -C 6 -alkyl, aralkyl or acyl radical, R<SP>3</SP> denotes a hydrogen atom or a free or esterified carboxyl radical, and R<SP>4</SP> denotes an alkyl, substituted or unsubstituted 2-arylethenyl, substituted or unsubstituted 2-arylethyl, substituted or unsubstituted 4-arylbutadienyl, substituted or unsubstituted 4-arylbutyl, 2- (C 1 -C 4 alkyl)-ethenyl, 2-(C 1 -C 4 -alkyl)-ethyl, 2 - (aryl - alkyl) - ethenyl or 2 - (aryl - alkyl)- ethyl radical, are made by standard methods. Pharmaceutical preparations having analgesic, antiphlogistic and muscle relaxing effect contain (I) as active ingredient. Administration may be orally, rectally and parenterally.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2140712A DE2140712A1 (en) | 1971-08-13 | 1971-08-13 | MEDICINAL PRODUCTS CONTAINING 2-PYRIDONES |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1388001A true GB1388001A (en) | 1975-03-19 |
Family
ID=5816721
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB3765072A Expired GB1388001A (en) | 1971-08-13 | 1972-08-11 | 2-pyridones and preparations comprising them |
Country Status (6)
Country | Link |
---|---|
BE (1) | BE787523A (en) |
DE (1) | DE2140712A1 (en) |
FR (1) | FR2150750B1 (en) |
GB (1) | GB1388001A (en) |
NL (1) | NL7210798A (en) |
ZA (1) | ZA725519B (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2591784A1 (en) * | 2005-05-10 | 2013-05-15 | Intermune, Inc. | Pyridine-2-one-derivatives as modulators of stress-activated protein kinase system |
US8969347B2 (en) | 2008-06-03 | 2015-03-03 | Intermune, Inc. | Compounds and methods for treating inflammatory and fibrotic disorders |
US9359379B2 (en) | 2012-10-02 | 2016-06-07 | Intermune, Inc. | Anti-fibrotic pyridinones |
US10233195B2 (en) | 2014-04-02 | 2019-03-19 | Intermune, Inc. | Anti-fibrotic pyridinones |
-
0
- BE BE787523D patent/BE787523A/en unknown
-
1971
- 1971-08-13 DE DE2140712A patent/DE2140712A1/en active Pending
-
1972
- 1972-08-07 NL NL7210798A patent/NL7210798A/xx not_active Application Discontinuation
- 1972-08-09 FR FR7228676A patent/FR2150750B1/fr not_active Expired
- 1972-08-11 ZA ZA725519A patent/ZA725519B/en unknown
- 1972-08-11 GB GB3765072A patent/GB1388001A/en not_active Expired
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2591784A1 (en) * | 2005-05-10 | 2013-05-15 | Intermune, Inc. | Pyridine-2-one-derivatives as modulators of stress-activated protein kinase system |
US9527816B2 (en) | 2005-05-10 | 2016-12-27 | Intermune, Inc. | Method of modulating stress-activated protein kinase system |
US10010536B2 (en) | 2005-05-10 | 2018-07-03 | Intermune, Inc. | Method of modulating stress-activated protein kinase system |
US8969347B2 (en) | 2008-06-03 | 2015-03-03 | Intermune, Inc. | Compounds and methods for treating inflammatory and fibrotic disorders |
US9290450B2 (en) | 2008-06-03 | 2016-03-22 | Intermune, Inc. | Compounds and methods for treating inflammatory and fibrotic disorders |
USRE47142E1 (en) | 2008-06-03 | 2018-11-27 | Intermune, Inc. | Compounds and methods for treating inflammatory and fibrotic disorders |
US9359379B2 (en) | 2012-10-02 | 2016-06-07 | Intermune, Inc. | Anti-fibrotic pyridinones |
US9675593B2 (en) | 2012-10-02 | 2017-06-13 | Intermune, Inc. | Anti-fibrotic pyridinones |
US10376497B2 (en) | 2012-10-02 | 2019-08-13 | Intermune, Inc. | Anti-fibrotic pyridinones |
US10898474B2 (en) | 2012-10-02 | 2021-01-26 | Intermune, Inc. | Anti-fibrotic pyridinones |
US10233195B2 (en) | 2014-04-02 | 2019-03-19 | Intermune, Inc. | Anti-fibrotic pyridinones |
US10544161B2 (en) | 2014-04-02 | 2020-01-28 | Intermune, Inc. | Anti-fibrotic pyridinones |
Also Published As
Publication number | Publication date |
---|---|
FR2150750B1 (en) | 1976-08-20 |
NL7210798A (en) | 1973-02-15 |
ZA725519B (en) | 1973-04-25 |
FR2150750A1 (en) | 1973-04-13 |
BE787523A (en) | 1973-02-12 |
DE2140712A1 (en) | 1973-02-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |