GB1388001A - 2-pyridones and preparations comprising them - Google Patents

2-pyridones and preparations comprising them

Info

Publication number
GB1388001A
GB1388001A GB3765072A GB3765072A GB1388001A GB 1388001 A GB1388001 A GB 1388001A GB 3765072 A GB3765072 A GB 3765072A GB 3765072 A GB3765072 A GB 3765072A GB 1388001 A GB1388001 A GB 1388001A
Authority
GB
United Kingdom
Prior art keywords
alkyl
unsubstituted
substituted
denotes
radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3765072A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
THIEMANN CHEM PHARM FAB
Original Assignee
THIEMANN CHEM PHARM FAB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by THIEMANN CHEM PHARM FAB filed Critical THIEMANN CHEM PHARM FAB
Publication of GB1388001A publication Critical patent/GB1388001A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/69—Two or more oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1388001 Pyridones CHEM PHARMAZ FABRIK DR HERMANN THIEMANN GmbH 11 Aug 1972 [13 Aug 1971] 37650/72 Heading C2C Novel compounds (I) (including salts thereof) wherein R<SP>1</SP> denotes a C 1 -C 6 -alkyl, a cycloalkyl or an unsubstituted or substituted aryl radical, R<SP>2</SP> denotes a C 1 -C 6 -alkyl, aralkyl or acyl radical, R<SP>3</SP> denotes a hydrogen atom or a free or esterified carboxyl radical, and R<SP>4</SP> denotes an alkyl, substituted or unsubstituted 2-arylethenyl, substituted or unsubstituted 2-arylethyl, substituted or unsubstituted 4-arylbutadienyl, substituted or unsubstituted 4-arylbutyl, 2- (C 1 -C 4 alkyl)-ethenyl, 2-(C 1 -C 4 -alkyl)-ethyl, 2 - (aryl - alkyl) - ethenyl or 2 - (aryl - alkyl)- ethyl radical, are made by standard methods. Pharmaceutical preparations having analgesic, antiphlogistic and muscle relaxing effect contain (I) as active ingredient. Administration may be orally, rectally and parenterally.
GB3765072A 1971-08-13 1972-08-11 2-pyridones and preparations comprising them Expired GB1388001A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2140712A DE2140712A1 (en) 1971-08-13 1971-08-13 MEDICINAL PRODUCTS CONTAINING 2-PYRIDONES

Publications (1)

Publication Number Publication Date
GB1388001A true GB1388001A (en) 1975-03-19

Family

ID=5816721

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3765072A Expired GB1388001A (en) 1971-08-13 1972-08-11 2-pyridones and preparations comprising them

Country Status (6)

Country Link
BE (1) BE787523A (en)
DE (1) DE2140712A1 (en)
FR (1) FR2150750B1 (en)
GB (1) GB1388001A (en)
NL (1) NL7210798A (en)
ZA (1) ZA725519B (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2591784A1 (en) * 2005-05-10 2013-05-15 Intermune, Inc. Pyridine-2-one-derivatives as modulators of stress-activated protein kinase system
US8969347B2 (en) 2008-06-03 2015-03-03 Intermune, Inc. Compounds and methods for treating inflammatory and fibrotic disorders
US9359379B2 (en) 2012-10-02 2016-06-07 Intermune, Inc. Anti-fibrotic pyridinones
US10233195B2 (en) 2014-04-02 2019-03-19 Intermune, Inc. Anti-fibrotic pyridinones

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2591784A1 (en) * 2005-05-10 2013-05-15 Intermune, Inc. Pyridine-2-one-derivatives as modulators of stress-activated protein kinase system
US9527816B2 (en) 2005-05-10 2016-12-27 Intermune, Inc. Method of modulating stress-activated protein kinase system
US10010536B2 (en) 2005-05-10 2018-07-03 Intermune, Inc. Method of modulating stress-activated protein kinase system
US8969347B2 (en) 2008-06-03 2015-03-03 Intermune, Inc. Compounds and methods for treating inflammatory and fibrotic disorders
US9290450B2 (en) 2008-06-03 2016-03-22 Intermune, Inc. Compounds and methods for treating inflammatory and fibrotic disorders
USRE47142E1 (en) 2008-06-03 2018-11-27 Intermune, Inc. Compounds and methods for treating inflammatory and fibrotic disorders
US9359379B2 (en) 2012-10-02 2016-06-07 Intermune, Inc. Anti-fibrotic pyridinones
US9675593B2 (en) 2012-10-02 2017-06-13 Intermune, Inc. Anti-fibrotic pyridinones
US10376497B2 (en) 2012-10-02 2019-08-13 Intermune, Inc. Anti-fibrotic pyridinones
US10898474B2 (en) 2012-10-02 2021-01-26 Intermune, Inc. Anti-fibrotic pyridinones
US10233195B2 (en) 2014-04-02 2019-03-19 Intermune, Inc. Anti-fibrotic pyridinones
US10544161B2 (en) 2014-04-02 2020-01-28 Intermune, Inc. Anti-fibrotic pyridinones

Also Published As

Publication number Publication date
FR2150750B1 (en) 1976-08-20
NL7210798A (en) 1973-02-15
ZA725519B (en) 1973-04-25
FR2150750A1 (en) 1973-04-13
BE787523A (en) 1973-02-12
DE2140712A1 (en) 1973-02-15

Similar Documents

Publication Publication Date Title
GB1384031A (en) N-substituted dihydropyridine compounds their production and their medicinal use
GB1380129A (en) Benzofuran derivatives and preparation thereof
GB1381184A (en) Sulphamides
GB1388001A (en) 2-pyridones and preparations comprising them
GB1171670A (en) Derivatives of 4-Aryl-3-Hydroxybutyric Acid
GB1091089A (en) Organic base salts of n-carbamyl-aspartic acids
IL34878A (en) Hydrochloride and hydrobromide acid addition salts of n-carboxy-arginine anhydride and n-carboxy histidine-anhydride,and their preparation
GB1262292A (en) Novel thiazoline derivatives, the preparation thereof and compositions containing the same
BE848918A (en) NEW DERIVATIVE OF PHENETHYLAMINE, ITS SALTS AND PHARMACEUTICAL COMPOSITIONS
GB1500300A (en) Pharmaceutical preparation for the treatment of circulatory disorders
CH550807A (en) DERIVATIVES OF 3,4-DIHYDRO-2,3- (LOWER ALKYL) -4OXO-1- (2H) QUINAZOLINECARBOXYLIC SUBSTITUTED IN 6 AND 7, USEFUL AS ANALGESIC AND TRANQUILIZING AGENTS.
IE35032B1 (en) Phenyl-azolyl-fatty acid derivatives,process for their production and their use as medicines
GB1297035A (en)
GB1260939A (en) beta-HYDRAZINO-ALKANOIC ACIDS AND PROCESSES FOR THEIR PREPARATION
GB1453490A (en) Herbicidal thioesters
GB1418288A (en) Anti-hypertensive compositions
GB1378964A (en) Pyridine derivatives
GB1468347A (en) Aminoindanes
GB1319197A (en) 3,4,5-trisubstituted benzoic acid derivatives and their uses
GB1330930A (en) Thiazole derivatives and a process for the manufacture thereof
SE409033B (en) PROCEDURE FOR THE PREPARATION OF 4-METHYL-2,3,4,5,6,7-HEXAHYDRO-1,6-NETANO-1H-4-BENZAZONE INTERVENTIONS AND PHARMACEUTICAL ACCEPTABLE SALTS THEREOF
GB1468079A (en) Ethanolamine derivatives
NZ182560A (en) Acid addition salts of n-(2-(3,4-methylene-dioxyphenyl)-ethyl)-i-(3-hydroxymethyl-4-hydroxyphenyl)-aminoethanol derivatives and pharmaceutical compositions
GB1166758A (en) Phenoxyacetic Acids
IE36780B1 (en) New pharmaceutical preparations

Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee