GB1384887A - Sustained release pharmaceutical tablet - Google Patents

Sustained release pharmaceutical tablet

Info

Publication number
GB1384887A
GB1384887A GB4133771A GB4133771A GB1384887A GB 1384887 A GB1384887 A GB 1384887A GB 4133771 A GB4133771 A GB 4133771A GB 4133771 A GB4133771 A GB 4133771A GB 1384887 A GB1384887 A GB 1384887A
Authority
GB
United Kingdom
Prior art keywords
sustained release
medicament
soluble
copolymers
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4133771A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to BE787973D priority Critical patent/BE787973A/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Priority to GB4133771A priority patent/GB1384887A/en
Priority to ZA725506A priority patent/ZA725506B/en
Priority to FR7230623A priority patent/FR2150931B1/fr
Priority to JP8828372A priority patent/JPS561288B2/ja
Publication of GB1384887A publication Critical patent/GB1384887A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Abstract

1384887 Sustained release medicament BEECHAM GROUP Ltd 8 Aug 1972 [4 Sept 1971] 41337/71 Heading A5B A pharmaceutical sustained release tablet comprises a mixture of 1-15% w/w medicament which is 1-25% w/w soluble in water and/or gastric juice at 37‹C, 1-15% w/w of a substantially insoluble resin and 50-98% of a slightly soluble, inert, inorganic filler which is 0-3% w/w soluble in water or gastric juice at 37‹C. Up to 3% w/w conventional tableting excipients may also be present. Suitable resins include methacrylate copolymers, cellulose esters (including celullose acetate phthalate), polyvinyl acetate and its copolymers, and styrene/maleic anhydride copolymers. Suitable inert, inorganic fillers are CaSO 4 . 2H 2 O, BaSO 4 , CaHPO 4 , magnesium pyrophosphate and tribasic magnesium phosphate. Medicaments mentioned include; metoclopramide, fenfluoramine, sodium phenobarbitone, ephedrine and prednisone. Manufacture may be by mixing a slurry of the medicament, filler, resin and optional ingredients, drying and grinding the mixture and compressing the powder into tablets.
GB4133771A 1971-09-04 1971-09-04 Sustained release pharmaceutical tablet Expired GB1384887A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
BE787973D BE787973A (en) 1971-09-04 DELAY-EFFECT PHARMACEUTICAL TABLETS
GB4133771A GB1384887A (en) 1971-09-04 1971-09-04 Sustained release pharmaceutical tablet
ZA725506A ZA725506B (en) 1971-09-04 1972-08-10 Sustained release pharmaceutical tablet
FR7230623A FR2150931B1 (en) 1971-09-04 1972-08-29
JP8828372A JPS561288B2 (en) 1971-09-04 1972-09-02

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4133771A GB1384887A (en) 1971-09-04 1971-09-04 Sustained release pharmaceutical tablet

Publications (1)

Publication Number Publication Date
GB1384887A true GB1384887A (en) 1975-02-26

Family

ID=10419222

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4133771A Expired GB1384887A (en) 1971-09-04 1971-09-04 Sustained release pharmaceutical tablet

Country Status (5)

Country Link
JP (1) JPS561288B2 (en)
BE (1) BE787973A (en)
FR (1) FR2150931B1 (en)
GB (1) GB1384887A (en)
ZA (1) ZA725506B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4917900A (en) * 1987-03-27 1990-04-17 Burroughs Wellcome Co. Controlled release formulations containing zidovudine
EP1207852A1 (en) * 1999-09-02 2002-05-29 Nostrum Pharmaceuticals, Inc. Controlled release oral dosage suitable for oral administration

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5541976A (en) * 1978-09-20 1980-03-25 Mazda Motor Corp Supply system for neutralizing agent at electrodeposition coating
JPS5597498A (en) * 1979-01-19 1980-07-24 Mazda Motor Corp Dipping and water washing system for electrodeposition coating
EP0022117A3 (en) * 1979-06-08 1981-11-11 Ady Trenker Metoclopramid resinate and medicament containing it
FR2492661A1 (en) * 1980-10-28 1982-04-30 Laruelle Claude NOVEL GALENIC FORM OF ADMINISTRATION OF METOCLOPRAMIDE, ITS PREPARATION METHOD AND MEDICINAL PRODUCT COMPRISING THIS NOVEL FORM
JPH0776172B2 (en) * 1986-04-16 1995-08-16 藤沢薬品工業株式会社 Matrice locks

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4917900A (en) * 1987-03-27 1990-04-17 Burroughs Wellcome Co. Controlled release formulations containing zidovudine
EP1207852A1 (en) * 1999-09-02 2002-05-29 Nostrum Pharmaceuticals, Inc. Controlled release oral dosage suitable for oral administration
EP1207852A4 (en) * 1999-09-02 2009-11-11 Nostrum Pharmaceuticals Inc Controlled release oral dosage suitable for oral administration

Also Published As

Publication number Publication date
FR2150931B1 (en) 1975-11-28
ZA725506B (en) 1973-04-25
BE787973A (en) 1973-02-26
JPS561288B2 (en) 1981-01-13
FR2150931A1 (en) 1973-04-13
JPS4833017A (en) 1973-05-07

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee