GB1343728A - Mechanism for control of pulsatile fluid flow especially for preserving animal organs - Google Patents

Mechanism for control of pulsatile fluid flow especially for preserving animal organs

Info

Publication number
GB1343728A
GB1343728A GB2644171*A GB2644171A GB1343728A GB 1343728 A GB1343728 A GB 1343728A GB 2644171 A GB2644171 A GB 2644171A GB 1343728 A GB1343728 A GB 1343728A
Authority
GB
United Kingdom
Prior art keywords
line
sleeve
pulsatile
modulator
flexible sleeve
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2644171*A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter International Inc
Original Assignee
Baxter Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Laboratories Inc filed Critical Baxter Laboratories Inc
Publication of GB1343728A publication Critical patent/GB1343728A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0236—Mechanical aspects
    • A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
    • A01N1/0247—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components for perfusion, i.e. for circulating fluid through organs, blood vessels or other living parts
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00—Surgery
    • Y10S128/03—Heart-lung

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

1343728 Fluid regulation BAXTER LABORATORIES Inc 19 April 1971 [6 April 1970] 26441/71 Heading G3H [ Also in Divisions A2 and F1] An apparatus for inparting a desired pulsatile characteristic to a fluid, comprises a pulsatile pump 12 having a flexible sleeve 44 which is contained within a tubular member 37 in a manner as to define an annular chamber 45, the chamber being in permanent communication with a reservoir 80. Oscillatory pressure applied to a line 78 of the reservoir 80 results in an alternate collapsing and expanding of the sleeve 44 and hence in a pulsatile outflow through the downstream one of two check valves 50 contained within the sleeve. Such flow then passes through a modulator in the form of a further flexible sleeve which is selectively subjectable to an oscillatory pressure applied to an annular space through a line 68. A further modulator is formed between the inlet line 34 and the upstream check valve 50, such further modulator having a flexible sleeve the inside of which communicates with inlet line 34 whilst the outside is subject to pressure pulses fed through line 76.
GB2644171*A 1970-04-06 1971-04-19 Mechanism for control of pulsatile fluid flow especially for preserving animal organs Expired GB1343728A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2578270A 1970-04-06 1970-04-06

Publications (1)

Publication Number Publication Date
GB1343728A true GB1343728A (en) 1974-01-16

Family

ID=21828030

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2644171*A Expired GB1343728A (en) 1970-04-06 1971-04-19 Mechanism for control of pulsatile fluid flow especially for preserving animal organs

Country Status (7)

Country Link
US (1) US3639084A (en)
AU (1) AU2618871A (en)
BE (1) BE764090A (en)
DE (1) DE2115333A1 (en)
FR (1) FR2092431A5 (en)
GB (1) GB1343728A (en)
ZA (1) ZA711359B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2327715B (en) * 1997-07-24 2001-11-21 Peter John Kimber Pumping of fluids

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3877843A (en) * 1973-05-21 1975-04-15 Baxter Laboratories Inc Pulsatile pumping system
US4080958A (en) * 1976-02-27 1978-03-28 Datascope Corporation Apparatus for aiding and improving the blood flow in patients
US4250872A (en) * 1978-05-25 1981-02-17 Yehuda Tamari Blood pulsating and/or pumping device
US4395492A (en) * 1981-06-03 1983-07-26 Res-Del Group Ltd. Perfusion chamber
US4417861A (en) * 1981-08-10 1983-11-29 Monsanto Company Cell culture pumping system
US4573883A (en) * 1985-03-01 1986-03-04 Baylor College Of Medicine Disposable blood pump
US4769241A (en) * 1986-09-23 1988-09-06 Alpha Therapeutic Corporation Apparatus and process for oxygenation of liquid state dissolved oxygen-carrying formulation
US4782817A (en) * 1987-05-29 1988-11-08 Abiomed Cardiovascular, Inc. Ventricular support system
JPH0653160B2 (en) * 1989-08-18 1994-07-20 呉羽化学工業株式会社 Beat generation method and device
US5217860A (en) * 1991-07-08 1993-06-08 The American National Red Cross Method for preserving organs for transplantation by vitrification
US5723282A (en) * 1991-07-08 1998-03-03 The American National Red Cross Method of preparing organs for vitrification
US5856081A (en) * 1991-07-08 1999-01-05 The American National Red Cross Computer controlled cryoprotectant perfusion apparatus
US5338662A (en) * 1992-09-21 1994-08-16 Bio-Preserve Medical Corporation Organ perfusion device
US5537335A (en) * 1993-11-01 1996-07-16 University Of Pittsburgh Of The Commonwealth System Of Higher Education Fluid delivery apparatus and associated method
US6638264B1 (en) 1995-05-16 2003-10-28 Biostratum Incorporation Perfusion apparatus and methods for pharmaceutical delivery
US6342214B1 (en) * 1995-05-16 2002-01-29 Karl Tryggvason Method for viral vector delivery
AU6265696A (en) * 1995-06-07 1996-12-30 St. Jude Medical Inc. Cardiovascular bioreactor apparatus and method
US5965433A (en) * 1996-05-29 1999-10-12 Trans D.A.T.A. Service, Inc. Portable perfusion/oxygenation module having mechanically linked dual pumps and mechanically actuated flow control for pulsatile cycling of oxygenated perfusate
US6642045B1 (en) * 1997-04-14 2003-11-04 Breonics, Inc. System for exsanguinous metabolic support of an organ or tissue
US8409846B2 (en) 1997-09-23 2013-04-02 The United States Of America As Represented By The Department Of Veteran Affairs Compositions, methods and devices for maintaining an organ
US6977140B1 (en) * 1998-09-29 2005-12-20 Organ Recovery Systems, Inc. Method for maintaining and/or restoring viability of organs
US6673594B1 (en) * 1998-09-29 2004-01-06 Organ Recovery Systems Apparatus and method for maintaining and/or restoring viability of organs
US7749693B2 (en) * 1998-09-29 2010-07-06 Lifeline Scientific, Inc. Method of determining that an organ is not suitable for transplantation and using it for testing substances
US20070166292A1 (en) * 1999-04-14 2007-07-19 Breonics, Inc. System for exsanguinous metabolic support of an organ or tissue
US6582953B2 (en) * 1999-04-14 2003-06-24 Breonics, Inc. Organ chamber for exsanguinous metabolic support system
US6345962B1 (en) * 2000-05-22 2002-02-12 Douglas E. Sutter Fluid operated pump
US7326564B2 (en) 2001-02-20 2008-02-05 St. Jude Medical, Inc. Flow system for medical device evaluation and production
JP2004529938A (en) * 2001-05-04 2004-09-30 ブレオニクス，インコーポレーティッド Organ chamber for blood-free metabolic support system
CA2521427C (en) * 2003-04-04 2012-11-20 Organ Recovery Systems, Inc. Device for separating gas from a liquid path
PL1613153T3 (en) * 2003-04-04 2021-11-29 Organ Recovery Systems, Inc. Methods and apparatus for perfusion, diagnosis, storage and/or transport of an organ or tissue
US7897327B2 (en) * 2003-06-02 2011-03-01 Organ Recovery Systems, Inc. Method and apparatus for pressure control for maintaining viability of organs
US7504201B2 (en) * 2004-04-05 2009-03-17 Organ Recovery Systems Method for perfusing an organ and for isolating cells from the organ
US8304181B2 (en) 2004-10-07 2012-11-06 Transmedics, Inc. Method for ex-vivo organ care and for using lactate as an indication of donor organ status
US9301519B2 (en) * 2004-10-07 2016-04-05 Transmedics, Inc. Systems and methods for ex-vivo organ care
CA2584066C (en) * 2004-10-07 2018-01-23 Transmedics, Inc. Systems and methods for ex-vivo organ care
EP1693025A1 (en) * 2005-02-17 2006-08-23 Universität Zürich Method of manufacturing a tissue-engineered prosthesis
US9078428B2 (en) 2005-06-28 2015-07-14 Transmedics, Inc. Systems, methods, compositions and solutions for perfusing an organ
US20100093066A1 (en) * 2005-08-26 2010-04-15 Regents Of The University Of Minnesota Decellularization and recellularization apparatuses and systems containing the same
ATE552007T1 (en) 2005-08-26 2012-04-15 Univ Minnesota DECELLULARIZATION AND RECELLULARIZATION OF ORGANS AND TISSUES
ES2625850T3 (en) * 2006-04-19 2017-07-20 Transmedics, Inc. Procedures for the care of ex vivo organs
US9457179B2 (en) * 2007-03-20 2016-10-04 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
SE531453C2 (en) * 2007-07-06 2009-04-07 Xenodevice Ab Organ evaluation and preservation system
US10750738B2 (en) * 2008-01-31 2020-08-25 Transmedics, Inc. Systems and methods for ex vivo lung care
US8329450B2 (en) 2008-08-01 2012-12-11 Biomedinnovations, Llc Methods and apparatus for organ support
US9576504B2 (en) * 2009-11-04 2017-02-21 University Of Scranton Mechanical model of the cardiovascular system and method of demonstrating the physiology of the cardiovascular system
US9881523B2 (en) 2009-11-04 2018-01-30 University Of Scranton Mechanical model of the cardiovascular system and method of demonstrating the physiology of the cardiovascular system
DE102010004600A1 (en) 2010-01-13 2011-07-14 Marseille, Oliver, Dr.-Ing., 52066 Arrangement with a blood pump and a gas exchanger for extracorporeal membrane oxygenation
WO2012031162A1 (en) 2010-09-01 2012-03-08 Doris Taylor Methods of recellularizing a tissue or organ for improved transplantability
DK2704560T3 (en) 2011-04-14 2022-05-23 Transmedics Inc ORGAN TREATMENT SOLUTION FOR EX-VIVO MACHINE PERFUSION OF DONOR LUNGS
US20140135697A1 (en) * 2011-06-20 2014-05-15 Veinux Aps Disposable heat exchange cassette and an assembly for heating intravenous fluid
US9290738B2 (en) 2012-06-13 2016-03-22 Miromatrix Medical Inc. Methods of decellularizing bone
WO2014151739A1 (en) 2013-03-15 2014-09-25 Miromatrix Medical Inc. Use of perfusion decellularized liver for islet cell recellularization
EP3151663B1 (en) 2014-06-02 2020-09-23 Transmedics, Inc. Ex vivo organ care system
EP3229588A4 (en) 2014-12-12 2019-03-13 Freed, Darren Apparatus and method for organ perfusion
JP6934005B2 (en) 2015-09-09 2021-09-08 トランスメディクス，インコーポレイテッド Aortic Cannula for Exobibo Organ Management System
EP3509651B1 (en) 2016-09-06 2022-12-28 Miromatrix Medical Inc. Use of resected liver serum for whole liver engineering
US11998662B1 (en) 2021-06-09 2024-06-04 Reprise Biomedical, Inc. Biologic matrix for a wound site and related methods

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2405734A (en) * 1944-08-19 1946-08-13 Harrison S Coe Pumping apparatus
US3490438A (en) * 1967-06-08 1970-01-20 Atomic Energy Commission Perfusion chamber and cannulae therefor

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2327715B (en) * 1997-07-24 2001-11-21 Peter John Kimber Pumping of fluids

Also Published As

Publication number Publication date
DE2115333A1 (en) 1971-10-21
FR2092431A5 (en) 1972-01-21
ZA711359B (en) 1971-12-29
US3639084A (en) 1972-02-01
AU2618871A (en) 1972-09-07
BE764090A (en) 1971-08-02

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees