GB1331216A - Inhaling device for medicinal powder compositions provided in capsule form - Google Patents

Inhaling device for medicinal powder compositions provided in capsule form

Info

Publication number
GB1331216A
GB1331216A GB2489272A GB2489272A GB1331216A GB 1331216 A GB1331216 A GB 1331216A GB 2489272 A GB2489272 A GB 2489272A GB 2489272 A GB2489272 A GB 2489272A GB 1331216 A GB1331216 A GB 1331216A
Authority
GB
United Kingdom
Prior art keywords
capsule
upper member
piercing
mixing chamber
ducts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2489272A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ISF SpA
Original Assignee
ISF SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ISF SpA filed Critical ISF SpA
Publication of GB1331216A publication Critical patent/GB1331216A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

1331216 Pocket inhalers ISF SpA 26 May 1972 [17 July 1971] 24892/72 Heading A5T A device for inhaling medicinal powders provided in a capsule 45 comprises a lower member 31 having a platform containing a cavity 40 for the capsule and an upper member 1, 2 which forms with the lower member a mixing chamber having ducts tangential to the mixing chamber, which upper member operates a reciprocating piercing member 8 to puncture the capsule and is provided with a telescopically extendable mouthpiece 12, 13, 14. The upper member is formed from two components 1, 2 which are adhesively secured together. The upper of these components 1 has descending pins 3 which fit into the gaps between trapezoidally shaped ribs 4 on the component 2 to form the tangential ducts. The piercing member 8 is resiliently biassed away from the capsule by a spring 9 and is moved against that spring by cam surfaces on the inside of a skirt on the component 2 which surrounds the platform when the upper member is rotated relative to the lower member. The mouthpiece contains a filter 53 to trap the debris from the capsule. Two diametrically opposed piercing members may be provided.
GB2489272A 1971-07-17 1972-05-26 Inhaling device for medicinal powder compositions provided in capsule form Expired GB1331216A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT26971/71A IT941426B (en) 1971-07-17 1971-07-17 SWIRL-CHAMBER INHALER FOR POWDER-SHAPING MEDICINAL SUBSTANCES

Publications (1)

Publication Number Publication Date
GB1331216A true GB1331216A (en) 1973-09-26

Family

ID=11220655

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2489272A Expired GB1331216A (en) 1971-07-17 1972-05-26 Inhaling device for medicinal powder compositions provided in capsule form

Country Status (10)

Country Link
US (1) US3807400A (en)
AT (1) AT333415B (en)
BE (1) BE781102A (en)
CA (1) CA999202A (en)
CH (1) CH563167A5 (en)
ES (1) ES208808Y (en)
FR (1) FR2146202B1 (en)
GB (1) GB1331216A (en)
IT (1) IT941426B (en)
NL (1) NL7305363A (en)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3973566A (en) * 1975-01-13 1976-08-10 Syntex Puerto Rico Inc. Inhalation device
US3991761A (en) * 1974-03-18 1976-11-16 Salvatore Cocozza Inhaler for powdered medicaments
EP0041783A1 (en) * 1980-06-06 1981-12-16 FISONS plc Inhalation device for powdered medicaments
DE3050005A1 (en) * 1979-10-30 1982-03-18 Riker Laboratories Inc BREATH ACTUATED DEVICES FOR ADMINISTERING POWDERED MEDICAMENTS
DK154473B (en) * 1973-09-18 1988-11-21 Boehringer Sohn Ingelheim INHALATOR FOR POWDERED SUBSTANCE
US4860740A (en) * 1980-10-30 1989-08-29 Riker Laboratories, Inc. Powder inhalation device
GB2253200A (en) * 1991-02-01 1992-09-02 Harris Pharma Ltd Inhalation apparatus and fracturable capsule for use therewith
DE4239402A1 (en) * 1992-11-24 1994-05-26 Bayer Ag Multiple dosage powder inhaler - has acceleration channel and dwell chamber for uniformly high drug dispersion
US5476093A (en) * 1992-02-14 1995-12-19 Huhtamaki Oy Device for more effective pulverization of a powdered inhalation medicament
US6575160B1 (en) 1997-08-07 2003-06-10 Art Slutsky Inhalation device

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1404338A (en) * 1972-08-04 1975-08-28 Beecham Group Ltd Device for the inhalation of medicaments
GB1459426A (en) * 1973-02-26 1976-12-22 Allen & Hanburys Ltd Inhalation devices
US4069819A (en) * 1973-04-13 1978-01-24 Societa Farmaceutici S.P.A. Inhalation device
GB1387954A (en) * 1973-05-08 1975-03-19 Miles Lab Insufflator
US3938516A (en) * 1975-01-13 1976-02-17 Syntex Puerto Rico, Inc. Inhalation device
US3964483A (en) * 1975-01-13 1976-06-22 Syntex Puerto Rico, Inc. Inhalation device
US4014336A (en) * 1975-01-13 1977-03-29 Syntex Puerto Rico, Inc. Inhalation device
US3948264A (en) * 1975-05-21 1976-04-06 Mead Johnson & Company Inhalation device
GB1562732A (en) * 1976-02-10 1980-03-12 Allen & Hanburys Ltd Device for dispensing medicaments
US4095596A (en) * 1976-11-26 1978-06-20 Smithkline Corporation Nasal inhaler
US4155359A (en) * 1977-05-23 1979-05-22 Antoni Zagorski Air filtering mask
DE2960616D1 (en) * 1978-05-03 1981-11-12 Fisons Plc Inhalation device
IT1222509B (en) * 1987-08-17 1990-09-05 Miat Spa INSUFFLATOR FOR THE ADMINISTRATION OF DRUGS IN THE FORM OF PRE-DOSED POWDER IN OPERATIONS
SE466684B (en) * 1989-03-07 1992-03-23 Draco Ab DEVICE INHALATOR AND PROCEDURE TO REGISTER WITH THE DEVICE INHALATOR MEDICATION
US6048857A (en) * 1989-10-17 2000-04-11 Ellinwood, Jr.; Everett H. Dosing method of administering medicaments via inhalation administration
GB9004781D0 (en) * 1990-03-02 1990-04-25 Glaxo Group Ltd Device
TW197380B (en) * 1990-03-02 1993-01-01 Glaxo Group Ltd
US6536427B2 (en) 1990-03-02 2003-03-25 Glaxo Group Limited Inhalation device
SK280967B6 (en) * 1990-03-02 2000-10-09 Glaxo Group Limited Inhalation device
IL98441A (en) * 1990-06-14 1995-12-31 Rhone Poulenc Rorer Ltd Powder inhalers
IT1243344B (en) * 1990-07-16 1994-06-10 Promo Pack Sa MULTI-DOSE INHALER FOR POWDER MEDICATIONS
US5161524A (en) * 1991-08-02 1992-11-10 Glaxo Inc. Dosage inhalator with air flow velocity regulating means
DE4208880A1 (en) * 1992-03-19 1993-09-23 Boehringer Ingelheim Kg SEPARATOR FOR POWDER INHALATORS
KR960701672A (en) * 1993-03-03 1996-03-28 윌리엄 피. 알트만 DRY POWDER INHALATOR MEDICAMENT CARRIER
US5388572A (en) * 1993-10-26 1995-02-14 Tenax Corporation (A Connecticut Corp.) Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same
US5388573A (en) * 1993-12-02 1995-02-14 Tenax Corporation Dry powder inhalator medicament carrier
US20040237961A1 (en) * 1995-06-08 2004-12-02 Snow John Medlin Inhalation actuated device for use with metered dose inhalers (MDIs)
US6672304B1 (en) 1995-06-08 2004-01-06 Innovative Devices, Llc Inhalation actuated device for use with metered dose inhalers (MDIs)
US6209538B1 (en) 1995-08-02 2001-04-03 Robert A. Casper Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US5823183A (en) * 1995-08-02 1998-10-20 Innovative Devices Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US5692496A (en) * 1995-08-02 1997-12-02 Innovative Devices, Llc Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US5988163A (en) * 1995-08-02 1999-11-23 Innovative Devices Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of delivery of medicament
US5669378A (en) * 1995-12-21 1997-09-23 Pera; Ivo Inhaling device
US6237591B1 (en) 1998-11-02 2001-05-29 Dura Pharmaceuticals, Inc. Turbine dry powder inhaler
US6202643B1 (en) * 1998-02-23 2001-03-20 Thayer Medical Corporation Collapsible, disposable MDI spacer and method
US6152130A (en) * 1998-06-12 2000-11-28 Microdose Technologies, Inc. Inhalation device with acoustic control
JP2002524107A (en) 1998-06-12 2002-08-06 マイクロドース・テクノロジーズ・インコーポレーテッド Pharmaceutical and pharmaceutical weighing, packaging and transport
US6142146A (en) * 1998-06-12 2000-11-07 Microdose Technologies, Inc. Inhalation device
DE19835346A1 (en) * 1998-08-05 2000-02-10 Boehringer Ingelheim Pharma Two-part capsule for pharmaceutical preparations for powder inhalers
AUPQ582100A0 (en) * 2000-02-24 2000-03-16 Irm Technologies Pty Ltd Nasal filter and sampler
DE60133723T2 (en) 2000-02-28 2009-07-02 PharmaKodex Ltd., Chippenham ADMINISTRATION SYSTEMS FOR ORAL MEDICINAL PRODUCTS TO BE USED
US6948494B1 (en) 2000-05-10 2005-09-27 Innovative Devices, Llc. Medicament container with same side airflow inlet and outlet and method of use
US7080644B2 (en) * 2000-06-28 2006-07-25 Microdose Technologies, Inc. Packaging and delivery of pharmaceuticals and drugs
US6722364B2 (en) * 2001-01-12 2004-04-20 Becton, Dickinson And Company Medicament inhalation delivery devices and methods for using the same
US6443152B1 (en) * 2001-01-12 2002-09-03 Becton Dickinson And Company Medicament respiratory delivery device
US7284553B2 (en) 2002-12-12 2007-10-23 Boehringer Ingelheim Pharma Gmbh & Co. Kg Powder inhaler comprising a chamber for a capsule for taking up a non-returnable capsule being filled with an active ingredient
DE10258360A1 (en) 2002-12-12 2004-06-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Chamber for accommodation of disposable capsules for powder inhalers has an inner surface with protruding elements serving as distance pieces between the capsules
CA2554068A1 (en) * 2004-02-06 2005-08-25 Microdose Technologies, Inc. A blister pack for use with an inhalation device
JP2007523700A (en) 2004-02-24 2007-08-23 マイクロドース・テクノロジーズ・インコーポレーテッド Flow direction detection inhaler
PL1718353T3 (en) * 2004-02-24 2020-06-01 Microdose Therapeutx, Inc. Synthetic jet based medicament delivery apparatus
WO2006051300A1 (en) * 2004-11-10 2006-05-18 Cipla Limited Inhaler
DE102005001332A1 (en) * 2005-01-11 2006-07-20 Boehringer Ingelheim Pharma Gmbh & Co. Kg Two-piece capsule with pre-closure for holding pharmaceutical preparations for powder inhalers
CA2900093C (en) 2005-05-18 2018-11-13 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
DE102005022862A1 (en) * 2005-05-18 2006-12-14 Airsec S.A.S Capsules for inhalers
US8546423B2 (en) * 2005-05-18 2013-10-01 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
DE102006009637A1 (en) 2005-10-28 2007-05-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhaler with mouthpiece with microbiological protection
DE102005054383B4 (en) 2005-11-15 2013-10-31 Boehringer Ingelheim Pharma Gmbh & Co. Kg Needle for punching powder capsules for inhalation
AU2007224178B2 (en) * 2006-03-03 2013-03-07 Stc.Unm Dry powder inhaler with aeroelastic dispersion mechanism
JP2009529991A (en) 2006-03-21 2009-08-27 バング アンド オルフセン メディコム アクティーゼルスカブ Inhaler flow path
EP2357015A3 (en) 2006-04-05 2012-07-25 MicroDose Therapeutx, Inc. Variable dose inhalation device
MX2008012784A (en) * 2006-04-05 2008-12-09 Microdose Technologies Inc Variable dose inhalation device.
DE102006016901A1 (en) 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Mouthpiece for an inhaler
DE102006016903A1 (en) 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg inhaler
DE102006016904A1 (en) 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg inhaler
MX2008016153A (en) * 2006-06-16 2009-01-20 Cipla Ltd Improved dry powder inhaler.
US20080163610A1 (en) * 2007-01-05 2008-07-10 Matthew Thomas Baird Method and system for regenerating exhaust system filtering and catalyst components using variable high engine idle
PL2121204T3 (en) 2007-01-12 2016-04-29 Opex Corp Method and apparatus for sorting items
US8415390B2 (en) 2008-05-30 2013-04-09 Microdose Therapeutx, Inc. Methods and compositions for administration of oxybutynin
US9119777B2 (en) 2008-05-30 2015-09-01 Microdose Therapeutx, Inc. Methods and compositions for administration of oxybutynin
US11224704B2 (en) * 2007-07-06 2022-01-18 Manta Devices, Llc Dose delivery device for inhalation
DE102007033860A1 (en) 2007-07-20 2009-01-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Test arrangement for testing sealing between mouthpiece of inhaler and user's lips has channel for secondary air around user's lips with second flow measurement device
EP2020249A1 (en) * 2007-08-01 2009-02-04 Boehringer Ingelheim Pharma GmbH & Co. KG Inhalator
US8439033B2 (en) 2007-10-09 2013-05-14 Microdose Therapeutx, Inc. Inhalation device
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ES2546025T3 (en) * 2008-01-24 2015-09-17 Vectura Delivery Devices Limited Inhaler
US8371294B2 (en) * 2008-02-29 2013-02-12 Microdose Therapeutx, Inc. Method and apparatus for driving a transducer of an inhalation device
TR200803525A2 (en) * 2008-05-16 2009-12-21 Bi̇lgi̇ç Mahmut Powder inhaler.
NZ592717A (en) 2008-10-07 2013-03-28 Mpex Pharmaceuticals Inc Aerosol fluoroquinolone formulations for improved pharmacokinetics comprising levofloxacin or ofloxacin and a di- or trivalent cation
WO2010042549A1 (en) 2008-10-07 2010-04-15 Mpex Pharmaceuticals, Inc. Inhalation of levofloxacin for reducing lung inflammation
DE202008015493U1 (en) 2008-11-21 2009-02-12 Boehringer Ingelheim Pharma Gmbh & Co. Kg folding
US8985101B2 (en) 2009-05-21 2015-03-24 Microdose Therapeutx, Inc. Method and device for clamping a blister within a dry powder inhaler
ES2682996T3 (en) * 2009-05-21 2018-09-24 Microdose Therapeutx, Inc. Rotating cassette system for dry powder inhaler
US20110000481A1 (en) * 2009-07-01 2011-01-06 Anand Gumaste Nebulizer for infants and respiratory compromised patients
US9180263B2 (en) * 2009-07-01 2015-11-10 Microdose Therapeutx, Inc. Laboratory animal pulmonary dosing device
ES2739979T3 (en) 2009-09-04 2020-02-05 Horizon Orphan Llc Use of levofloxacin spray for the treatment of cystic fibrosis
AU2010319328A1 (en) 2009-11-12 2012-05-31 Stc.Unm Dry powder inhaler with flutter dispersion member
US8991390B2 (en) 2010-01-05 2015-03-31 Microdose Therapeutx, Inc. Inhalation device and method
US8561609B2 (en) 2010-12-07 2013-10-22 Respira Therapeutics, Inc. Dry powder inhaler
DK2670242T3 (en) 2011-01-31 2022-05-02 Avalyn Pharma Inc Aerosol pirfenidone and pyridone analog compounds and uses thereof
US10463815B2 (en) 2012-02-21 2019-11-05 Respira Therapeutics, Inc. Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents
EP3027026A4 (en) 2013-07-31 2017-05-03 Windward Pharma, Inc. Aerosol tyrosine kinase inhibitor compounds and uses thereof
ZA201408393B (en) 2013-11-19 2015-11-25 Cipla Ltd Inhaler device
CA2936330C (en) 2014-01-10 2023-01-03 Genoa Pharmaceuticals Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
MX2016011003A (en) 2014-02-25 2016-11-30 Lupin Ltd Inhaler.
CA2943075C (en) 2014-03-19 2023-02-28 Infinity Pharmaceuticals, Inc. Heterocyclic compounds for use in the treatment of pi3k-gamma mediated disorders
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Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2573918A (en) * 1949-11-05 1951-11-06 Vick Chemical Company Device for dispensing medicaments
US3669113A (en) * 1966-03-07 1972-06-13 Fisons Ltd Inhalation device
US3507277A (en) * 1966-09-17 1970-04-21 Fisons Pharmaceuticals Ltd Inhalation device
GB1182779A (en) * 1966-09-17 1970-03-04 Fisons Pharmaceuticals Ltd Inhalation Device
GB1268051A (en) * 1968-06-07 1972-03-22 Fisons Pharmaceuticals Ltd Inhalation device

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK154473B (en) * 1973-09-18 1988-11-21 Boehringer Sohn Ingelheim INHALATOR FOR POWDERED SUBSTANCE
US3991761A (en) * 1974-03-18 1976-11-16 Salvatore Cocozza Inhaler for powdered medicaments
US3973566A (en) * 1975-01-13 1976-08-10 Syntex Puerto Rico Inc. Inhalation device
DE3050005A1 (en) * 1979-10-30 1982-03-18 Riker Laboratories Inc BREATH ACTUATED DEVICES FOR ADMINISTERING POWDERED MEDICAMENTS
EP0041783A1 (en) * 1980-06-06 1981-12-16 FISONS plc Inhalation device for powdered medicaments
US4860740A (en) * 1980-10-30 1989-08-29 Riker Laboratories, Inc. Powder inhalation device
GB2253200A (en) * 1991-02-01 1992-09-02 Harris Pharma Ltd Inhalation apparatus and fracturable capsule for use therewith
US5476093A (en) * 1992-02-14 1995-12-19 Huhtamaki Oy Device for more effective pulverization of a powdered inhalation medicament
DE4239402A1 (en) * 1992-11-24 1994-05-26 Bayer Ag Multiple dosage powder inhaler - has acceleration channel and dwell chamber for uniformly high drug dispersion
US5435301A (en) * 1992-11-24 1995-07-25 Bayer Aktiengesellschaft Powder inhaler having dispersing, discharge, and dwell-time chambers, along with an acceleration channel
US6575160B1 (en) 1997-08-07 2003-06-10 Art Slutsky Inhalation device

Also Published As

Publication number Publication date
CH563167A5 (en) 1975-06-30
FR2146202A1 (en) 1973-03-02
NL7305363A (en) 1974-05-07
IT941426B (en) 1973-03-01
BE781102A (en) 1972-07-17
US3807400A (en) 1974-04-30
FR2146202B1 (en) 1976-01-16
ATA346473A (en) 1976-03-15
CA999202A (en) 1976-11-02
AT333415B (en) 1976-11-25
ES208808U (en) 1976-04-01
ES208808Y (en) 1976-07-16

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
433D Application made for revocation (sect. 33/1949)
434A Offer to surrender (sect. 34/1949)
433 Proceeding terminated by voluntary surrender of the patent (sect. 33/1949)
434C Patent revoked (sect. 34/1949)