GB1404338A - Device for the inhalation of medicaments - Google Patents

Device for the inhalation of medicaments

Info

Publication number
GB1404338A
GB1404338A GB3642872A GB3642872A GB1404338A GB 1404338 A GB1404338 A GB 1404338A GB 3642872 A GB3642872 A GB 3642872A GB 3642872 A GB3642872 A GB 3642872A GB 1404338 A GB1404338 A GB 1404338A
Authority
GB
United Kingdom
Prior art keywords
housing
capsule
vent
vents
reed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3642872A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Priority to GB3642872A priority Critical patent/GB1404338A/en
Priority to IE1098/73A priority patent/IE38212B1/en
Priority to DE2335122A priority patent/DE2335122C3/en
Priority to IL42707A priority patent/IL42707A/en
Priority to AR249021A priority patent/AR196538A1/en
Priority to BE133791A priority patent/BE802702A/en
Priority to ZA735066A priority patent/ZA735066B/en
Priority to FR7327179A priority patent/FR2194454B1/fr
Priority to CA177,391A priority patent/CA1006060A/en
Priority to AT664073A priority patent/AT346466B/en
Priority to FI2429/73A priority patent/FI58076C/en
Priority to SE7310631A priority patent/SE392215B/en
Priority to IT51792/73A priority patent/IT990115B/en
Priority to LU68151A priority patent/LU68151A1/xx
Priority to CH1131773A priority patent/CH553579A/en
Priority to YU2113/73A priority patent/YU36613B/en
Priority to ES1973193872U priority patent/ES193872Y/en
Priority to NO3117/73A priority patent/NO133013C/no
Priority to NL7310742A priority patent/NL7310742A/xx
Priority to BR5927/73A priority patent/BR7305927D0/en
Priority to US477487A priority patent/US3888253A/en
Publication of GB1404338A publication Critical patent/GB1404338A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0031Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up by bursting or breaking the package, i.e. without cutting or piercing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • A61M15/0035Piercing means
    • A61M15/0036Piercing means hollow piercing means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • A61M15/0041Details of the piercing or cutting means with movable piercing or cutting means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder

Abstract

1404338 Administering medicines BEECHAM GROUP Ltd 2 Aug 1973 [4 Aug 1972] 36428/72 Heading A5T A device for the oral inhalation of finely divided solid medicaments comprises a hollow housing and a capsule holder fixed to an elongated vibratable member which is fixed at one end within the housing at a point remote from the capsule holder, the housing having inlet and outlet vents permitting air to flow through the housing, and means causing the member to vibrate, the outlet vents being adapted for application to or insertion into the mouth, and positioned such that the finely divided medicament is carried through the outlet vents at the intake of breath by the user of the device. As shown in Fig. 1, a hollow, generally cylindrical housing 1 has a flat reed 4 mounted on a projection 5 at the end of the housing. A capsule 3, containing finely divided medicament, is held in a holder 2 at the other end of reed 4. In use, the patient inhales at the outlet vents 7, so that air flows in through vents 6 to baffles 8 in the body and baffle 9 on reed 4. The baffles 8, 9 are arranged with a small gap between them, so that turbulence occurs in their vicinity. The reed is vibrated, and powder is shaken out of the capsule, which is pierced for the purpose, before loading or in situ. A constriction 10 is formed near the capsule to provide for low pressure to help disperse the powder. The housing 1 is made in two parts, with screw threads or a snap fastening at X, for placing the capsule in holder 2. Vents 6 may be omitted and air enters by a single vent or opposed vents in the side of the housing, co-operating with the reed or baffles mounted on opposite sides of the reed parallel to the housing walls. Vents 7 may be replaced by a plug drilled with a hole which has a cross-sectional area approximately equal to the area of the annular gap between a side vent and the reed at their greatest separation. In another embodiment, Fig. 6, air enters by tangential vents 406 (see also Fig. 7, not shown), and a vent 406a. A piercing member 421 slides coaxially in housing 401. As the patient inhales through the vent 407, a vortex is formed around holder 402, which rotates orbitally and strikes the inside of housing 401 successive light blows. Air is also drawn through vent 406a, passing partly through passage 417 and through capsule 403, adding to the turbulence. Consequently, powder issues from the capsule in a helical path. Lighter particles are inhaled through the vent 407; heavier particles whirl round in a trough 422 surrounding vent 407 until they are abraded to a size such that they also pass out through vent 407. The vibrating rod may be mounted on a spring-biassed pushbutton, and the capsule impaled on a hollow piercing member of the holder, so that it may be pushed on to a second piercing member by pressing the button. Where the patient is unable to suck sufficiently hard, his efforts may be supplemented by a rubber squeeze bulb.
GB3642872A 1972-08-04 1972-08-04 Device for the inhalation of medicaments Expired GB1404338A (en)

Priority Applications (21)

Application Number Priority Date Filing Date Title
GB3642872A GB1404338A (en) 1972-08-04 1972-08-04 Device for the inhalation of medicaments
IE1098/73A IE38212B1 (en) 1972-08-04 1973-07-02 Device for the inhalation of medicaments
DE2335122A DE2335122C3 (en) 1972-08-04 1973-07-10 Device for the oral inhalation of finely divided, solid medicaments
IL42707A IL42707A (en) 1972-08-04 1973-07-10 Device for the administration of medicaments by oral inhalation
AR249021A AR196538A1 (en) 1972-08-04 1973-07-11 A DEVICE FOR THE ORAL INHALATION OF SOLID MEDICINES, FINALLY DIVIDED
BE133791A BE802702A (en) 1972-08-04 1973-07-23 INHALER
ZA735066A ZA735066B (en) 1972-08-04 1973-07-25 Device for administration of medicines
FR7327179A FR2194454B1 (en) 1972-08-04 1973-07-25
CA177,391A CA1006060A (en) 1972-08-04 1973-07-26 Device for administration of medicines
AT664073A AT346466B (en) 1972-08-04 1973-07-27 DEVICE FOR ORAL INHALATION OF MEDICINES IN FINE DIVISIONAL FORM
FI2429/73A FI58076C (en) 1972-08-04 1973-08-01 ANORDNING FOER ORAL INHALATION AV FINFOERDELADE FASTA CEILINGS
SE7310631A SE392215B (en) 1972-08-04 1973-08-01 DEVICE FOR ORAL INHALATION OF FINE ADJUSTED, IN SOLID FORM AVAILABLE
IT51792/73A IT990115B (en) 1972-08-04 1973-08-02 DEVICE FOR ORAL INHALATION OF SOLID MEDICATIONS FINELY SOUR FACE
LU68151A LU68151A1 (en) 1972-08-04 1973-08-02
CH1131773A CH553579A (en) 1972-08-04 1973-08-03 DEVICE FOR ORAL INHALATION OF FINELY DISTRIBUTED SOLID DRUGS.
YU2113/73A YU36613B (en) 1972-08-04 1973-08-03 Device for applying medicments
ES1973193872U ES193872Y (en) 1972-08-04 1973-08-03 DEVICE FOR THE ORAL INHALATION OF SOLID FINALLY DIVIDED DRUGS.
NO3117/73A NO133013C (en) 1972-08-04 1973-08-03
NL7310742A NL7310742A (en) 1972-08-04 1973-08-03
BR5927/73A BR7305927D0 (en) 1972-08-04 1973-08-03 MEDICINE ADMINISTRATION APPLIANCE
US477487A US3888253A (en) 1972-08-04 1974-06-07 Device for administration of medicines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3642872A GB1404338A (en) 1972-08-04 1972-08-04 Device for the inhalation of medicaments

Publications (1)

Publication Number Publication Date
GB1404338A true GB1404338A (en) 1975-08-28

Family

ID=10388056

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3642872A Expired GB1404338A (en) 1972-08-04 1972-08-04 Device for the inhalation of medicaments

Country Status (20)

Country Link
AR (1) AR196538A1 (en)
AT (1) AT346466B (en)
BE (1) BE802702A (en)
BR (1) BR7305927D0 (en)
CA (1) CA1006060A (en)
CH (1) CH553579A (en)
DE (1) DE2335122C3 (en)
ES (1) ES193872Y (en)
FI (1) FI58076C (en)
FR (1) FR2194454B1 (en)
GB (1) GB1404338A (en)
IE (1) IE38212B1 (en)
IL (1) IL42707A (en)
IT (1) IT990115B (en)
LU (1) LU68151A1 (en)
NL (1) NL7310742A (en)
NO (1) NO133013C (en)
SE (1) SE392215B (en)
YU (1) YU36613B (en)
ZA (1) ZA735066B (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3050005A1 (en) * 1979-10-30 1982-03-18 Riker Laboratories Inc BREATH ACTUATED DEVICES FOR ADMINISTERING POWDERED MEDICAMENTS
US5724959A (en) * 1990-10-02 1998-03-10 Aea Technology Plc Powder inhaler with specific orifice and baffle arrangement
WO2006033585A1 (en) * 2004-09-23 2006-03-30 Glaxosmithkline Pharmaceuticals S.A. Powder inhaler, system for opening and emptying capsules
WO2011080761A1 (en) * 2009-12-30 2011-07-07 Thirumalai Anadampillai Aparna An improved dry powder inhaler
EP2362796A1 (en) * 2010-01-27 2011-09-07 Aespira Ltd. Dry powder inhaler
WO2013093469A3 (en) * 2011-12-20 2013-09-19 British American Tobacco (Investments) Limited Smoking articles, and other flow delivery articles
CN113490522A (en) * 2019-03-05 2021-10-08 菲利普莫里斯生产公司 Holder for an inhaler article

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE395611B (en) * 1975-12-12 1977-08-22 Draco Ab AEROSOL INHALATION DEVICE INTENDED FOR INHALATION THROUGH AN INHALATION MOUTH OF PHARMACOLOGICALLY ACTIVE SUBSTANCES
IT1116047B (en) * 1979-04-27 1986-02-10 Sigma Tau Ind Farmaceuti DEVICE FOR THE QUICK INHALATION OF POWDER DRUGS BY PERSONS SUFFERING FROM ASTHMA
BR8007911A (en) * 1979-12-06 1981-06-16 Glaxo Group Ltd PERFECTED INHALER

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2519555A (en) * 1945-08-31 1950-08-22 Abbott Lab Sterile medicament insufflator cartridge and insufflator
GB1301856A (en) * 1965-03-19 1973-01-04 Fisons Pharmaceuticals Ltd Dispensing device
US2946332A (en) * 1957-12-23 1960-07-26 Nysco Lab Inc Insufflator
GB1295081A (en) * 1969-01-08 1972-11-01 Fisons Pharmaceuticals Ltd A method and device for dispensing particulate medicament material from a container
GB1122284A (en) * 1965-03-19 1968-08-07 Fisons Pharmaceuticals Ltd Inhalation device
GB1118341A (en) * 1965-04-20 1968-07-03 Fisons Pharmaceuticals Ltd Inhalation device
DE1566604C3 (en) * 1966-09-17 1980-10-23 Fisons Pharmaceuticals Ltd., Loughborough, Leicestershire (Ver. Koenigreich) Device for the oral inhalation of medication in finely divided form
GB1182779A (en) * 1966-09-17 1970-03-04 Fisons Pharmaceuticals Ltd Inhalation Device
GB1268051A (en) * 1968-06-07 1972-03-22 Fisons Pharmaceuticals Ltd Inhalation device
GB1338254A (en) * 1970-03-25 1973-11-21 Fisons Ltd Powder blowing device
IT941426B (en) * 1971-07-17 1973-03-01 Isf Spa SWIRL-CHAMBER INHALER FOR POWDER-SHAPING MEDICINAL SUBSTANCES

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3050005A1 (en) * 1979-10-30 1982-03-18 Riker Laboratories Inc BREATH ACTUATED DEVICES FOR ADMINISTERING POWDERED MEDICAMENTS
US5724959A (en) * 1990-10-02 1998-03-10 Aea Technology Plc Powder inhaler with specific orifice and baffle arrangement
WO2006033585A1 (en) * 2004-09-23 2006-03-30 Glaxosmithkline Pharmaceuticals S.A. Powder inhaler, system for opening and emptying capsules
JP2008513178A (en) * 2004-09-23 2008-05-01 グラクソスミスクライン ファーマシューティカルズ エス.エー. Powder inhaler, system for opening capsule and taking out the contents
GB2489383A (en) * 2009-12-30 2012-09-26 Vijayan Thirumalai Anandampillai An improved dry powder inhaler
WO2011080761A1 (en) * 2009-12-30 2011-07-07 Thirumalai Anadampillai Aparna An improved dry powder inhaler
EP2362796A4 (en) * 2010-01-27 2014-10-08 Aespira Ltd Dry powder inhaler
EP2362796A1 (en) * 2010-01-27 2011-09-07 Aespira Ltd. Dry powder inhaler
WO2013093469A3 (en) * 2011-12-20 2013-09-19 British American Tobacco (Investments) Limited Smoking articles, and other flow delivery articles
CN104144619A (en) * 2011-12-20 2014-11-12 英美烟草(投资)有限公司 Smoking articles, and other flow delivery articles
AU2012356454B2 (en) * 2011-12-20 2015-07-16 British American Tobacco (Investments) Limited Smoking articles, and other flow delivery articles
RU2590990C2 (en) * 2011-12-20 2016-07-10 Бритиш Америкэн Тобэкко (Инвестментс) Лимитед Smoking products and other flow discharging articles
EP3272234A1 (en) * 2011-12-20 2018-01-24 British American Tobacco (Investments) Limited Smoking articles, and other flow delivery articles
RU2645647C1 (en) * 2011-12-20 2018-02-26 Бритиш Америкэн Тобэкко (Инвестментс) Лимитед Smoking products and other outstanding product flow
EP3295812A1 (en) * 2011-12-20 2018-03-21 British American Tobacco (Investments) Limited Smoking articles, and other flow delivery articles
CN113490522A (en) * 2019-03-05 2021-10-08 菲利普莫里斯生产公司 Holder for an inhaler article
CN113490522B (en) * 2019-03-05 2023-10-17 菲利普莫里斯生产公司 Holder for an inhaler product

Also Published As

Publication number Publication date
DE2335122B2 (en) 1980-10-23
NO133013B (en) 1975-11-17
AT346466B (en) 1978-11-10
BR7305927D0 (en) 1974-08-29
ES193872U (en) 1974-12-01
SE392215B (en) 1977-03-21
IT990115B (en) 1975-06-20
BE802702A (en) 1974-01-23
IE38212B1 (en) 1978-01-18
DE2335122A1 (en) 1974-02-14
FR2194454A1 (en) 1974-03-01
ATA664073A (en) 1978-03-15
IE38212L (en) 1974-02-04
YU36613B (en) 1984-08-31
ZA735066B (en) 1974-07-31
FI58076C (en) 1980-12-10
NL7310742A (en) 1974-02-06
LU68151A1 (en) 1973-10-15
FI58076B (en) 1980-08-29
CA1006060A (en) 1977-03-01
ES193872Y (en) 1975-03-16
FR2194454B1 (en) 1979-07-20
NO133013C (en) 1976-02-25
DE2335122C3 (en) 1981-08-06
IL42707A (en) 1976-06-30
YU211373A (en) 1982-06-18
CH553579A (en) 1974-09-13
AR196538A1 (en) 1974-02-06
IL42707A0 (en) 1973-10-25

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
429A Application made for amendment of specification (sect. 29/1949)
429H Application (made) for amendment of specification now open to opposition (sect. 29/1949)
429D Case decided by the comptroller ** specification amended (sect. 29/1949)
SPA Amended specification published
PCNP Patent ceased through non-payment of renewal fee