GB1293310A - Vaccine - Google Patents

Vaccine

Info

Publication number
GB1293310A
GB1293310A GB01385/71A GB1138571A GB1293310A GB 1293310 A GB1293310 A GB 1293310A GB 01385/71 A GB01385/71 A GB 01385/71A GB 1138571 A GB1138571 A GB 1138571A GB 1293310 A GB1293310 A GB 1293310A
Authority
GB
United Kingdom
Prior art keywords
virus
vaccine
varicella
tissue
april
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB01385/71A
Inventor
Maurice R Hilleman
Eugene B Buynak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB1293310A publication Critical patent/GB1293310A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A61K39/25—Varicella-zoster virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

1293310 Varicella vaccine MERCK & CO Inc 26 April 1971 [28 April 1970] 11385/71 Heading A5B A process for the preparation of a live varicella virus useful as an antigen in a vaccine that will evoke in man an antibody response against a virulent varicella virus without causing the severe clinical manifestations of the disease, comprises serially passaging the virulent virus at 30-34‹C in a tissue culture preparation comprising human diploid cell strains or primary cells of simian origin a sufficient number of times to attenuate the virus. The tissue culture preparation is suitably human foetal lung tissue or monkey testicular tissue.
GB01385/71A 1970-04-28 1971-04-26 Vaccine Expired GB1293310A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3276970A 1970-04-28 1970-04-28

Publications (1)

Publication Number Publication Date
GB1293310A true GB1293310A (en) 1972-10-18

Family

ID=21866708

Family Applications (1)

Application Number Title Priority Date Filing Date
GB01385/71A Expired GB1293310A (en) 1970-04-28 1971-04-26 Vaccine

Country Status (11)

Country Link
AT (1) AT303965B (en)
AU (1) AU2788871A (en)
BE (1) BE766333A (en)
DE (1) DE2120426A1 (en)
ES (1) ES390603A1 (en)
FR (1) FR2092100B1 (en)
GB (1) GB1293310A (en)
HU (1) HU163131B (en)
IL (1) IL36649A0 (en)
NL (1) NL7103524A (en)
ZA (1) ZA712711B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0043847A1 (en) * 1980-01-25 1982-01-20 The Wistar Institute Of Anatomy And Biology Highly attenuated varicella virus vaccine and production thereof

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2952825B1 (en) 2009-11-24 2012-05-25 Goaster Jacqueline Le USE OF A VZV / HSV3 VIRUS VACCINE FOR TREATING HERPETIC INFECTIONS WITH HSV1 VIRUS AND / OR HSV2 VIRUS

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0043847A1 (en) * 1980-01-25 1982-01-20 The Wistar Institute Of Anatomy And Biology Highly attenuated varicella virus vaccine and production thereof
EP0043847A4 (en) * 1980-01-25 1982-07-06 Wistar Inst Highly attenuated varicella virus vaccine and production thereof.

Also Published As

Publication number Publication date
HU163131B (en) 1973-06-28
AT303965B (en) 1972-12-27
BE766333A (en) 1971-10-27
IL36649A0 (en) 1971-06-23
FR2092100B1 (en) 1974-08-30
FR2092100A1 (en) 1972-01-21
ZA712711B (en) 1972-12-27
ES390603A1 (en) 1974-04-01
NL7103524A (en) 1971-11-01
AU2788871A (en) 1972-10-26
DE2120426A1 (en) 1971-11-11

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees