GB1286929A - Process for producing tetracycline by fermentation - Google Patents
Process for producing tetracycline by fermentationInfo
- Publication number
- GB1286929A GB1286929A GB30583/71A GB3058371A GB1286929A GB 1286929 A GB1286929 A GB 1286929A GB 30583/71 A GB30583/71 A GB 30583/71A GB 3058371 A GB3058371 A GB 3058371A GB 1286929 A GB1286929 A GB 1286929A
- Authority
- GB
- United Kingdom
- Prior art keywords
- tetracycline
- fermentation
- producing
- phenaethylicus
- loredana
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
- C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
1286929 Producing tetracycline ISTITUTO BIOCHIMICO ITALIANO DI LOREDANA LORENZINI SaS 30 June 1971 [17 April 1971] 30583/71 Heading C2A Tetracycline is produced by cultivating Strepto - myces phenaethylicus n. sp. (IMRU. 3948) under submerged aerobic conditions in an aqueous nutrient medium containing assimilable sources of carbon, nitrogen and inorganic salts. The micro-organism is a mutant of Streptomyces aureofaciens ATCC. 10762 obtained by treating the latter with phenethyl alcohol together with nitrosoguanidine, dimethyl sulphate or nitrosomethyl-urethane. The fermentation is preferably conducted at an initial pH of 5À8 to 6À7 and a temperature of 26 to 32 C. Tetracycline is recovered from the filtered broth as the free base or a salt thereof by conventional methods.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT23347/71A IT1047890B (en) | 1971-04-17 | 1971-04-17 | PROCESS FOR THE PRODUCTION OF TETRACYCLINE BY FERMENTATION |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1286929A true GB1286929A (en) | 1972-08-31 |
Family
ID=11206289
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB30583/71A Expired GB1286929A (en) | 1971-04-17 | 1971-06-30 | Process for producing tetracycline by fermentation |
Country Status (3)
Country | Link |
---|---|
CA (1) | CA989756A (en) |
GB (1) | GB1286929A (en) |
IT (1) | IT1047890B (en) |
-
1971
- 1971-04-17 IT IT23347/71A patent/IT1047890B/en active
- 1971-06-30 GB GB30583/71A patent/GB1286929A/en not_active Expired
- 1971-08-25 CA CA121,501A patent/CA989756A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
IT1047890B (en) | 1980-10-20 |
CA989756A (en) | 1976-05-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |