GB1263392A - Sustained release drug composition - Google Patents

Sustained release drug composition

Info

Publication number
GB1263392A
GB1263392A GB24256/69A GB2425669A GB1263392A GB 1263392 A GB1263392 A GB 1263392A GB 24256/69 A GB24256/69 A GB 24256/69A GB 2425669 A GB2425669 A GB 2425669A GB 1263392 A GB1263392 A GB 1263392A
Authority
GB
United Kingdom
Prior art keywords
sustained
sucrose
sustained release
drug composition
carboxy vinyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB24256/69A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corp filed Critical American Home Products Corp
Publication of GB1263392A publication Critical patent/GB1263392A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)

Abstract

1,263,392. Sustained-release medicaments. AMERICAN HOME PRODUCTS CORP. 13 May, 1969 [21 May, 1968; 13 Feb., 1969], No. 24256/69. Heading A5B. A delayed or sustained-release medicament is made by mixing together a drug a carboxy vinyl polymer and polyethylene glycol (P.E.G.) and tableting this mixture together with conventional tablet ingredients. Suitable carboxy vinyl polymers are acrylic acid polymers crosslinked with 0.75 to 2% of a polyallyl ether of sucrose having an average of about 5.8 allyl groups per molecule of sucrose. Suitable P.E.G.'s are those of molecular weight 1000 to 20,000 especially 4000 to 6000. Reference is made to compositions containing numerous known drugs.
GB24256/69A 1968-05-21 1969-05-13 Sustained release drug composition Expired GB1263392A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73074268A 1968-05-21 1968-05-21
US80082769A 1969-02-13 1969-02-13

Publications (1)

Publication Number Publication Date
GB1263392A true GB1263392A (en) 1972-02-09

Family

ID=27112101

Family Applications (1)

Application Number Title Priority Date Filing Date
GB24256/69A Expired GB1263392A (en) 1968-05-21 1969-05-13 Sustained release drug composition

Country Status (13)

Country Link
BE (1) BE733417A (en)
CA (1) CA955526A (en)
DE (1) DE1925919C3 (en)
DK (1) DK122708B (en)
ES (1) ES367431A1 (en)
FI (1) FI50833C (en)
FR (1) FR2035801B1 (en)
GB (1) GB1263392A (en)
IE (1) IE32806B1 (en)
IL (1) IL32200A (en)
NL (1) NL164200C (en)
PH (1) PH10312A (en)
SE (1) SE354184B (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2178658A (en) * 1985-07-26 1987-02-18 Vincent Processes Limited Sustained release tablets and a method of manufacture thereof
EP1247834A1 (en) * 1999-10-21 2002-10-09 Daiso Co., Ltd. Crosslinking agent based on polyallyl ether compound
EP1443901A2 (en) * 2001-11-13 2004-08-11 Yamanouchi Pharma Technologies, Inc. Soluble drug extended release system
WO2006119389A2 (en) * 2005-05-03 2006-11-09 Mutual Pharmaceutical Company, Inc. Quinine-containing controlled-release formulations

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8500724A (en) * 1985-03-13 1986-10-01 Univ Groningen DEVICES FOR REGULAR RELEASE OF ACTIVE SUBSTANCES AND METHOD OF MANUFACTURE THEREOF
US5603955A (en) * 1994-07-18 1997-02-18 University Of Cincinnati Enhanced loading of solutes into polymer gels

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3039933A (en) * 1957-10-07 1962-06-19 Premo Pharmaceutical Lab Inc Ethyl cellulose-polyethylene glycol tablet matrix
US3087860A (en) * 1958-12-19 1963-04-30 Abbott Lab Method of prolonging release of drug from a precompressed solid carrier
NL128902C (en) * 1960-06-06
US3158538A (en) * 1961-02-23 1964-11-24 White Lab Inc Antidiarrheal compositions and method of using
US3346449A (en) * 1963-09-27 1967-10-10 Hoffmann La Roche d-methorphan compositions and methods of making same
GB1043872A (en) * 1964-02-03 1966-09-28 Wiggins & Co Ltd Berry Improvements in and relating to electric heaters
NZ248552A (en) * 1993-08-31 1996-09-25 Ind Res Ltd Electroplating power supply: switchable bridge rectifier with output rectified

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2178658A (en) * 1985-07-26 1987-02-18 Vincent Processes Limited Sustained release tablets and a method of manufacture thereof
EP1247834A1 (en) * 1999-10-21 2002-10-09 Daiso Co., Ltd. Crosslinking agent based on polyallyl ether compound
EP1247834A4 (en) * 1999-10-21 2005-11-16 Daiso Co Ltd Crosslinking agent based on polyallyl ether compound
EP1443901A2 (en) * 2001-11-13 2004-08-11 Yamanouchi Pharma Technologies, Inc. Soluble drug extended release system
EP1443901A4 (en) * 2001-11-13 2010-06-16 Yamanouchi Pharma Tech Inc Soluble drug extended release system
WO2006119389A2 (en) * 2005-05-03 2006-11-09 Mutual Pharmaceutical Company, Inc. Quinine-containing controlled-release formulations
WO2006119389A3 (en) * 2005-05-03 2007-02-22 Mutual Pharmaceutical Co Quinine-containing controlled-release formulations

Also Published As

Publication number Publication date
CA955526A (en) 1974-10-01
IL32200A0 (en) 1969-07-30
IE32806B1 (en) 1973-12-12
IE32806L (en) 1969-11-21
FI50833B (en) 1976-04-30
IL32200A (en) 1973-10-25
ES367431A1 (en) 1971-05-01
DE1925919B2 (en) 1979-11-08
DK122708B (en) 1972-04-04
FR2035801B1 (en) 1974-08-30
PH10312A (en) 1976-11-25
NL164200C (en) 1980-12-15
DE1925919C3 (en) 1980-07-17
NL164200B (en) 1980-07-15
FR2035801A1 (en) 1970-12-24
BE733417A (en) 1969-11-21
NL6907794A (en) 1969-11-25
SE354184B (en) 1973-03-05
FI50833C (en) 1976-08-10
DE1925919A1 (en) 1969-11-27

Similar Documents

Publication Publication Date Title
GR3003420T3 (en) Buccal drug dosage form
JPS57120515A (en) Medicinal composition
IE40025B1 (en) Hexahydro-dibenzo (b,d) pyran-9-ones as psychotropic or sedative drugs
CA2009890A1 (en) Valproic acid
ES8402155A1 (en) Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
GB1263392A (en) Sustained release drug composition
GB1487334A (en) Pharmaceutical preparations comprising lisuride and/or physiologically tolerable salts thereof
IT7825994A0 (en) COATING COMPOSITION PROCEDURE FOR THE PREPARATION OF A LIQUID HAVING A HIGH CONTENT OF AN ACRYLATE COPOLYMER OF LOW IN SOLID PRODUCTS BASED ON THE MOLECULAR WEIGHT, AND OF AN ACRYLATE COPOLYMER SO OBTAINED.
GB1457546A (en) Pharmaceutical preparations comprising cephalosporin derivatives
BE792078A (en) NEW INDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICINAL PRODUCTS
GB1363047A (en) Pyrimidine derivative process for its preparation and its use as a medicament
BE787804A (en) NEW SPIRANNIC COMPOUNDS, THEIR PREPARATION AND THEIR APPLICATION AS MEDICINAL PRODUCTS
GB1446237A (en) Pharmaceutical preparations containing pyrazolones
AU476979B2 (en) 4'-alkoxyalkyleneoxy-5-benzylpyrimidines, their preparation and pharmaceutical compositions thereof
GB1440832A (en) Pharmaceutical preparation comprising antibiotics
GB1465771A (en) Pharmaceutical composition and use thereofd
GB1410909A (en) Pharmaceutical compositions
GB1328079A (en) Thiocyanatobenzothiazoles their preparation and compositions containing them
GB1279915A (en) 0-aryl-2,3,4,5-tetrahydro-1h-1,5-benzodiazepine-2-ones and a process for their preparation
IL45548A0 (en) 3,3'-methylene-bis-(4-hydroxy-5-azacoumarin),its preparation and pharmaceutical compositions containing it
IL43216A0 (en) Novel derivatives of desoxy-normorphine and norcodeine,their preparation and pharmaceutical compositions containing them
GB1294538A (en) Pharmaceutical compositions
RU96123569A (en) MEDICINAL PRODUCT
GB1333619A (en) Pharmaceutical compositions comprising 1-h or 2-h-indazolone-3 derivatives
BE801350A (en) NEW SPIRANNIC COMPOUNDS THEIR PREPARATION AND THEIR APPLICATION AS MEDICINAL PRODUCTS