GB1242812A - Amino-butryophenone derivatives and pharmaceutical compositions thereof - Google Patents

Amino-butryophenone derivatives and pharmaceutical compositions thereof

Info

Publication number
GB1242812A
GB1242812A GB913370A GB913370A GB1242812A GB 1242812 A GB1242812 A GB 1242812A GB 913370 A GB913370 A GB 913370A GB 913370 A GB913370 A GB 913370A GB 1242812 A GB1242812 A GB 1242812A
Authority
GB
United Kingdom
Prior art keywords
formula
derivatives
pharmaceutical compositions
compound
butryophenone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB913370A
Inventor
Masahiro Torigoe
Mitsuhiro Konishi
Tetsuo Yokobe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Welfide Corp
Original Assignee
Welfide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Welfide Corp filed Critical Welfide Corp
Priority to GB913370A priority Critical patent/GB1242812A/en
Publication of GB1242812A publication Critical patent/GB1242812A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28—Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1,242,812. Bis(chloroalkyl)aminobutyrophenone derivatives. YOSHITOMI PHARMACEUTICAL INDUSTRIES Ltd. 25 Feb., 1970, No. 9133/70. Heading C2C. Novel compounds of formula and salts thereof wherein R is H, CH 2 , CH 3 , Cl, Br or F and n is 2 or 3, are prepared by reaction of a compound of Formula II with a chlorinating agent. Intermediates of Formula II are prepared by reaction of a compound of formula or its ethylenedioxy ketal wherein Y is a reactive ester group, with an amine HN(C n H 2n OH) 2 followed if necessary by hydrolysis. Pharmaceutical compositions in conventional forms, preferably for parenteral administration, and having antineoplastic and analgesic activity comprise an above novel compound or salt and a carrier therefor.
GB913370A 1970-02-25 1970-02-25 Amino-butryophenone derivatives and pharmaceutical compositions thereof Expired GB1242812A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB913370A GB1242812A (en) 1970-02-25 1970-02-25 Amino-butryophenone derivatives and pharmaceutical compositions thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB913370A GB1242812A (en) 1970-02-25 1970-02-25 Amino-butryophenone derivatives and pharmaceutical compositions thereof

Publications (1)

Publication Number Publication Date
GB1242812A true GB1242812A (en) 1971-08-11

Family

ID=9866014

Family Applications (1)

Application Number Title Priority Date Filing Date
GB913370A Expired GB1242812A (en) 1970-02-25 1970-02-25 Amino-butryophenone derivatives and pharmaceutical compositions thereof

Country Status (1)

Country Link
GB (1) GB1242812A (en)

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