GB1175482A - Reduction of Corticosteroid Side Effects - Google Patents

Reduction of Corticosteroid Side Effects

Info

Publication number
GB1175482A
GB1175482A GB2078/68A GB207868A GB1175482A GB 1175482 A GB1175482 A GB 1175482A GB 2078/68 A GB2078/68 A GB 2078/68A GB 207868 A GB207868 A GB 207868A GB 1175482 A GB1175482 A GB 1175482A
Authority
GB
United Kingdom
Prior art keywords
corticosteroid
side effects
compositions
pyridyl
cortisone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2078/68A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Unimed Inc
Original Assignee
Unimed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unimed Inc filed Critical Unimed Inc
Publication of GB1175482A publication Critical patent/GB1175482A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

1,175,482. Corticosteroid compositions. UNIMED Inc. 15 Jan., 1968 [9 March, 1967], No. 2078/68. Heading A5B. Corticosteroid compositions with reduced corticosteroid side effects comprise a corticosteroid and at least one compound selected from beta-(2- or 4- pyridyl) alkyl alkylamines and dialkylamines; 1-(2<SP>1</SP>- or 41-pyridyl)-2, 3- cis- or trans-dicarboxylic acid cyclobutanes; alphapicolinic acid dialkylamides; and non- toxic acid addition salts thereof. Examples of anti-inflammatory corticosteroids include cortisone, cortisone phosphate, hydrocortisone and the acetate and 21-sodium succinate thereof, prednisone, dexamethasone and the sodium phosphate salt thereof, ACTH, corticosterone, 11-dehydrocorticosterone, 11-desoxycorticosterone and aldosterone. Suitable salts include the hydrochloride, sulphate, tartrate, fumarate and gluconate. The compositions may be administered orally, parenterally or topically in the form of tablets, ampoules, drops, suspensions or ointments. Corticosteroid side effects are reduced by administering to a non-human animal simultaneously with, before or after administration of the corticosteroid at least one of the above-mentioned compounds.
GB2078/68A 1967-03-09 1968-01-15 Reduction of Corticosteroid Side Effects Expired GB1175482A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62179167A 1967-03-09 1967-03-09

Publications (1)

Publication Number Publication Date
GB1175482A true GB1175482A (en) 1969-12-23

Family

ID=24491653

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2078/68A Expired GB1175482A (en) 1967-03-09 1968-01-15 Reduction of Corticosteroid Side Effects

Country Status (9)

Country Link
US (1) US3474168A (en)
BE (1) BE710504A (en)
DE (1) DE1667925A1 (en)
FR (1) FR7356M (en)
GB (1) GB1175482A (en)
IE (1) IE31885B1 (en)
IL (1) IL29319A (en)
NL (1) NL6801136A (en)
SE (1) SE347874B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4353896A (en) * 1981-06-08 1982-10-12 Levy Michael A Penetrating topical medicament
US5358943A (en) * 1987-12-29 1994-10-25 Clark Abbot F Use of tetrahydrocortisol to prevent elevations in intraocular pressure caused by corticosteroids
US4945089A (en) * 1987-12-29 1990-07-31 Alcon Laboratories, Inc. Use of tetrahydrocortexolone to prevent elevations in intraocular pressure caused by corticosteroids
US20060074063A1 (en) * 1995-12-29 2006-04-06 Fernandez-Pol Jose A Pharmacological agent and method of treatment

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2794763A (en) * 1955-01-27 1957-06-04 Pfizer & Co C Pressor amines
US3105010A (en) * 1959-06-19 1963-09-24 Schering Corp Steroid-amino acid compositions for preventing negative nitrogen balance
US3415833A (en) * 1964-04-16 1968-12-10 Unimed Inc Pyridyl-dicarboxylic acid cyclobutane derivatives
US3984304A (en) * 1974-11-11 1976-10-05 Ppg Industries, Inc. Electrode unit

Also Published As

Publication number Publication date
DE1667925A1 (en) 1971-07-22
IL29319A (en) 1971-11-29
US3474168A (en) 1969-10-21
FR7356M (en) 1969-10-20
IE31885B1 (en) 1973-02-07
SE347874B (en) 1972-08-21
NL6801136A (en) 1968-09-10
BE710504A (en) 1968-06-17
IE31885L (en) 1968-09-09

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees