GB1103177A - Process for the production of an isoxazole derivative - Google Patents

Process for the production of an isoxazole derivative

Info

Publication number
GB1103177A
GB1103177A GB2376566A GB2376566A GB1103177A GB 1103177 A GB1103177 A GB 1103177A GB 2376566 A GB2376566 A GB 2376566A GB 2376566 A GB2376566 A GB 2376566A GB 1103177 A GB1103177 A GB 1103177A
Authority
GB
United Kingdom
Prior art keywords
production
isoxazole derivative
hydroxy
isoxazole
aminomethylisoxazole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2376566A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
JR Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JR Geigy AG filed Critical JR Geigy AG
Publication of GB1103177A publication Critical patent/GB1103177A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/12—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

3 - Hydroxy - 5 - aminomethylisoxazole and its acid addition salts are prepared by reducing 3 - hydroxy - 5 - isoxazole carboxamide with diborane in an organic solvent, optionally followed by salt formation. Reference has been directed by the Comptroller to Specification 1,034,939.
GB2376566A 1965-05-31 1966-05-27 Process for the production of an isoxazole derivative Expired GB1103177A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH754265A CH449625A (en) 1965-05-31 1965-05-31 Process for the preparation of 3-hydroxy-5-aminomethyl-isoxazole (5-aminomethyl-3-isoxazolol)

Publications (1)

Publication Number Publication Date
GB1103177A true GB1103177A (en) 1968-02-14

Family

ID=4326769

Family Applications (2)

Application Number Title Priority Date Filing Date
GB1470767A Expired GB1103178A (en) 1965-05-31 1966-05-27 Process for the production of an isoxazole derivative
GB2376566A Expired GB1103177A (en) 1965-05-31 1966-05-27 Process for the production of an isoxazole derivative

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB1470767A Expired GB1103178A (en) 1965-05-31 1966-05-27 Process for the production of an isoxazole derivative

Country Status (6)

Country Link
AT (2) AT262281B (en)
BE (1) BE681719A (en)
CH (2) CH449627A (en)
ES (1) ES327331A1 (en)
GB (2) GB1103178A (en)
NL (1) NL6607413A (en)

Also Published As

Publication number Publication date
NL6607413A (en) 1966-12-01
AT262281B (en) 1968-06-10
CH449627A (en) 1968-01-15
AT258900B (en) 1967-12-11
CH449625A (en) 1968-01-15
GB1103178A (en) 1968-02-14
BE681719A (en) 1966-11-28
ES327331A1 (en) 1967-09-16

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