ES334816A1 - Process for the production of 6 -fluoro-16-methylene steroids - Google Patents

Process for the production of 6 -fluoro-16-methylene steroids

Info

Publication number
ES334816A1
ES334816A1 ES334816A ES334816A ES334816A1 ES 334816 A1 ES334816 A1 ES 334816A1 ES 334816 A ES334816 A ES 334816A ES 334816 A ES334816 A ES 334816A ES 334816 A1 ES334816 A1 ES 334816A1
Authority
ES
Spain
Prior art keywords
fluoro
production
steroids
methylene steroids
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES334816A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck KGaA
Original Assignee
E Merck AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by E Merck AG filed Critical E Merck AG
Publication of ES334816A1 publication Critical patent/ES334816A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Steroids of the formula (wherein R 1 is H, OH or Oacyl and R 2 is H or acyl) are prepared by dehydration and isomerization of the corresponding 5[alpha]-hydroxy- 6#-fluoro- -16 - methylene 17[alpha]-acyloxy -steroids. The products may be saponified to the 17[alpha]-ols.
ES334816A 1965-12-23 1966-12-22 Process for the production of 6 -fluoro-16-methylene steroids Expired ES334816A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEM0067768 1965-12-23

Publications (1)

Publication Number Publication Date
ES334816A1 true ES334816A1 (en) 1968-03-01

Family

ID=7312330

Family Applications (1)

Application Number Title Priority Date Filing Date
ES334816A Expired ES334816A1 (en) 1965-12-23 1966-12-22 Process for the production of 6 -fluoro-16-methylene steroids

Country Status (9)

Country Link
BE (1) BE691655A (en)
CH (1) CH476704A (en)
DE (1) DE1543256A1 (en)
ES (1) ES334816A1 (en)
FR (1) FR1505675A (en)
GB (1) GB1127167A (en)
IL (1) IL26917A (en)
NL (1) NL6615761A (en)
SE (1) SE304003B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4599463A (en) * 1984-12-24 1986-07-08 General Electric Company Process for the preparation of bisphenols

Also Published As

Publication number Publication date
FR1505675A (en) 1967-12-15
IL26917A (en) 1970-07-19
BE691655A (en) 1967-06-22
SE304003B (en) 1968-09-16
GB1127167A (en) 1968-09-11
CH476704A (en) 1969-08-15
NL6615761A (en) 1967-06-26
DE1543256A1 (en) 1969-09-11

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