GB1078054A - Novel steroid derivatives and a process for the preparation thereof - Google Patents
Novel steroid derivatives and a process for the preparation thereofInfo
- Publication number
- GB1078054A GB1078054A GB3697464A GB3697464A GB1078054A GB 1078054 A GB1078054 A GB 1078054A GB 3697464 A GB3697464 A GB 3697464A GB 3697464 A GB3697464 A GB 3697464A GB 1078054 A GB1078054 A GB 1078054A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- acyl group
- reducing
- steroid derivatives
- novel steroid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
Novel steroid derivatives having the formula <FORM:1078054/C2/1> wherein R and R1 are each hydrogen or an acyl group, said acyl group being a carboxylic acyl group having from 1-12 carbon atoms and a molecular weight less than about 200 are obtained by reducing a 3-thiocyanatosteroid represented by the formula <FORM:1078054/C2/2> wherein A is a carbonyl, b -hydroxymethylene, or b -acyloxymethylene group, with a reducing agent capable of reducing a thiocyanate group to a mercapto group, and a carbonyl group to an hydroxyl group, and if desired, to prepare derivatives wherein R is an acyl group, subsequently reacting the 3-mercapto group with an acylating agent. Pharmaceutical compositions containing the above compounds are useful as anti-progestational, anti-uterotropic and anti-deciduomatogenic agents.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB3697464A GB1078054A (en) | 1964-09-09 | 1964-09-09 | Novel steroid derivatives and a process for the preparation thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB3697464A GB1078054A (en) | 1964-09-09 | 1964-09-09 | Novel steroid derivatives and a process for the preparation thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1078054A true GB1078054A (en) | 1967-08-02 |
Family
ID=10392701
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB3697464A Expired GB1078054A (en) | 1964-09-09 | 1964-09-09 | Novel steroid derivatives and a process for the preparation thereof |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB1078054A (en) |
-
1964
- 1964-09-09 GB GB3697464A patent/GB1078054A/en not_active Expired
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