GB1055492A - Process for the production of corticoid-21-esters - Google Patents

Process for the production of corticoid-21-esters

Info

Publication number
GB1055492A
GB1055492A GB37764A GB37764A GB1055492A GB 1055492 A GB1055492 A GB 1055492A GB 37764 A GB37764 A GB 37764A GB 37764 A GB37764 A GB 37764A GB 1055492 A GB1055492 A GB 1055492A
Authority
GB
United Kingdom
Prior art keywords
group
corticoid
esters
hydrogen
combination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB37764A
Inventor
Joachim Heider
Dietrich Jerchel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Priority to GB37764A priority Critical patent/GB1055492A/en
Publication of GB1055492A publication Critical patent/GB1055492A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)

Abstract

The invention comprises a process for preparing corticoid esters of formula <FORM:1055492/C2/1> wherein R1 and R2 are hydrogen atoms or in combination a double bond, R3 is a b -hydroxy or keto group, X is a hydrogen or fluorine atom, Y is a hydrogen atom or a hydroxyl or methyl group or, in combination with the 17a -hydroxy group, a 16a ,17a -diol acetonide group, and Z is a direct link or a carbonyl or methylene group, by reaction of the esterifying acid first with N,N1-thionyl-di-imidazole and then with the steroid alcohol.
GB37764A 1964-01-03 1964-01-03 Process for the production of corticoid-21-esters Expired GB1055492A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB37764A GB1055492A (en) 1964-01-03 1964-01-03 Process for the production of corticoid-21-esters

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB37764A GB1055492A (en) 1964-01-03 1964-01-03 Process for the production of corticoid-21-esters

Publications (1)

Publication Number Publication Date
GB1055492A true GB1055492A (en) 1967-01-18

Family

ID=9703349

Family Applications (1)

Application Number Title Priority Date Filing Date
GB37764A Expired GB1055492A (en) 1964-01-03 1964-01-03 Process for the production of corticoid-21-esters

Country Status (1)

Country Link
GB (1) GB1055492A (en)

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