FR3054564B1 - Substrat specifique d'une isoenzyme de l'aldh - Google Patents

Substrat specifique d'une isoenzyme de l'aldh Download PDF

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Publication number
FR3054564B1
FR3054564B1 FR1657324A FR1657324A FR3054564B1 FR 3054564 B1 FR3054564 B1 FR 3054564B1 FR 1657324 A FR1657324 A FR 1657324A FR 1657324 A FR1657324 A FR 1657324A FR 3054564 B1 FR3054564 B1 FR 3054564B1
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FR
France
Prior art keywords
aldh
isoenzyme
substrate specific
substrate
specific
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1657324A
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English (en)
Other versions
FR3054564A1 (fr
Inventor
Ismail Ceylan
Guillaume Martin
Gerard Quash
Milleidys PEREZ-ALEA
Guy Fournet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADVANCED BIODESIGN, FR
Original Assignee
ADVANCED BIODESIGN
Centre National de la Recherche Scientifique CNRS
Universite Claude Bernard Lyon 1 UCBL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Priority to FR1657324A priority Critical patent/FR3054564B1/fr
Application filed by ADVANCED BIODESIGN, Centre National de la Recherche Scientifique CNRS, Universite Claude Bernard Lyon 1 UCBL filed Critical ADVANCED BIODESIGN
Priority to EP17749666.8A priority patent/EP3491143A1/fr
Priority to JP2019503937A priority patent/JP7050748B2/ja
Priority to CA3031587A priority patent/CA3031587A1/fr
Priority to PCT/EP2017/068985 priority patent/WO2018019927A1/fr
Priority to CN201780057477.5A priority patent/CN109715822A/zh
Priority to US16/320,071 priority patent/US11519014B2/en
Priority to IL264481A priority patent/IL264481B1/en
Publication of FR3054564A1 publication Critical patent/FR3054564A1/fr
Application granted granted Critical
Publication of FR3054564B1 publication Critical patent/FR3054564B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/007Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving isoenzyme profiles
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2334/00O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
    • C12Q2334/20Coumarin derivatives
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2334/00O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
    • C12Q2334/40Triphenylmethane dye chromogens, e.g. fluorescein derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FR1657324A 2016-07-28 2016-07-28 Substrat specifique d'une isoenzyme de l'aldh Active FR3054564B1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR1657324A FR3054564B1 (fr) 2016-07-28 2016-07-28 Substrat specifique d'une isoenzyme de l'aldh
JP2019503937A JP7050748B2 (ja) 2016-07-28 2017-07-27 Aldhアイソザイムの特異的基質
CA3031587A CA3031587A1 (fr) 2016-07-28 2017-07-27 Substrat specifique d'une isoenzyme de l'aldh
PCT/EP2017/068985 WO2018019927A1 (fr) 2016-07-28 2017-07-27 Substrat spécifique d'une isoenzyme de l'aldh
EP17749666.8A EP3491143A1 (fr) 2016-07-28 2017-07-27 Substrat spécifique d'une isoenzyme de l'aldh
CN201780057477.5A CN109715822A (zh) 2016-07-28 2017-07-27 Aldh同工酶的特异性底物
US16/320,071 US11519014B2 (en) 2016-07-28 2017-07-27 Specific substrate of an ALDH isoenzyme
IL264481A IL264481B1 (en) 2016-07-28 2017-07-27 Specific substrate of ALDH isoenzyme

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1657324 2016-07-28
FR1657324A FR3054564B1 (fr) 2016-07-28 2016-07-28 Substrat specifique d'une isoenzyme de l'aldh

Publications (2)

Publication Number Publication Date
FR3054564A1 FR3054564A1 (fr) 2018-02-02
FR3054564B1 true FR3054564B1 (fr) 2018-08-31

Family

ID=57583191

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1657324A Active FR3054564B1 (fr) 2016-07-28 2016-07-28 Substrat specifique d'une isoenzyme de l'aldh

Country Status (8)

Country Link
US (1) US11519014B2 (fr)
EP (1) EP3491143A1 (fr)
JP (1) JP7050748B2 (fr)
CN (1) CN109715822A (fr)
CA (1) CA3031587A1 (fr)
FR (1) FR3054564B1 (fr)
IL (1) IL264481B1 (fr)
WO (1) WO2018019927A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116609525B (zh) * 2023-05-26 2023-10-27 杭州圣域生物医药科技有限公司 基于细胞内aldh3b1蛋白水平以筛选染色质重塑复合体抑制剂的方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3378463A (en) * 1965-06-22 1968-04-16 Army Usa Method of measuring enzyme activity
FR2707665A1 (fr) 1993-06-28 1995-01-20 Chemunex Procédé de mesure et d'évaluation de la vitalité des microorganismes et ses applications.
CN1179108A (zh) * 1995-02-02 1998-04-15 耐克麦德英梅金公司 基于光透射、反射的体内成像用造影剂
NZ337946A (en) * 1998-09-25 2001-11-30 Tokyo Gas Co Ltd C-13 labelled oligosaccharides and polysaccharides useful as diagnostic agents for pancreatic exocrine function
WO2000034507A1 (fr) * 1998-12-07 2000-06-15 Duke University Methode d'isolation de cellules souches
EP2126574B1 (fr) * 2007-03-08 2015-12-23 The Board of Trustees of the Leland Stanford Junior University Modulateurs de l'aldéhyde deshydrogènase-2 mitochondrial, et leurs procédés d'utilisation
JP2009062300A (ja) * 2007-09-05 2009-03-26 Sumitomo Chemical Co Ltd クマリン化合物及びその用途
US8354435B2 (en) * 2008-09-08 2013-01-15 The Board Of Trustees Of The Leland Stanford Junior University Modulators of aldehyde dehydrogenase activity and methods of use thereof
GB0819280D0 (en) 2008-10-21 2008-11-26 Gen Electric Imgaing and radiotherapy methods
CN102202669A (zh) 2008-10-28 2011-09-28 利兰·斯坦福青年大学托管委员会 醛脱氢酶调节剂及其使用方法
JP2011184303A (ja) * 2010-03-04 2011-09-22 Univ Of Tsukuba 骨再生促進剤の製造方法
US9051597B2 (en) * 2010-05-25 2015-06-09 Mitsubishi Rayon Co., Ltd. Fluorescent substrate for detection of enzymatic activity of nitrile-related enzyme
US20120237931A1 (en) * 2011-03-14 2012-09-20 Katz Ruth L Identification and monitoring of circulating cancer stem cells
US10156521B2 (en) * 2013-02-21 2018-12-18 The Johns Hopkins University Red fluorescent aldehyde dehydrogenase (ALDH) substrate

Also Published As

Publication number Publication date
IL264481B1 (en) 2024-05-01
FR3054564A1 (fr) 2018-02-02
EP3491143A1 (fr) 2019-06-05
CA3031587A1 (fr) 2018-02-01
WO2018019927A1 (fr) 2018-02-01
US20190233871A1 (en) 2019-08-01
CN109715822A (zh) 2019-05-03
JP7050748B2 (ja) 2022-04-08
IL264481A (en) 2019-02-28
US11519014B2 (en) 2022-12-06
JP2019525762A (ja) 2019-09-12

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