FR3022245B1 - Derives de 3,5-dihydro-2h-pyrazolo[4,3-c]pyridin-3-one et leur utilisation - Google Patents

Derives de 3,5-dihydro-2h-pyrazolo[4,3-c]pyridin-3-one et leur utilisation

Info

Publication number
FR3022245B1
FR3022245B1 FR1455322A FR1455322A FR3022245B1 FR 3022245 B1 FR3022245 B1 FR 3022245B1 FR 1455322 A FR1455322 A FR 1455322A FR 1455322 A FR1455322 A FR 1455322A FR 3022245 B1 FR3022245 B1 FR 3022245B1
Authority
FR
France
Prior art keywords
pyrazolo
pyridin
dihydro
derivatives
medicaments
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1455322A
Other languages
English (en)
Other versions
FR3022245A1 (fr
Inventor
Regis Millet
Philippe Chavatte
Pierre Desreumaux
Mathilde Body
Bakali Jamal El
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Du Droit Et de la Sante Lille 2, University of
Universite Lille 2 Droit et Sante
Institut National de la Sante et de la Recherche Medicale INSERM
Centre Hospitalier Universitaire de Lille CHU
Original Assignee
Du Droit Et de la Sante Lille 2, University of
Universite Lille 2 Droit et Sante
Institut National de la Sante et de la Recherche Medicale INSERM
Centre Hospitalier Regional Universitaire de Lille CHRU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Droit Et de la Sante Lille 2, University of, Universite Lille 2 Droit et Sante, Institut National de la Sante et de la Recherche Medicale INSERM, Centre Hospitalier Regional Universitaire de Lille CHRU filed Critical Du Droit Et de la Sante Lille 2, University of
Priority to FR1455322A priority Critical patent/FR3022245B1/fr
Priority to CA2950853A priority patent/CA2950853A1/fr
Priority to US15/317,827 priority patent/US20170137419A1/en
Priority to PCT/FR2015/051549 priority patent/WO2015189523A1/fr
Priority to EP15732863.4A priority patent/EP3154981A1/fr
Publication of FR3022245A1 publication Critical patent/FR3022245A1/fr
Application granted granted Critical
Publication of FR3022245B1 publication Critical patent/FR3022245B1/fr
Priority to IL249307A priority patent/IL249307A0/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des composés de Formule I : ou leurs solvates pharmaceutiquement acceptables, ainsi que leur utilisation en tant que médicament.
FR1455322A 2014-06-12 2014-06-12 Derives de 3,5-dihydro-2h-pyrazolo[4,3-c]pyridin-3-one et leur utilisation Active FR3022245B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR1455322A FR3022245B1 (fr) 2014-06-12 2014-06-12 Derives de 3,5-dihydro-2h-pyrazolo[4,3-c]pyridin-3-one et leur utilisation
CA2950853A CA2950853A1 (fr) 2014-06-12 2015-06-11 Derives de 2h-pyrazolo[4,3-c]quinolin-3(5h)-one et leur utilisation
US15/317,827 US20170137419A1 (en) 2014-06-12 2015-06-11 Derivatives of 2h-pyrazolo[4,3-c]quinolin-3(5h)-one and use thereof
PCT/FR2015/051549 WO2015189523A1 (fr) 2014-06-12 2015-06-11 Derives de 2h-pyrazolo[4,3-c]quinolin-3(5h)-one et leur utilisation
EP15732863.4A EP3154981A1 (fr) 2014-06-12 2015-06-11 Dérivés de 2h-pyrazolo [ 4,3-c ] quinolin-3-one et son utilisation (5h)
IL249307A IL249307A0 (en) 2014-06-12 2016-11-30 History of h2-pyrazolo[3,4-c]quinolin-3(h5)-one and their use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1455322A FR3022245B1 (fr) 2014-06-12 2014-06-12 Derives de 3,5-dihydro-2h-pyrazolo[4,3-c]pyridin-3-one et leur utilisation

Publications (2)

Publication Number Publication Date
FR3022245A1 FR3022245A1 (fr) 2015-12-18
FR3022245B1 true FR3022245B1 (fr) 2016-07-01

Family

ID=51570576

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1455322A Active FR3022245B1 (fr) 2014-06-12 2014-06-12 Derives de 3,5-dihydro-2h-pyrazolo[4,3-c]pyridin-3-one et leur utilisation

Country Status (6)

Country Link
US (1) US20170137419A1 (fr)
EP (1) EP3154981A1 (fr)
CA (1) CA2950853A1 (fr)
FR (1) FR3022245B1 (fr)
IL (1) IL249307A0 (fr)
WO (1) WO2015189523A1 (fr)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2261211A1 (fr) 2009-05-20 2010-12-15 Université de Lille 2 Droit et Santé Dérivés de 1,4-dihydropyridine et leurs utilisations
WO2011049731A1 (fr) * 2009-10-21 2011-04-28 Merck Sharp & Dohme Corp. Composés de quinoléinone-pyrazolone modulateurs allostériques positifs du récepteur m1

Also Published As

Publication number Publication date
WO2015189523A1 (fr) 2015-12-17
US20170137419A1 (en) 2017-05-18
EP3154981A1 (fr) 2017-04-19
FR3022245A1 (fr) 2015-12-18
IL249307A0 (en) 2017-02-28
CA2950853A1 (fr) 2015-12-17

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