FR2873374B1 - Derives d'acylaminothiazole, leur preparation et leur application en therapeutique - Google Patents

Derives d'acylaminothiazole, leur preparation et leur application en therapeutique

Info

Publication number
FR2873374B1
FR2873374B1 FR0408116A FR0408116A FR2873374B1 FR 2873374 B1 FR2873374 B1 FR 2873374B1 FR 0408116 A FR0408116 A FR 0408116A FR 0408116 A FR0408116 A FR 0408116A FR 2873374 B1 FR2873374 B1 FR 2873374B1
Authority
FR
France
Prior art keywords
preparation
therapeutic application
acylaminothiazole derivatives
acylaminothiazole
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0408116A
Other languages
English (en)
Other versions
FR2873374A1 (fr
Inventor
Sylvie Baltzer
Marc Pascal
Dorsselaer Viviane Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0408116A priority Critical patent/FR2873374B1/fr
Application filed by Sanofi Synthelabo SA filed Critical Sanofi Synthelabo SA
Priority to SI200531394T priority patent/SI1709018T1/sl
Priority to AT05717377T priority patent/ATE517098T1/de
Priority to DK05717377.5T priority patent/DK1709018T3/da
Priority to JP2006548340A priority patent/JP4813371B2/ja
Priority to PT05717377T priority patent/PT1709018E/pt
Priority to EP05717377A priority patent/EP1709018B1/fr
Priority to PCT/FR2005/000029 priority patent/WO2005073202A1/fr
Priority to TW094100684A priority patent/TWI350287B/zh
Priority to ARP050100110A priority patent/AR047383A1/es
Publication of FR2873374A1 publication Critical patent/FR2873374A1/fr
Priority to IL176772A priority patent/IL176772A0/en
Priority to US11/457,490 priority patent/US7371770B2/en
Application granted granted Critical
Publication of FR2873374B1 publication Critical patent/FR2873374B1/fr
Priority to US12/051,924 priority patent/US7759377B2/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR0408116A 2004-01-16 2004-07-22 Derives d'acylaminothiazole, leur preparation et leur application en therapeutique Expired - Fee Related FR2873374B1 (fr)

Priority Applications (13)

Application Number Priority Date Filing Date Title
FR0408116A FR2873374B1 (fr) 2004-07-22 2004-07-22 Derives d'acylaminothiazole, leur preparation et leur application en therapeutique
EP05717377A EP1709018B1 (fr) 2004-01-16 2005-01-07 Derives d'acylaminothiazole et leur application comme inhibiteurs de beta-amyloide
AT05717377T ATE517098T1 (de) 2004-01-16 2005-01-07 Acylaminothiazolderivate und deren verwendung als beta-amyloid-inhibitoren
DK05717377.5T DK1709018T3 (da) 2004-01-16 2005-01-07 Acylaminothiazolderivater og anvendelse deraf som beta-amyloid-hæmmere
JP2006548340A JP4813371B2 (ja) 2004-01-16 2005-01-07 アシルアミノチアゾール誘導体及びβ−アミロイド阻害剤としてのこれらの使用
PT05717377T PT1709018E (pt) 2004-01-16 2005-01-07 Derivados de acilaminotiazole e sua aplicação como inibidores
SI200531394T SI1709018T1 (sl) 2004-01-16 2005-01-07 Acilaminotiazolni derivati in njihova uporaba kotbeta-amiloidni inhibitorji
PCT/FR2005/000029 WO2005073202A1 (fr) 2004-01-16 2005-01-07 Derives d’acylaminothiazole et leur application comme inhibiteurs de beta-amyloide
TW094100684A TWI350287B (en) 2004-01-16 2005-01-11 Acylaminothiazole derivatives, their preparation and their therapeutic application
ARP050100110A AR047383A1 (es) 2004-01-16 2005-01-13 Derivados de acilaminotiazol, su preparacion y su aplicacion en terapeutica
IL176772A IL176772A0 (en) 2004-01-16 2006-07-10 Acylaminothiazole derivatives and use thereof as beta-amyloid inhibitors
US11/457,490 US7371770B2 (en) 2004-01-16 2006-07-14 Acylaminothiazole derivatives and use thereof as β-amyloid inhibitors
US12/051,924 US7759377B2 (en) 2004-01-16 2008-03-20 Acylaminothiazole derivatives and use thereof as beta-amyloid inhibitors

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0408116A FR2873374B1 (fr) 2004-07-22 2004-07-22 Derives d'acylaminothiazole, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
FR2873374A1 FR2873374A1 (fr) 2006-01-27
FR2873374B1 true FR2873374B1 (fr) 2006-10-20

Family

ID=34950305

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0408116A Expired - Fee Related FR2873374B1 (fr) 2004-01-16 2004-07-22 Derives d'acylaminothiazole, leur preparation et leur application en therapeutique

Country Status (1)

Country Link
FR (1) FR2873374B1 (fr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2840899B1 (fr) * 2002-06-12 2005-02-25 Sanofi Synthelabo Derives d'acylaminothiazole, leur preparation et leur utilisation en therapeutique
AR039059A1 (es) * 2001-08-06 2005-02-09 Sanofi Aventis Compuesto derivado de acilaminotiazol, su utilizacion, procedimientos para prepararlo, composicion farmaceutica que lo comprende, y compuestos intermediarios
WO2004033439A1 (fr) * 2002-10-09 2004-04-22 Pfizer Products Inc. Composes thiazole utiles pour le traitement des maladies neurodegeneratives

Also Published As

Publication number Publication date
FR2873374A1 (fr) 2006-01-27

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Legal Events

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CD Change of name or company name
ST Notification of lapse

Effective date: 20130329