FR2854399A1 - 1-aryl-3-(indol-5-yl)-prop-2-en-1-ones, compositions les contenant et utilisation - Google Patents
1-aryl-3-(indol-5-yl)-prop-2-en-1-ones, compositions les contenant et utilisationInfo
- Publication number
- FR2854399A1 FR2854399A1 FR0305389A FR0305389A FR2854399A1 FR 2854399 A1 FR2854399 A1 FR 2854399A1 FR 0305389 A FR0305389 A FR 0305389A FR 0305389 A FR0305389 A FR 0305389A FR 2854399 A1 FR2854399 A1 FR 2854399A1
- Authority
- FR
- France
- Prior art keywords
- indol
- prop
- aryl
- ones
- compositions containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
1-Aryl-3-(indol-5-yl)-prop-2-èn-1-ones, compositions les contenant et utilisation. La présente invention concerne notamment de nouvelles 1-aryl-3-(indol-5-yl)-prop-2-èn-1-ones substituées ayant une activité thérapeutique, utilisables en particulier en oncologie.
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0305389A FR2854399B1 (fr) | 2003-04-30 | 2003-04-30 | 1-aryl-3-(indol-5-yl)-prop-2-en-1-ones, compositions les contenant et utilisation |
PCT/FR2004/001012 WO2004099193A2 (fr) | 2003-04-30 | 2004-04-27 | 1-aryl-3-(indol-5-yl)-prop-2-en-1-ones, compositions les contenant et utilisation |
EP04742579A EP1622895A2 (fr) | 2003-04-30 | 2004-04-27 | 1-aryl-3-(indol-5-yl)-prop-2-en-1-ones, compositions les contenant et utilisation |
JP2006505814A JP2006525291A (ja) | 2003-04-30 | 2004-04-27 | 1−アリール−3−(インドール−5−イル)プロパ−2−エン−1−オン、該化合物を含む組成物、及びそれらの使用 |
US10/835,631 US20040229931A1 (en) | 2003-04-30 | 2004-04-30 | 1-Aryl-3-(indol-5-yl) prop-2-en-1-ones, compositions containing them and use |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0305389A FR2854399B1 (fr) | 2003-04-30 | 2003-04-30 | 1-aryl-3-(indol-5-yl)-prop-2-en-1-ones, compositions les contenant et utilisation |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2854399A1 true FR2854399A1 (fr) | 2004-11-05 |
FR2854399B1 FR2854399B1 (fr) | 2006-11-17 |
Family
ID=33155601
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0305389A Expired - Lifetime FR2854399B1 (fr) | 2003-04-30 | 2003-04-30 | 1-aryl-3-(indol-5-yl)-prop-2-en-1-ones, compositions les contenant et utilisation |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1622895A2 (fr) |
JP (1) | JP2006525291A (fr) |
FR (1) | FR2854399B1 (fr) |
WO (1) | WO2004099193A2 (fr) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0680950A1 (fr) * | 1993-11-17 | 1995-11-08 | Kyowa Hakko Kogyo Co., Ltd. | Derive de propenone |
EP0770601A1 (fr) * | 1995-05-10 | 1997-05-02 | Kyowa Hakko Kogyo Co., Ltd. | Derives de propenone |
WO2003048106A2 (fr) * | 2001-12-05 | 2003-06-12 | Aventis Pharma S.A. | 1,3-diarylprop-2-en-1-ones, compositions les contenant et utilisation |
-
2003
- 2003-04-30 FR FR0305389A patent/FR2854399B1/fr not_active Expired - Lifetime
-
2004
- 2004-04-27 JP JP2006505814A patent/JP2006525291A/ja active Pending
- 2004-04-27 EP EP04742579A patent/EP1622895A2/fr not_active Withdrawn
- 2004-04-27 WO PCT/FR2004/001012 patent/WO2004099193A2/fr not_active Application Discontinuation
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0680950A1 (fr) * | 1993-11-17 | 1995-11-08 | Kyowa Hakko Kogyo Co., Ltd. | Derive de propenone |
EP0770601A1 (fr) * | 1995-05-10 | 1997-05-02 | Kyowa Hakko Kogyo Co., Ltd. | Derives de propenone |
WO2003048106A2 (fr) * | 2001-12-05 | 2003-06-12 | Aventis Pharma S.A. | 1,3-diarylprop-2-en-1-ones, compositions les contenant et utilisation |
Non-Patent Citations (1)
Title |
---|
BECKERS ET AL.: "2-Aroylindoles, a Novel Class of Potent, Orally Active Small Molecule Tubulin Inhibitors", CANCER RESEARCH, vol. 62, 1 June 2002 (2002-06-01), pages 3113 - 3119, XP002267118 * |
Also Published As
Publication number | Publication date |
---|---|
FR2854399B1 (fr) | 2006-11-17 |
WO2004099193A2 (fr) | 2004-11-18 |
WO2004099193A3 (fr) | 2005-01-06 |
JP2006525291A (ja) | 2006-11-09 |
EP1622895A2 (fr) | 2006-02-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA28664B1 (fr) | Indazoles substitues, compositions les contenant, procede de fabrication et utilisation | |
ATE387435T1 (de) | Substituirte benzosulfonamide als potenzierungsmittel von glutamatrezeptoren | |
YU9404A (sh) | Multimerna, usmerena kontrastna sredstva na bazi peptida | |
RS50660B (sr) | Dihidrotetrabenazini i farmaceutske kompozicije koje ih sadrže | |
TNSN04175A1 (fr) | Indazoles substitues avec une activite anticancereuse | |
TR200102029T2 (tr) | 1-Heterosiklil ikameli diarilaminler. | |
SE0301653D0 (sv) | Novel compounds | |
EA200100731A1 (ru) | Фенилфенантридины с ингибирующей фдэ-4 активностью | |
ATE348616T1 (de) | 2-hydroxy-6-phenylphenanthridine als pde-4-hemmer | |
MXPA03007527A (es) | Enzimas que tienen actividad de alfa amilasa y metodos de uso de las mismas. | |
ATE353217T1 (de) | 3-hydroxy-6-phenylphenanthridine als pde-4 inhibitoren | |
BRPI0512235A (pt) | polipeptìdeos ligadores de antìgenos e seus usos | |
TW200519110A (en) | Substituted tetrahydro-1H-pyrazolo [3, 4-c] pyridines, compositions comprising them, and use | |
BRPI0507118A (pt) | polipeptìdeos de interferon humano modificado e seus usos | |
SE0301700D0 (sv) | Novel compounds | |
DE60230890D1 (de) | Indolizine als kinaseproteinhemmer | |
BRPI0409367A (pt) | derivados de piperidina inibidores de renina | |
DE602005017753D1 (de) | Mittel für die transdermale verabreichung von nikotin | |
DE602004006433D1 (de) | Pyrrol-substituierte indole als inhibitoren von pai-1 | |
EA200602137A1 (ru) | Гидрогелевые препараты интерферона | |
BRPI0413449A (pt) | compostos de quinoxalina | |
ATE425982T1 (de) | Thienopyrimidin-derivate als kaliumkanal- inhibitoren | |
PT1147103E (pt) | Fenantridina-n-oxidos com actividade inibitoria de pde-iv | |
TW200531686A (en) | Pharmaceutical compositions | |
UY3450Q (es) | Botella |