FR2847897B1 - Procede de preparation de diasteroisomeres et d'enantiomeres de la 4-hydroxyisoleucine et de ses derives - Google Patents

Procede de preparation de diasteroisomeres et d'enantiomeres de la 4-hydroxyisoleucine et de ses derives

Info

Publication number
FR2847897B1
FR2847897B1 FR0215165A FR0215165A FR2847897B1 FR 2847897 B1 FR2847897 B1 FR 2847897B1 FR 0215165 A FR0215165 A FR 0215165A FR 0215165 A FR0215165 A FR 0215165A FR 2847897 B1 FR2847897 B1 FR 2847897B1
Authority
FR
France
Prior art keywords
hydroxyisoleucine
diasteroisomers
enantiomers
derivatives
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0215165A
Other languages
English (en)
Other versions
FR2847897A1 (fr
Inventor
Charles Mioskowski
Alain Wagner
Lamo Marin Sandra De
Cedric Catala
Jean Michel Becht
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Universite Louis Pasteur Strasbourg I
Original Assignee
Centre National de la Recherche Scientifique CNRS
Universite Louis Pasteur Strasbourg I
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0215165A priority Critical patent/FR2847897B1/fr
Application filed by Centre National de la Recherche Scientifique CNRS, Universite Louis Pasteur Strasbourg I filed Critical Centre National de la Recherche Scientifique CNRS
Priority to US10/537,293 priority patent/US7420087B2/en
Priority to CNB2003801081665A priority patent/CN100564352C/zh
Priority to JP2004558145A priority patent/JP2006508168A/ja
Priority to EP03796121A priority patent/EP1572623A1/fr
Priority to PCT/FR2003/003542 priority patent/WO2004052836A1/fr
Priority to CA002507669A priority patent/CA2507669A1/fr
Priority to AU2003298380A priority patent/AU2003298380B2/en
Publication of FR2847897A1 publication Critical patent/FR2847897A1/fr
Application granted granted Critical
Publication of FR2847897B1 publication Critical patent/FR2847897B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/66—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C07C227/32—Preparation of optical isomers by stereospecific synthesis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FR0215165A 2002-12-02 2002-12-02 Procede de preparation de diasteroisomeres et d'enantiomeres de la 4-hydroxyisoleucine et de ses derives Expired - Fee Related FR2847897B1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR0215165A FR2847897B1 (fr) 2002-12-02 2002-12-02 Procede de preparation de diasteroisomeres et d'enantiomeres de la 4-hydroxyisoleucine et de ses derives
CNB2003801081665A CN100564352C (zh) 2002-12-02 2003-12-01 4-羟基异亮氨酸的非对映异构体和对映异构体及其衍生物的制备方法
JP2004558145A JP2006508168A (ja) 2002-12-02 2003-12-01 ４−ヒドロキシイソロイシン及びその誘導体のジアステレオ異性体及びエナンチオマーの製造方法
EP03796121A EP1572623A1 (fr) 2002-12-02 2003-12-01 Procede de preparation de diastereoisomeres et d 'enantiomeres de la 4-hydroxyisoleucine et de ses derives
US10/537,293 US7420087B2 (en) 2002-12-02 2003-12-01 Method for preparing 4-hydroxyisoleucine diastereoisomers and enantiomers and derivatives thereof
PCT/FR2003/003542 WO2004052836A1 (fr) 2002-12-02 2003-12-01 Procede de preparation de diastereoisomeres et d'enantiomeres de la 4-hydroxyisoleucine et de ses derives
CA002507669A CA2507669A1 (fr) 2002-12-02 2003-12-01 Procede de preparation de diastereoisomeres et d'enantiomeres de la 4-hydroxyisoleucine et de ses derives
AU2003298380A AU2003298380B2 (en) 2002-12-02 2003-12-01 Method for preparing 4-hydroxyisoleucine diastereoisomers and enantiomers and derivatives thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0215165A FR2847897B1 (fr) 2002-12-02 2002-12-02 Procede de preparation de diasteroisomeres et d'enantiomeres de la 4-hydroxyisoleucine et de ses derives

Publications (2)

Publication Number Publication Date
FR2847897A1 FR2847897A1 (fr) 2004-06-04
FR2847897B1 true FR2847897B1 (fr) 2006-02-24

Family

ID=32309925

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0215165A Expired - Fee Related FR2847897B1 (fr) 2002-12-02 2002-12-02 Procede de preparation de diasteroisomeres et d'enantiomeres de la 4-hydroxyisoleucine et de ses derives

Country Status (8)

Country Link
US (1) US7420087B2 (fr)
EP (1) EP1572623A1 (fr)
JP (1) JP2006508168A (fr)
CN (1) CN100564352C (fr)
AU (1) AU2003298380B2 (fr)
CA (1) CA2507669A1 (fr)
FR (1) FR2847897B1 (fr)
WO (1) WO2004052836A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007105650A1 (fr) * 2006-03-10 2007-09-20 Ajinomoto Co., Inc. Derive 4-hydroxyisoleucine et son procede de production
WO2008154743A1 (fr) * 2007-06-19 2008-12-24 Innodia Inc. Procédés de synthèse de la 4-hydroxyisoleucine, de ses stéréoisomères et de ses analogues
JP2011507890A (ja) * 2007-12-20 2011-03-10 ドクター・レディーズ・ラボラトリーズ・リミテッド シタグリプチンおよびその薬学的に許容可能な塩の調製のためのプロセス

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5900237A (en) * 1983-11-29 1999-05-04 Igen International, Inc. Catalytic antibodies which hydrolyze primary amides and methods for eliciting such antibodies
JPH06306053A (ja) * 1993-01-29 1994-11-01 Sagami Chem Res Center ３−アゾールカルボン酸誘導体の製造方法及びその中間体
US5763483A (en) * 1995-12-29 1998-06-09 Gilead Sciences, Inc. Carbocyclic compounds
WO1999054297A1 (fr) * 1998-04-16 1999-10-28 Nagase & Company, Ltd. Procede de preparation de chloroalcools et de leurs intermediaires
FR2797767B1 (fr) * 1999-08-27 2002-06-14 Centre Nat Rech Scient Utilisation d'acides amines pour la fabrication de medicaments destines au traitement des insulino-resistances

Also Published As

Publication number Publication date
JP2006508168A (ja) 2006-03-09
FR2847897A1 (fr) 2004-06-04
AU2003298380A1 (en) 2004-06-30
CA2507669A1 (fr) 2004-06-24
AU2003298380B2 (en) 2010-11-11
US7420087B2 (en) 2008-09-02
US20060205817A1 (en) 2006-09-14
WO2004052836A1 (fr) 2004-06-24
AU2003298380A8 (en) 2004-06-30
EP1572623A1 (fr) 2005-09-14
CN1735589A (zh) 2006-02-15
CN100564352C (zh) 2009-12-02

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Legal Events

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Effective date: 20120831