FR2800736B1 - Derives d'oligobenzimidazoles, les compositions les contenant et leurs utilisations - Google Patents

Derives d'oligobenzimidazoles, les compositions les contenant et leurs utilisations

Info

Publication number
FR2800736B1
FR2800736B1 FR9913934A FR9913934A FR2800736B1 FR 2800736 B1 FR2800736 B1 FR 2800736B1 FR 9913934 A FR9913934 A FR 9913934A FR 9913934 A FR9913934 A FR 9913934A FR 2800736 B1 FR2800736 B1 FR 2800736B1
Authority
FR
France
Prior art keywords
oligobenzimidazoles
derivatives
compositions containing
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9913934A
Other languages
English (en)
Other versions
FR2800736A1 (fr
Inventor
Daniel Scherman
Michel Bessodes
Bruno Pitard
Javier Soto
Gerardo Byk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9913934A priority Critical patent/FR2800736B1/fr
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Priority to CA002389778A priority patent/CA2389778A1/fr
Priority to EP00976109A priority patent/EP1230223B1/fr
Priority to IL14915300A priority patent/IL149153A0/xx
Priority to PCT/FR2000/003087 priority patent/WO2001032630A1/fr
Priority to PT00976109T priority patent/PT1230223E/pt
Priority to DE60008573T priority patent/DE60008573T2/de
Priority to JP2001534781A priority patent/JP2003513078A/ja
Priority to AU13998/01A priority patent/AU1399801A/en
Priority to MXPA02004449A priority patent/MXPA02004449A/es
Priority to AT00976109T priority patent/ATE260261T1/de
Priority to DK00976109T priority patent/DK1230223T3/da
Priority to ES00976109T priority patent/ES2211644T3/es
Publication of FR2800736A1 publication Critical patent/FR2800736A1/fr
Priority to US10/139,549 priority patent/US20030105048A1/en
Application granted granted Critical
Publication of FR2800736B1 publication Critical patent/FR2800736B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/20—Two benzimidazolyl-2 radicals linked together directly or via a hydrocarbon or substituted hydrocarbon radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR9913934A 1999-11-05 1999-11-05 Derives d'oligobenzimidazoles, les compositions les contenant et leurs utilisations Expired - Fee Related FR2800736B1 (fr)

Priority Applications (14)

Application Number Priority Date Filing Date Title
FR9913934A FR2800736B1 (fr) 1999-11-05 1999-11-05 Derives d'oligobenzimidazoles, les compositions les contenant et leurs utilisations
AT00976109T ATE260261T1 (de) 1999-11-05 2000-11-06 Oligobenzimidazolderivate und ihre verwendung als dna-transfektionsmittel
IL14915300A IL149153A0 (en) 1999-11-05 2000-11-06 Oligobenzimidazole derivatives and their use as dna transfection agents
PCT/FR2000/003087 WO2001032630A1 (fr) 1999-11-05 2000-11-06 Derives d'oligobenzimidazoles et leur utilisation comme agents de transfection d'adn
PT00976109T PT1230223E (pt) 1999-11-05 2000-11-06 Derivados de oligobenzimidazoles e a sua utilizacao como agentes de transfeccao de adn
DE60008573T DE60008573T2 (de) 1999-11-05 2000-11-06 Oligobenzimidazolderivate und ihre verwendung als dna-transfektionsmittel
JP2001534781A JP2003513078A (ja) 1999-11-05 2000-11-06 オリゴベンズイミダゾール誘導体及びｄｎａ形質転換剤としてのそれらの使用
AU13998/01A AU1399801A (en) 1999-11-05 2000-11-06 Oligobenzimidazole derivatives and their use as dna transfection agents
CA002389778A CA2389778A1 (fr) 1999-11-05 2000-11-06 Derives d'oligobenzimidazoles et leur utilisation comme agents de transfection d'adn
EP00976109A EP1230223B1 (fr) 1999-11-05 2000-11-06 Derives d'oligobenzimidazoles et leur utilisation comme agents de transfection d'adn
DK00976109T DK1230223T3 (da) 1999-11-05 2000-11-06 Oligobenzimidazolderivater og deres anvendelse som midler til DNA-transfektion
ES00976109T ES2211644T3 (es) 1999-11-05 2000-11-06 Derivados de oligo bencimidazoles y su utilizacion como agentes de transfeccion del adn.
MXPA02004449A MXPA02004449A (es) 1999-11-05 2000-11-06 Derivados de oligobencimidazoles y su uso como agentes de transfeccion del acido desoxirribunucleico (adn)..
US10/139,549 US20030105048A1 (en) 1999-11-05 2002-05-06 Oligobenzimidazole derivatives and their use as DNA transfecting agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9913934A FR2800736B1 (fr) 1999-11-05 1999-11-05 Derives d'oligobenzimidazoles, les compositions les contenant et leurs utilisations

Publications (2)

Publication Number Publication Date
FR2800736A1 FR2800736A1 (fr) 2001-05-11
FR2800736B1 true FR2800736B1 (fr) 2002-08-23

Family

ID=9551799

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9913934A Expired - Fee Related FR2800736B1 (fr) 1999-11-05 1999-11-05 Derives d'oligobenzimidazoles, les compositions les contenant et leurs utilisations

Country Status (1)

Country Link
FR (1) FR2800736B1 (fr)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ207393A (en) * 1983-08-05 1987-03-31 Neal Lloyd First Staining dna in living cells
NZ239893A (en) * 1990-09-25 1993-11-25 Hoechst Japan A method for introducing a foreign dna into a cell

Also Published As

Publication number Publication date
FR2800736A1 (fr) 2001-05-11

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Legal Events

Date Code Title Description
ST Notification of lapse