FR2797398B1 - Microparticules pour administration pulmonaire - Google Patents

Microparticules pour administration pulmonaire

Info

Publication number
FR2797398B1
FR2797398B1 FR9910411A FR9910411A FR2797398B1 FR 2797398 B1 FR2797398 B1 FR 2797398B1 FR 9910411 A FR9910411 A FR 9910411A FR 9910411 A FR9910411 A FR 9910411A FR 2797398 B1 FR2797398 B1 FR 2797398B1
Authority
FR
France
Prior art keywords
microparticles
pulmonary administration
pulmonary
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9910411A
Other languages
English (en)
Other versions
FR2797398A1 (fr
Inventor
Joel Richard
Claire Dulieu
Meurlay Dominique Le
Jean Pierre Benoit
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mainelab SA
Original Assignee
Mainelab SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9910411A priority Critical patent/FR2797398B1/fr
Application filed by Mainelab SA filed Critical Mainelab SA
Priority to JP2001516507A priority patent/JP2003506479A/ja
Priority to IL14806300A priority patent/IL148063A0/xx
Priority to HU0202545A priority patent/HUP0202545A3/hu
Priority to AU70104/00A priority patent/AU784168B2/en
Priority to PCT/FR2000/002282 priority patent/WO2001012160A1/fr
Priority to CA002380883A priority patent/CA2380883A1/fr
Priority to EP00958655A priority patent/EP1204409A1/fr
Priority to MXPA02001520A priority patent/MXPA02001520A/es
Priority to CNB008116660A priority patent/CN1220484C/zh
Priority to KR1020027001717A priority patent/KR20020038719A/ko
Publication of FR2797398A1 publication Critical patent/FR2797398A1/fr
Priority to NO20020555A priority patent/NO20020555L/no
Priority to ZA200201109A priority patent/ZA200201109B/en
Application granted granted Critical
Publication of FR2797398B1 publication Critical patent/FR2797398B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A61P5/22—Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of calcitonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Otolaryngology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR9910411A 1999-08-11 1999-08-11 Microparticules pour administration pulmonaire Expired - Lifetime FR2797398B1 (fr)

Priority Applications (13)

Application Number Priority Date Filing Date Title
FR9910411A FR2797398B1 (fr) 1999-08-11 1999-08-11 Microparticules pour administration pulmonaire
KR1020027001717A KR20020038719A (ko) 1999-08-11 2000-08-09 폐 투여용 미립자
HU0202545A HUP0202545A3 (en) 1999-08-11 2000-08-09 Microparticles for pulmonary administration
AU70104/00A AU784168B2 (en) 1999-08-11 2000-08-09 Microparticles for pulmonary administration
PCT/FR2000/002282 WO2001012160A1 (fr) 1999-08-11 2000-08-09 Microparticules pour administration pulmonaire
CA002380883A CA2380883A1 (fr) 1999-08-11 2000-08-09 Microparticules pour administration pulmonaire
JP2001516507A JP2003506479A (ja) 1999-08-11 2000-08-09 肺への投与用の微粒子
MXPA02001520A MXPA02001520A (es) 1999-08-11 2000-08-09 Microparticulas para administracion pulmonar.
CNB008116660A CN1220484C (zh) 1999-08-11 2000-08-09 用于肺部给药的微颗粒
IL14806300A IL148063A0 (en) 1999-08-11 2000-08-09 Microparticles for pulmonary administration
EP00958655A EP1204409A1 (fr) 1999-08-11 2000-08-09 Microparticules pour administration pulmonaire
NO20020555A NO20020555L (no) 1999-08-11 2002-02-04 Mikropartikler for lungeadministrering
ZA200201109A ZA200201109B (en) 1999-08-11 2002-02-08 Microparticles for pulmonary administration.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9910411A FR2797398B1 (fr) 1999-08-11 1999-08-11 Microparticules pour administration pulmonaire

Publications (2)

Publication Number Publication Date
FR2797398A1 FR2797398A1 (fr) 2001-02-16
FR2797398B1 true FR2797398B1 (fr) 2002-10-18

Family

ID=9549086

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9910411A Expired - Lifetime FR2797398B1 (fr) 1999-08-11 1999-08-11 Microparticules pour administration pulmonaire

Country Status (13)

Country Link
EP (1) EP1204409A1 (fr)
JP (1) JP2003506479A (fr)
KR (1) KR20020038719A (fr)
CN (1) CN1220484C (fr)
AU (1) AU784168B2 (fr)
CA (1) CA2380883A1 (fr)
FR (1) FR2797398B1 (fr)
HU (1) HUP0202545A3 (fr)
IL (1) IL148063A0 (fr)
MX (1) MXPA02001520A (fr)
NO (1) NO20020555L (fr)
WO (1) WO2001012160A1 (fr)
ZA (1) ZA200201109B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2809309B1 (fr) * 2000-05-23 2004-06-11 Mainelab Microspheres a liberation prolongee pour administration injectable
WO2003077891A1 (fr) * 2002-03-18 2003-09-25 Yamanouchi Pharmaceutical Co., Ltd. Compositions medicales en poudre pour inhalation et procede de production de celles-ci
JP2005279334A (ja) * 2004-03-26 2005-10-13 Kao Corp 複合化粒子の製造方法
EP1904219A4 (fr) 2005-07-15 2011-07-27 Map Pharmaceuticals Inc Procede de formation de particules
EP1757361A1 (fr) * 2005-08-23 2007-02-28 Feyecon Development & Implementation B.V. Procédé de préparation d'encapsulations par précipitation
CN101143131B (zh) * 2006-09-15 2012-03-07 国家纳米技术与工程研究院 一种利用超临界流体技术制备人胰岛素吸入干粉的方法
US20100034888A1 (en) * 2006-09-15 2010-02-11 Hubert Clemens Pellikaan Granulate containing a pharmaceutically active substance and method for its manufacture
EP2131903B1 (fr) * 2007-03-23 2018-01-24 Geno LLC Conversion du dioxyde d'azote (no2) en oxyde nitrique (no)
KR101102834B1 (ko) * 2010-02-24 2012-01-05 충남대학교산학협력단 신규한 리포좀 제조 방법 및 장치
JP5672554B2 (ja) * 2010-08-19 2015-02-18 Ｊｃｒファーマ株式会社 皮下又は経皮吸収用組成物
CN102872027B (zh) * 2012-09-18 2014-03-12 刘晓忠 一种治疗肺部疾病的药物颗粒的制备和吸入式复方气雾剂的制备

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04222662A (ja) * 1990-12-25 1992-08-12 Nippon Steel Chem Co Ltd 固体表面へのポリマー皮膜形成方法
EP0706821A1 (fr) * 1994-10-06 1996-04-17 Centre De Microencapsulation Procédé pour l'enrobage de particules
ES2170853T3 (es) * 1995-03-28 2002-08-16 Fidia Advanced Biopolymers Srl Nanosferas que comprenden un polisacarido biocompatible.
FR2753639B1 (fr) * 1996-09-25 1998-12-11 Procede de preparation de microcapsules de matieres actives enrobees par un polymere et nouvelles microcapsules notamment obtenues selon le procede
US5766637A (en) * 1996-10-08 1998-06-16 University Of Delaware Microencapsulation process using supercritical fluids
CA2277801C (fr) * 1997-01-16 2002-10-15 Massachusetts Institute Of Technology Preparation de particules pour inhalation
JPH1147681A (ja) * 1997-08-05 1999-02-23 Kira Keshohin Kk 超臨界流体を用いた微粒子のコーティング方法及び塗装物
JPH11197494A (ja) * 1998-01-13 1999-07-27 Kenji Mishima 超臨界流体を用いた微小粒子コーティング

Also Published As

Publication number Publication date
IL148063A0 (en) 2002-09-12
WO2001012160A1 (fr) 2001-02-22
JP2003506479A (ja) 2003-02-18
HUP0202545A2 (hu) 2004-03-01
EP1204409A1 (fr) 2002-05-15
CA2380883A1 (fr) 2001-02-22
ZA200201109B (en) 2002-10-30
NO20020555L (no) 2002-04-09
AU784168B2 (en) 2006-02-16
CN1220484C (zh) 2005-09-28
HUP0202545A3 (en) 2004-05-28
AU7010400A (en) 2001-03-13
MXPA02001520A (es) 2003-07-21
FR2797398A1 (fr) 2001-02-16
NO20020555D0 (no) 2002-02-04
KR20020038719A (ko) 2002-05-23
CN1461211A (zh) 2003-12-10

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