FR2794649B1 - Biomateriau a base d'un derive de dextrane insolubilise et d'un facteur de croissance, son procede de preparation et ses applications - Google Patents

Biomateriau a base d'un derive de dextrane insolubilise et d'un facteur de croissance, son procede de preparation et ses applications

Info

Publication number
FR2794649B1
FR2794649B1 FR9907401A FR9907401A FR2794649B1 FR 2794649 B1 FR2794649 B1 FR 2794649B1 FR 9907401 A FR9907401 A FR 9907401A FR 9907401 A FR9907401 A FR 9907401A FR 2794649 B1 FR2794649 B1 FR 2794649B1
Authority
FR
France
Prior art keywords
applications
growth factor
preparing same
dextran derivative
biomaterial based
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9907401A
Other languages
English (en)
Other versions
FR2794649A1 (fr
Inventor
Cinderella Blanchat
Avramoglou Delphine Logeart
Herve Petite
Alain Meunier
Frederic Chaubet
Jacqueline Jozefonvicz
Marcel Jozefowicz
Laurent Sedel
Jose Correia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Solutions
Original Assignee
Solutions
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solutions filed Critical Solutions
Priority to FR9907401A priority Critical patent/FR2794649B1/fr
Priority to PCT/FR2000/001603 priority patent/WO2000076562A1/fr
Priority to CA002376898A priority patent/CA2376898A1/fr
Priority to JP2001502893A priority patent/JP2003501217A/ja
Priority to EP00940481A priority patent/EP1189644A1/fr
Publication of FR2794649A1 publication Critical patent/FR2794649A1/fr
Priority to US10/016,706 priority patent/US6946443B2/en
Application granted granted Critical
Publication of FR2794649B1 publication Critical patent/FR2794649B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Dental Preparations (AREA)
FR9907401A 1999-06-11 1999-06-11 Biomateriau a base d'un derive de dextrane insolubilise et d'un facteur de croissance, son procede de preparation et ses applications Expired - Fee Related FR2794649B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR9907401A FR2794649B1 (fr) 1999-06-11 1999-06-11 Biomateriau a base d'un derive de dextrane insolubilise et d'un facteur de croissance, son procede de preparation et ses applications
PCT/FR2000/001603 WO2000076562A1 (fr) 1999-06-11 2000-06-09 Biomateriau a base d'un derive de dextrane insolubilise et d'un facteur de croissance
CA002376898A CA2376898A1 (fr) 1999-06-11 2000-06-09 Biomateriau a base d'un derive de dextrane insolubilise et d'un facteur de croissance
JP2001502893A JP2003501217A (ja) 1999-06-11 2000-06-09 不溶化デキストラン誘導体および増殖因子に基づく生体材料
EP00940481A EP1189644A1 (fr) 1999-06-11 2000-06-09 Biomateriau a base d'un derive de dextrance insolubilise et d'un facteur de croissance
US10/016,706 US6946443B2 (en) 1999-06-11 2001-12-11 Biomaterial based on an insolubilized dextran derivative and a growth factor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9907401A FR2794649B1 (fr) 1999-06-11 1999-06-11 Biomateriau a base d'un derive de dextrane insolubilise et d'un facteur de croissance, son procede de preparation et ses applications

Publications (2)

Publication Number Publication Date
FR2794649A1 FR2794649A1 (fr) 2000-12-15
FR2794649B1 true FR2794649B1 (fr) 2003-04-11

Family

ID=9546668

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9907401A Expired - Fee Related FR2794649B1 (fr) 1999-06-11 1999-06-11 Biomateriau a base d'un derive de dextrane insolubilise et d'un facteur de croissance, son procede de preparation et ses applications

Country Status (6)

Country Link
US (1) US6946443B2 (fr)
EP (1) EP1189644A1 (fr)
JP (1) JP2003501217A (fr)
CA (1) CA2376898A1 (fr)
FR (1) FR2794649B1 (fr)
WO (1) WO2000076562A1 (fr)

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* Cited by examiner, † Cited by third party
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JP4266637B2 (ja) * 2001-02-05 2009-05-20 ミリポア・コーポレイション 微生物の検出
US20080086792A1 (en) 2006-10-13 2008-04-17 Thomas Charles Kuracina Method and apparatus for diverting sweat, liquid, moisture or the like from an eye
DE60323943D1 (de) * 2002-02-21 2008-11-20 Encelle Inc Immobilisierte bioaktive hydrogel matrizen für oberflächenbeschichtungen
US20110097385A1 (en) * 2003-03-04 2011-04-28 Ttdc Bio L.P. Delivery System for Drug and Cell Therapy
NZ581804A (en) * 2003-10-22 2011-10-28 Encelle Inc Bioactive hydrogel compositions for regenerating connective tissue
FR2891149B1 (fr) * 2005-09-26 2007-11-30 Biodex Sarl Composition pharmaceutique a action cicatrisante comprenant un derive de dextrane soluble et un facteur de croissance derive des plaquettes.
WO2008090583A1 (fr) * 2007-01-22 2008-07-31 Universita' Degli Studi Di Siena Dérivés phosphatés de polysaccharides et leurs utilisations
EP1964583A1 (fr) 2007-02-09 2008-09-03 Royal College of Surgeons in Ireland Processus de production d'une base composite de collagène/hydroxyapatite
US8133553B2 (en) 2007-06-18 2012-03-13 Zimmer, Inc. Process for forming a ceramic layer
US8309521B2 (en) 2007-06-19 2012-11-13 Zimmer, Inc. Spacer with a coating thereon for use with an implant device
FR2919188B1 (fr) * 2007-07-27 2010-02-26 Proteins & Peptides Man Complexes entre un polymere amphiphile et une proteine osteogenique appartenant a la famille des bmps
US8608049B2 (en) 2007-10-10 2013-12-17 Zimmer, Inc. Method for bonding a tantalum structure to a cobalt-alloy substrate
US20090291113A1 (en) * 2008-04-14 2009-11-26 Adocia Osteogenic composition comprising a growth factor, a soluble cation salt and organic support
FR2937863B1 (fr) * 2008-11-06 2012-05-18 Adocia Composition osteogenique comprenant un complexe facteur de croissance polysaccharide anionique, un sel soluble de cation et un gel
CA2720203A1 (fr) * 2008-04-14 2009-10-22 Adocia Composition osteogenique comprenant un complexe facteur de croissance/polymere amphiphile un sel soluble de cation et un support organique
FR2933306B1 (fr) * 2008-07-07 2010-09-10 Adocia Composition osteogenique comprenant un complexe facteur de croissance polysaccharide anionique, un sel soluble de cation et une matrice organique
FR2948573B1 (fr) * 2009-07-31 2011-11-18 Adocia Nouvelle forme d'administration de complexes de proteines osteogeniques
US8529933B2 (en) 2009-07-27 2013-09-10 Warsaw Orthopedic, Inc. Biphasic calcium phosphate cement for drug delivery
US9700650B2 (en) 2009-11-09 2017-07-11 Spotlight Technology Partners Llc Polysaccharide based hydrogels
CN107033368A (zh) 2009-11-09 2017-08-11 聚光灯技术合伙有限责任公司 碎裂水凝胶
FR2966248B1 (fr) * 2010-10-18 2020-05-01 Centre National De La Recherche Scientifique (Cnrs) Procede de fonctionnalisation de surfaces pour la detection d'analytes
WO2013096650A2 (fr) 2011-12-23 2013-06-27 Pioneer Surgical Technology Matrice continue dans laquelle des particules ostéoconductrices sont dispersées, procédé de formation de cette matrice et procédé de régénération osseuse à l'aide de cette matrice
ES2959451T3 (es) 2013-09-11 2024-02-26 Eagle Biologics Inc Formulaciones proteicas líquidas que contienen organofosfatos
WO2015111062A1 (fr) * 2014-01-27 2015-07-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd Nanoencapsulation de composés hydrophiles actifs
KR102497368B1 (ko) * 2014-10-01 2023-02-10 이글 바이올로직스 인코포레이티드 점도-저하제를 함유하는 폴리삭카라이드 및 핵산 제형
EP3097922A1 (fr) * 2015-05-28 2016-11-30 Denis Barritault Composition pour le traitement des lesions tissulaires
CN108732296B (zh) * 2017-04-14 2020-12-04 常州药物研究所有限公司 交联葡聚糖微球的交联度检测方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5100668A (en) * 1988-06-14 1992-03-31 Massachusetts Institute Of Technology Controlled release systems containing heparin and growth factors
FR2644066B1 (fr) * 1989-03-09 1994-05-13 Therapeutiques Substitutives Compositions stabilisees comprenant des fgfs, leur procede d'obtention et leurs applications therapeutiques, chirurgicales et cosmetologiques
JPH05238930A (ja) * 1992-02-28 1993-09-17 Eisai Co Ltd 持続性薬剤
EP0634481B1 (fr) 1993-07-14 2000-03-22 The Procter & Gamble Company Compositions détergentes
FR2718024B1 (fr) * 1994-03-30 1996-06-21 Paris Val Marne Universite Médicament et composition pharmaceutique pour le traitement de l'inflammation.
FR2722982A1 (fr) 1994-07-26 1996-02-02 Bernard Rousseau Semelle d'appui pour platre de marche
JP4247846B2 (ja) * 1997-07-03 2009-04-02 デュピュイ・スパイン・インコーポレーテッド 架橋ポリサッカリド薬物キャリア
FR2772382B1 (fr) * 1997-12-11 2000-03-03 Solutions Derives de dextrane, leur procede de preparation et leurs applications comme medicaments a action biologique specifique

Also Published As

Publication number Publication date
CA2376898A1 (fr) 2000-12-21
FR2794649A1 (fr) 2000-12-15
WO2000076562A9 (fr) 2002-01-24
US6946443B2 (en) 2005-09-20
JP2003501217A (ja) 2003-01-14
WO2000076562A1 (fr) 2000-12-21
US20020169120A1 (en) 2002-11-14
EP1189644A1 (fr) 2002-03-27

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Legal Events

Date Code Title Description
CL Concession to grant licences
CA Change of address
TP Transmission of property
CA Change of address
AU Other action affecting the ownership or exploitation of an industrial property right
ST Notification of lapse

Effective date: 20080229