FR2712888B1 - Utilisation de alpha-D-alkylglucopyranosides et esters de ceux-ci pour la préparation de prodrogues capables de traverser la barrière hématoencéphalique, prodrogues obtenues et précurseurs de celles-ci. - Google Patents

Utilisation de alpha-D-alkylglucopyranosides et esters de ceux-ci pour la préparation de prodrogues capables de traverser la barrière hématoencéphalique, prodrogues obtenues et précurseurs de celles-ci.

Info

Publication number
FR2712888B1
FR2712888B1 FR9313994A FR9313994A FR2712888B1 FR 2712888 B1 FR2712888 B1 FR 2712888B1 FR 9313994 A FR9313994 A FR 9313994A FR 9313994 A FR9313994 A FR 9313994A FR 2712888 B1 FR2712888 B1 FR 2712888B1
Authority
FR
France
Prior art keywords
prodrugs
alkylglucopyranosides
precursors
crossing
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9313994A
Other languages
English (en)
Other versions
FR2712888A1 (fr
Inventor
Jean Franck Pierre Louis Fabre
Francois Marie Bernard Paul
Pierre Frederic Emmanue Monsan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioeurope
Original Assignee
Bioeurope
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioeurope filed Critical Bioeurope
Priority to FR9313994A priority Critical patent/FR2712888B1/fr
Priority to PCT/FR1994/001363 priority patent/WO1995014705A1/fr
Publication of FR2712888A1 publication Critical patent/FR2712888A1/fr
Application granted granted Critical
Publication of FR2712888B1 publication Critical patent/FR2712888B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/549Sugars, nucleosides, nucleotides or nucleic acids
FR9313994A 1993-11-23 1993-11-23 Utilisation de alpha-D-alkylglucopyranosides et esters de ceux-ci pour la préparation de prodrogues capables de traverser la barrière hématoencéphalique, prodrogues obtenues et précurseurs de celles-ci. Expired - Fee Related FR2712888B1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR9313994A FR2712888B1 (fr) 1993-11-23 1993-11-23 Utilisation de alpha-D-alkylglucopyranosides et esters de ceux-ci pour la préparation de prodrogues capables de traverser la barrière hématoencéphalique, prodrogues obtenues et précurseurs de celles-ci.
PCT/FR1994/001363 WO1995014705A1 (fr) 1993-11-23 1994-11-22 UTILISATION DE α-D-ALKYLGLUCOPYRANOSIDES ET ESTERS DE CEUX-CI POUR LA PREPARATION DE PRODROGUES CAPABLES DE TRAVERSER LA BARRIERE HEMATO-ENCEPHALIQUE, PRODROGUES ET PRECURSEURS DE CELLES-CI

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9313994A FR2712888B1 (fr) 1993-11-23 1993-11-23 Utilisation de alpha-D-alkylglucopyranosides et esters de ceux-ci pour la préparation de prodrogues capables de traverser la barrière hématoencéphalique, prodrogues obtenues et précurseurs de celles-ci.

Publications (2)

Publication Number Publication Date
FR2712888A1 FR2712888A1 (fr) 1995-06-02
FR2712888B1 true FR2712888B1 (fr) 1996-02-09

Family

ID=9453140

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9313994A Expired - Fee Related FR2712888B1 (fr) 1993-11-23 1993-11-23 Utilisation de alpha-D-alkylglucopyranosides et esters de ceux-ci pour la préparation de prodrogues capables de traverser la barrière hématoencéphalique, prodrogues obtenues et précurseurs de celles-ci.

Country Status (2)

Country Link
FR (1) FR2712888B1 (fr)
WO (1) WO1995014705A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19524515A1 (de) * 1995-07-05 1997-01-09 Deutsches Krebsforsch Saccharid-Konjugate
FR2768630B1 (fr) * 1997-09-22 2000-08-04 Ulice Sa Utilisation d'alkyl monoglucosides en tant que vecteurs moleculaires
DE69808017T2 (de) 1997-10-31 2003-04-30 Hoffmann La Roche D-Prolinderivate
JP5328183B2 (ja) * 2008-03-17 2013-10-30 国立大学法人 長崎大学 グルコシドエステル誘導体の製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4034083A (en) * 1975-11-03 1977-07-05 The Procter & Gamble Company Compositions for inhibiting absorption of cholesterol
US4939174A (en) * 1988-02-26 1990-07-03 Shashoua Victor E Appetite suppression with dopamine-fatty acid conjugates
EP0413307A1 (fr) * 1989-08-15 1991-02-20 Lion Corporation Procédé de fabrication de saccharides mono-estérifiés par des acides gras
FR2676058B1 (fr) * 1991-04-30 1994-02-25 Hoechst Lab Prodrogues glycosylees, leur procede de preparation et leur utilisation dans le traitement des cancers.
JPH0543428A (ja) * 1991-08-13 1993-02-23 Lion Corp 化粧料

Also Published As

Publication number Publication date
WO1995014705A1 (fr) 1995-06-01
FR2712888A1 (fr) 1995-06-02

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20090731