FR2697163B1 - PROCESS FOR THE MANUFACTURE OF BOTULINUM TOXIN TYPE A, CRYSTALLINE, AS A MEDICAMENT. - Google Patents

PROCESS FOR THE MANUFACTURE OF BOTULINUM TOXIN TYPE A, CRYSTALLINE, AS A MEDICAMENT.

Info

Publication number
FR2697163B1
FR2697163B1 FR9312505A FR9312505A FR2697163B1 FR 2697163 B1 FR2697163 B1 FR 2697163B1 FR 9312505 A FR9312505 A FR 9312505A FR 9312505 A FR9312505 A FR 9312505A FR 2697163 B1 FR2697163 B1 FR 2697163B1
Authority
FR
France
Prior art keywords
medicament
crystalline
manufacture
botulinum toxin
toxin type
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9312505A
Other languages
French (fr)
Other versions
FR2697163A1 (en
Inventor
Sakaguchi Genji
Shimizu Tomoko
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chiba Prefectural Government
Original Assignee
Chiba Prefectural Government
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiba Prefectural Government filed Critical Chiba Prefectural Government
Publication of FR2697163A1 publication Critical patent/FR2697163A1/en
Application granted granted Critical
Publication of FR2697163B1 publication Critical patent/FR2697163B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FR9312505A 1992-10-28 1993-10-20 PROCESS FOR THE MANUFACTURE OF BOTULINUM TOXIN TYPE A, CRYSTALLINE, AS A MEDICAMENT. Expired - Fee Related FR2697163B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4311158A JPH06192296A (en) 1992-10-28 1992-10-28 Production of crystal a type botulinus toxin as medicine for therapy

Publications (2)

Publication Number Publication Date
FR2697163A1 FR2697163A1 (en) 1994-04-29
FR2697163B1 true FR2697163B1 (en) 1995-06-23

Family

ID=18013801

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9312505A Expired - Fee Related FR2697163B1 (en) 1992-10-28 1993-10-20 PROCESS FOR THE MANUFACTURE OF BOTULINUM TOXIN TYPE A, CRYSTALLINE, AS A MEDICAMENT.

Country Status (6)

Country Link
JP (1) JPH06192296A (en)
DE (1) DE4335366A1 (en)
DK (1) DK112793A (en)
FR (1) FR2697163B1 (en)
GB (1) GB2272697A (en)
SE (1) SE9303323L (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5919665A (en) 1989-10-31 1999-07-06 Ophidian Pharmaceuticals, Inc. Vaccine for clostridium botulinum neurotoxin
GB9120306D0 (en) 1991-09-24 1991-11-06 Graham Herbert K Method and compositions for the treatment of cerebral palsy
US8187612B2 (en) 1993-12-28 2012-05-29 Allergan, Inc. Use of the neurotoxic component of a botulinum toxin for treating a spastic muscle
US8557256B2 (en) 1993-12-28 2013-10-15 Allergan, Inc. Treatment for cervical dystonia with the neurotoxic component of a botulinum toxin
US6974578B1 (en) 1993-12-28 2005-12-13 Allergan, Inc. Method for treating secretions and glands using botulinum toxin
HUT78048A (en) * 1994-10-24 1999-07-28 Ophidian Pharmaceuticals, Inc. Vaccine and antitoxin for treatment and prevention of c. difficile disease
JP2003009897A (en) 2001-07-03 2003-01-14 Keiji Oguma Method for separating and purifying botulinus toxin
CN102614264A (en) * 2012-05-02 2012-08-01 马守云 Medicine for treating eyelid spasm
RU2535115C1 (en) 2013-05-15 2014-12-10 Бости Трейдинг Лтд Pharmaceutical formulation containing botulinum neurotoxin
KR101775682B1 (en) 2015-11-30 2017-09-06 주식회사 대웅 Methods for Preparing Botulinum Toxin

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR940005589B1 (en) * 1986-04-02 1994-06-21 다이닛뽄세이야꾸 가부시끼가이샤 Method for removal of nucleic acids and/or endotoxin
US5053005A (en) * 1989-04-21 1991-10-01 Gary E. Borodic Chemomodulation of curvature of the juvenile spine

Also Published As

Publication number Publication date
SE9303323D0 (en) 1993-10-11
JPH06192296A (en) 1994-07-12
GB2272697A (en) 1994-05-25
GB9321794D0 (en) 1993-12-15
FR2697163A1 (en) 1994-04-29
DE4335366A1 (en) 1994-05-05
DK112793A (en) 1994-04-29
SE9303323L (en) 1994-04-29
DK112793D0 (en) 1993-10-08

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Legal Events

Date Code Title Description
ST Notification of lapse