FR2684671B1 - NEW QUINOLEIN DERIVATIVES, THEIR PREPARATION AND INTERMEDIATE PROCESSES AND THEIR APPLICATION AS MEDICAMENTS. - Google Patents
NEW QUINOLEIN DERIVATIVES, THEIR PREPARATION AND INTERMEDIATE PROCESSES AND THEIR APPLICATION AS MEDICAMENTS.Info
- Publication number
- FR2684671B1 FR2684671B1 FR9114282A FR9114282A FR2684671B1 FR 2684671 B1 FR2684671 B1 FR 2684671B1 FR 9114282 A FR9114282 A FR 9114282A FR 9114282 A FR9114282 A FR 9114282A FR 2684671 B1 FR2684671 B1 FR 2684671B1
- Authority
- FR
- France
- Prior art keywords
- medicaments
- preparation
- new
- application
- intermediate processes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/36—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/28—Cinnolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (25)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9114282A FR2684671B1 (en) | 1991-11-20 | 1991-11-20 | NEW QUINOLEIN DERIVATIVES, THEIR PREPARATION AND INTERMEDIATE PROCESSES AND THEIR APPLICATION AS MEDICAMENTS. |
IL10055591A IL100555A (en) | 1991-02-07 | 1991-12-30 | N-substituted quinoline derivatives their preparation their use for the preparation of medicaments and the pharmaceutical compositions containing them |
MA22697A MA22410A1 (en) | 1991-02-07 | 1992-02-04 | NOVEL N-SUBSTITUTED QUINOLEIN DERIVATIVES, THEIR PREPARATION PROCESS, THE NEW INTERMEDIATES, THEIR APPLICATION AND THE COMPOSITIONS CONTAINING THEM |
JP04759492A JP3599350B2 (en) | 1991-02-07 | 1992-02-04 | Novel N-substituted quinoline derivatives, their preparation, their use as medicaments and pharmaceutical compositions containing them |
PT92400294T PT498721E (en) | 1991-02-07 | 1992-02-05 | N-SUBSTITUTED QUINOLEIN DERIVATIVES, ITS PREPARATION PROCESS, ITS APPLICATION TO TITLE OF PHARMACEUTICAL MEDICINAL PRODUCTS AND COMPOSITIONS THAT CONTAIN THEM |
DE69230449T DE69230449T2 (en) | 1991-02-07 | 1992-02-05 | N-substituted quinoline derivatives, processes for their preparation, their use as medicaments and pharmaceutical compositions containing them |
ES92400294T ES2141098T3 (en) | 1991-02-07 | 1992-02-05 | N-SUBSTITUTED DERIVATIVES OF QUINOLINE, ITS PREPARATION PROCEDURE, ITS APPLICATION AS MEDICINES, AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM. |
DK92400294T DK0498721T3 (en) | 1991-02-07 | 1992-02-05 | New N-Substituted Quinoline Compounds, Processes for their Preparation, Intermediates thereof, Their Use as |
EP92400294A EP0498721B1 (en) | 1991-02-07 | 1992-02-05 | N-substituted quinoline derivatives, process for their preparation, their use as pharmaceuticals and pharmaceutical compositions containing them |
AT92400294T ATE187964T1 (en) | 1991-02-07 | 1992-02-05 | N-SUBSTITUTED QUINOLINE DERIVATIVES, METHOD FOR PRODUCTION, THEIR USE AS MEDICINAL PRODUCTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME |
HU9200367A HUT64524A (en) | 1991-02-07 | 1992-02-06 | Process for the production of novel n-substituted kinoline derivatives and of medical preparations containing them |
IE039592A IE920395A1 (en) | 1991-02-07 | 1992-02-06 | New n-substituted quinoline derivatives, their preparation¹process, the new intermediates obtained, their use as¹medicaments and the pharmaceutical compositions containing¹them |
KR1019920001715A KR100334208B1 (en) | 1991-02-07 | 1992-02-06 | Novel N-substituted quinoline derivatives, methods for their preparation, new intermediates, their use as pharmaceuticals and pharmaceutical compositions containing them |
SU5010859A RU2125047C1 (en) | 1991-02-07 | 1992-02-06 | N-derivatives of quinoline or their additive salts with inorganic or organic acids or with inorganic and organic bases, methods of their synthesis and pharmaceutical composition based on them |
FI920504A FI103574B1 (en) | 1991-02-07 | 1992-02-06 | Process for the preparation of therapeutically useful N-substituted quinoline and quinoline derivatives |
CS1992357A CZ291217B6 (en) | 1991-02-07 | 1992-02-07 | Quinoline N-substituted derivatives, process of their preparation, the derivatives as medicaments, pharmaceutical compositions containing such derivatives and use of these derivatives for preparing a medicament |
CN92100765A CN1064076A (en) | 1991-02-07 | 1992-02-07 | Quinoline, its method for making, intermediate, purposes and composition that N-replaces |
PL92293414A PL169672B1 (en) | 1991-02-07 | 1992-02-07 | Method of obtaining novel n-substituted derivatives of quinoline |
BR929200432A BR9200432A (en) | 1991-02-07 | 1992-02-07 | PROCESS TO PREPARE PRODUCTS AND PROCESS TO PREPARE PHARMACEUTICAL COMPOSITIONS |
OA60146A OA09528A (en) | 1991-02-07 | 1992-02-07 | New N-substituted quinoline derivatives their preparation process the new intermediates obtained their application as medicaments and the pharmaceutical compositions containing them |
NZ241546A NZ241546A (en) | 1991-02-07 | 1992-02-07 | N-substituted quinoline and cinnoline derivatives, preparation and pharmaceutical compositions thereof |
CA002060843A CA2060843A1 (en) | 1991-02-07 | 1992-02-07 | N-substituted derivatives of quinoleine, process for their preparation, new intermediates obtaines, their application as drugs and pharmaceutical compositions containing them |
TW081101181A TW214554B (en) | 1991-02-07 | 1992-02-18 | |
US08/964,182 US5985894A (en) | 1991-02-07 | 1997-11-04 | N-substituted quinolines |
GR20000400410T GR3032711T3 (en) | 1991-02-07 | 2000-02-18 | N-substituted quinoline derivatives, process for their preparation, intermediates obtained, their use as pharmaceuticals and pharmaceutical compositions containing them. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9114282A FR2684671B1 (en) | 1991-11-20 | 1991-11-20 | NEW QUINOLEIN DERIVATIVES, THEIR PREPARATION AND INTERMEDIATE PROCESSES AND THEIR APPLICATION AS MEDICAMENTS. |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2684671A1 FR2684671A1 (en) | 1993-06-11 |
FR2684671B1 true FR2684671B1 (en) | 1995-05-19 |
Family
ID=9419131
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR9114282A Expired - Fee Related FR2684671B1 (en) | 1991-02-07 | 1991-11-20 | NEW QUINOLEIN DERIVATIVES, THEIR PREPARATION AND INTERMEDIATE PROCESSES AND THEIR APPLICATION AS MEDICAMENTS. |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2684671B1 (en) |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1419789A (en) * | 1972-08-02 | 1975-12-31 | Pfizer | 2-trifluoromethyl-4-quinolinols |
GB1432649A (en) * | 1973-09-07 | 1976-04-22 | Ici Ltd | |
GB1472767A (en) * | 1974-11-07 | 1977-05-04 | Ici Ltd | Process for the preparation of cinnoline derivatives |
FR2377400A2 (en) * | 1977-01-18 | 1978-08-11 | Roussel Uclaf | Analgesic hydroxy:quinoline carboxamide cpds. - esp. N-(2-thiazolyl)-carboxamide cpds. with 8-tri:fluoro:methyl substit. |
NZ193167A (en) * | 1979-03-27 | 1984-08-24 | Boots Co Plc | Quinoline derivatives and pharmaceutical compositions |
JPS58219166A (en) * | 1982-06-14 | 1983-12-20 | Nippon Shinyaku Co Ltd | 4-quinolone derivative |
JPS6461461A (en) * | 1987-09-01 | 1989-03-08 | Otsuka Pharma Co Ltd | Benzohetero ring derivative |
DE68917024D1 (en) * | 1988-05-24 | 1994-09-01 | Kirin Brewery | 4 (1H) quinolone derivatives. |
-
1991
- 1991-11-20 FR FR9114282A patent/FR2684671B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
FR2684671A1 (en) | 1993-06-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
CA | Change of address | ||
CD | Change of name or company name | ||
TP | Transmission of property | ||
ST | Notification of lapse |