FR2678267B1 - Arylalkylamines, procede pour leur preparation et compositions pharmaceutiques les contenant. - Google Patents

Arylalkylamines, procede pour leur preparation et compositions pharmaceutiques les contenant.

Info

Publication number
FR2678267B1
FR2678267B1 FR9107824A FR9107824A FR2678267B1 FR 2678267 B1 FR2678267 B1 FR 2678267B1 FR 9107824 A FR9107824 A FR 9107824A FR 9107824 A FR9107824 A FR 9107824A FR 2678267 B1 FR2678267 B1 FR 2678267B1
Authority
FR
France
Prior art keywords
arylalkylamines
preparation
pharmaceutical compositions
compositions containing
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9107824A
Other languages
English (en)
Other versions
FR2678267A1 (fr
Inventor
Xavier Emonds-Alt
Pierre Goulaouic
Vincenzo Proietto
Broeck Didier Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elf Sanofi SA
Original Assignee
Elf Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elf Sanofi SA filed Critical Elf Sanofi SA
Priority to FR9107824A priority Critical patent/FR2678267B1/fr
Priority to IL9932091A priority patent/IL99320A/en
Priority to IE308291A priority patent/IE913082A1/en
Priority to BR919103802A priority patent/BR9103802A/pt
Priority to PT98849A priority patent/PT98849B/pt
Priority to AU83542/91A priority patent/AU657272B2/en
Priority to CA002050639A priority patent/CA2050639C/fr
Priority to UA5001435A priority patent/UA27224C2/uk
Priority to NZ239661A priority patent/NZ239661A/en
Priority to HU9102863A priority patent/HU222351B1/hu
Priority to FI914174A priority patent/FI98457C/fi
Priority to SU5001435/04A priority patent/RU2070196C1/ru
Priority to PL91291618A priority patent/PL167994B1/pl
Priority to NO913469A priority patent/NO177226C/no
Priority to US07/755,454 priority patent/US5236921A/en
Priority to ES91402382T priority patent/ES2127722T3/es
Priority to SG1996003908A priority patent/SG47703A1/en
Priority to JP3254730A priority patent/JP2620435B2/ja
Priority to AT91402382T priority patent/ATE174332T1/de
Priority to CS912724A priority patent/CZ285994B6/cs
Priority to MYPI91001612A priority patent/MY142065A/en
Priority to EP91402382A priority patent/EP0474561B1/fr
Priority to KR1019910015523A priority patent/KR100194823B1/ko
Priority to DK91402382T priority patent/DK0474561T3/da
Priority to DE69130597T priority patent/DE69130597T2/de
Priority to MX9102003A priority patent/MX9102003A/es
Publication of FR2678267A1 publication Critical patent/FR2678267A1/fr
Priority to LVP-93-139A priority patent/LV10606B/en
Priority to US08/105,677 priority patent/US5350852A/en
Application granted granted Critical
Publication of FR2678267B1 publication Critical patent/FR2678267B1/fr
Priority to HU95P/P00521P priority patent/HU211893A9/hu
Priority to BR1100257A priority patent/BR1100257A/pt
Priority to HK98104394A priority patent/HK1005290A1/xx
Priority to GR990400518T priority patent/GR3029435T3/el
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/48—Oxygen atoms attached in position 4 having an acyclic carbon atom attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR9107824A 1990-09-05 1991-06-25 Arylalkylamines, procede pour leur preparation et compositions pharmaceutiques les contenant. Expired - Lifetime FR2678267B1 (fr)

Priority Applications (32)

Application Number Priority Date Filing Date Title
FR9107824A FR2678267B1 (fr) 1991-06-25 1991-06-25 Arylalkylamines, procede pour leur preparation et compositions pharmaceutiques les contenant.
IL9932091A IL99320A (en) 1990-09-05 1991-08-27 Arylalkylamines, their preparation and pharmaceutical preparations containing them
IE308291A IE913082A1 (en) 1990-09-05 1991-09-02 Arylalkylamines, process for preparing them and¹pharmaceutical compositions containing them
PT98849A PT98849B (pt) 1990-09-05 1991-09-03 Processo para a obtencao de arilalquilaminas substituidas, nomeadamente, com piperidinilo substituido
BR919103802A BR9103802A (pt) 1990-09-05 1991-09-03 Composto,processo para a preparacao do mesmo e composicao farmaceutico
AU83542/91A AU657272B2 (en) 1990-09-05 1991-09-03 Arylalkylamines, process for preparing them and pharmaceutical compositions containing them
UA5001435A UA27224C2 (uk) 1990-09-05 1991-09-04 Арилалкіламіни, спосіб їх одержання та фармацевтична композиція
NZ239661A NZ239661A (en) 1990-09-05 1991-09-04 Piperidine and piperazine derivatives and pharmaceutical compositions
HU9102863A HU222351B1 (hu) 1990-09-05 1991-09-04 Aril-alkil-aminok, eljárás ezek előállítására és az ezeket tartalmazó gyógyszerkészítmények
FI914174A FI98457C (fi) 1990-09-05 1991-09-04 Menetelmä piperidyylialkyyliamiinien valmistamiseksi
SU5001435/04A RU2070196C1 (ru) 1990-09-05 1991-09-04 Арилалкиламины и фармацевтическая композиция на их основе
PL91291618A PL167994B1 (pl) 1990-09-05 1991-09-04 Sposób wytwarzania nowych aryloalkiloamin PL PL PL PL PL PL
NO913469A NO177226C (no) 1990-09-05 1991-09-04 Analogifremgangsmåte for fremstilling av terapeutisk aktive arylalkylaminer
CA002050639A CA2050639C (fr) 1990-09-05 1991-09-04 Arylalkylamines, mode de preparation et compositions pharmaceutiques quien contiennent
JP3254730A JP2620435B2 (ja) 1990-09-05 1991-09-05 アリールアルキルアミン類、その製造方法およびこれを含有する薬剤組成物
SG1996003908A SG47703A1 (en) 1990-09-05 1991-09-05 Arylalkylamines process for preparing them and pharmaceutical compositions containing them
US07/755,454 US5236921A (en) 1990-09-05 1991-09-05 Arylalkylamines, process for preparing them and pharmaceutical compositions containing them
AT91402382T ATE174332T1 (de) 1990-09-05 1991-09-05 Arylalkylamine, verfahren zur herstellung und diese enthaltende arzneimittel
CS912724A CZ285994B6 (cs) 1990-09-05 1991-09-05 Arylalkylaminy, způsob jejich přípravy a farmaceutické kompozice tyto arylalkylaminy obsahující
MYPI91001612A MY142065A (en) 1990-09-05 1991-09-05 Arylalkylamines, process for preparing them and pharmaceutical compositions containing them
EP91402382A EP0474561B1 (fr) 1990-09-05 1991-09-05 Arylalkylamines, procédé pour leur préparation et compositions pharmaceutiques les contenant
KR1019910015523A KR100194823B1 (ko) 1990-09-05 1991-09-05 아릴알킬아민, 이의 제조방법 및 이를 함유하는 약제학적 조성물
DK91402382T DK0474561T3 (da) 1990-09-05 1991-09-05 Arylalkylaminer, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse
DE69130597T DE69130597T2 (de) 1990-09-05 1991-09-05 Arylalkylamine, Verfahren zur Herstellung und diese enthaltende Arzneimittel
ES91402382T ES2127722T3 (es) 1990-09-05 1991-09-05 Aralquilaminas, procedimiento para su preparacion y composiciones farmaceuticas que las contienen.
MX9102003A MX9102003A (es) 1991-06-25 1991-11-11 Aril alquil aminas y procedimiento para su preparacion.
LVP-93-139A LV10606B (en) 1990-09-05 1993-02-25 Arylalkylamines, process for preparing them and pharmaceutical compositions containing them
US08/105,677 US5350852A (en) 1990-09-05 1993-08-13 Arylalkylamines, process for preparing them and pharmaceutical compositions containing them
HU95P/P00521P HU211893A9 (en) 1990-09-05 1995-06-28 Arylalkylamines, process for preparing them and pharmaceutical compositions containing them
BR1100257A BR1100257A (pt) 1991-06-25 1997-04-10 Composto, processo para a preparação do mesmo e composição farmacêutica
HK98104394A HK1005290A1 (en) 1990-09-05 1998-05-21 Arylalkylamines process for their preparation and pharmaceutical compositions containing them
GR990400518T GR3029435T3 (en) 1990-09-05 1999-02-17 Arylalkylamines, process for their preparation and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9107824A FR2678267B1 (fr) 1991-06-25 1991-06-25 Arylalkylamines, procede pour leur preparation et compositions pharmaceutiques les contenant.

Publications (2)

Publication Number Publication Date
FR2678267A1 FR2678267A1 (fr) 1992-12-31
FR2678267B1 true FR2678267B1 (fr) 1994-02-04

Family

ID=9414264

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9107824A Expired - Lifetime FR2678267B1 (fr) 1990-09-05 1991-06-25 Arylalkylamines, procede pour leur preparation et compositions pharmaceutiques les contenant.

Country Status (3)

Country Link
BR (1) BR1100257A (fr)
FR (1) FR2678267B1 (fr)
MX (1) MX9102003A (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2700472B1 (fr) 1993-01-19 1995-02-17 Rhone Poulenc Rorer Sa Association synergisante ayant un effet antagoniste des récepteurs NK1 et NK2.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL254248A (fr) * 1959-07-29
US4791121A (en) * 1987-11-02 1988-12-13 The Boc Group, Inc. 4-phenyl-4-(N-(phenyl)amido) piperidine derivatives and pharmaceutical compositions and method employing such compounds
FI97540C (fi) * 1989-11-06 1997-01-10 Sanofi Sa Menetelmä terapeuttisesti käyttökelpoisten, aromaattisesti substituoitujen piperidiini- ja piperatsiinijohdannaisten valmistamiseksi

Also Published As

Publication number Publication date
MX9102003A (es) 1992-12-01
BR1100257A (pt) 1999-11-23
FR2678267A1 (fr) 1992-12-31

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