FR2627492B1 - NOVEL AMINO-5 (PRIME) -DIDEOXY-2 (PRIME) -5 (PRIME) -URIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS - Google Patents

NOVEL AMINO-5 (PRIME) -DIDEOXY-2 (PRIME) -5 (PRIME) -URIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS

Info

Publication number
FR2627492B1
FR2627492B1 FR8802255A FR8802255A FR2627492B1 FR 2627492 B1 FR2627492 B1 FR 2627492B1 FR 8802255 A FR8802255 A FR 8802255A FR 8802255 A FR8802255 A FR 8802255A FR 2627492 B1 FR2627492 B1 FR 2627492B1
Authority
FR
France
Prior art keywords
prime
dideoxy
compounds
preparation
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR8802255A
Other languages
French (fr)
Other versions
FR2627492A1 (en
Inventor
Jean-Luc Moriniere
Michelle Faulques
Claude Rousseau
Bernard Danree
Claude Marquer
Patrick Saur
Jean Lemoine
Jean-Yves Lacolle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut de Recherches Chimiques et Biologiques Appliquees SARL IRCEBA
Original Assignee
Institut de Recherches Chimiques et Biologiques Appliquees SARL IRCEBA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR8802255A priority Critical patent/FR2627492B1/en
Application filed by Institut de Recherches Chimiques et Biologiques Appliquees SARL IRCEBA filed Critical Institut de Recherches Chimiques et Biologiques Appliquees SARL IRCEBA
Priority to EP89903177A priority patent/EP0448550B1/en
Priority to AT89903177T priority patent/ATE109789T1/en
Priority to US07/566,344 priority patent/US5212161A/en
Priority to JP1502971A priority patent/JPH03504492A/en
Priority to DE68917479T priority patent/DE68917479D1/en
Priority to PCT/FR1989/000072 priority patent/WO1989008115A1/en
Priority to AU32137/89A priority patent/AU631119B2/en
Publication of FR2627492A1 publication Critical patent/FR2627492A1/en
Application granted granted Critical
Publication of FR2627492B1 publication Critical patent/FR2627492B1/en
Priority to DK200290A priority patent/DK200290D0/en
Priority to FI904171A priority patent/FI92324C/en
Priority to NO903704A priority patent/NO173507C/en
Priority to OA59844A priority patent/OA09306A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR8802255A 1988-02-24 1988-02-24 NOVEL AMINO-5 (PRIME) -DIDEOXY-2 (PRIME) -5 (PRIME) -URIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS Expired - Lifetime FR2627492B1 (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
FR8802255A FR2627492B1 (en) 1988-02-24 1988-02-24 NOVEL AMINO-5 (PRIME) -DIDEOXY-2 (PRIME) -5 (PRIME) -URIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS
AU32137/89A AU631119B2 (en) 1988-02-24 1989-02-23 New derivatives of deoxy-2'-uridine substituted in the 5,3' or 5' position by acylated alpha-amino groups, process for obtaining them and drugs containing them
US07/566,344 US5212161A (en) 1988-02-24 1989-02-23 Derivatives of 2'-deoxyuridine substituted in the 5-,3'-or 5'-position by α-aminacyl groups, process for their preparation and drugs in which they are present
JP1502971A JPH03504492A (en) 1988-02-24 1989-02-23 New derivatives of 2'-deoxyuridine substituted in the 5-, 3'-, or 5'-position by an α-aminoacyl group and methods for their production and drugs in which they exist.
DE68917479T DE68917479D1 (en) 1988-02-24 1989-02-23 DERIVATIVES OF DEOXY-2'-URIDINE SUBSTITUTED IN THE 5, 3 'OR 5' POSITION BY ACYLATED ALPHA-AMINO GROUPS, METHOD FOR THE PRODUCTION AND MEDICINAL PRODUCTS THEREOF.
PCT/FR1989/000072 WO1989008115A1 (en) 1988-02-24 1989-02-23 NEW DERIVATIVES OF DEOXY-2'-URIDINE SUBSTITUTED IN THE 5, 3' OR 5' POSITION BY ACYLATED alpha-AMINO GROUPS, PROCESS FOR OBTAINING THEM AND DRUGS CONTAINING THEM
EP89903177A EP0448550B1 (en) 1988-02-24 1989-02-23 New derivatives of deoxy-2'-uridine substituted in the 5, 3' or 5' position by acylated alpha-amino groups, process for obtaining them and drugs containing them
AT89903177T ATE109789T1 (en) 1988-02-24 1989-02-23 DERIVATIVES OF DEOXY-2'-URIDINE SUBSTITUTED IN THE 5, 3' OR 5' POSITION BY ACYLATED ALPHA-AMINO GROUPS, PROCESSES FOR THE PREPARATION AND PHARMACEUTICALS THEREOF.
DK200290A DK200290D0 (en) 1988-02-24 1990-08-21 DERIVATIVES OF 2'-DESOXYURIDINE SUBSTITUTED IN 5, 3 'OR 5' POSITION WITH ALFA AMINOACYL GROUPS, PROCEDURES FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM
FI904171A FI92324C (en) 1988-02-24 1990-08-23 Process for the preparation of 2'-deoxyuridine derivatives useful as medicaments
NO903704A NO173507C (en) 1988-02-24 1990-08-23 Analogous Procedure for Preparation of Therapeutically Active Derivatives of Deoxy-2'.uridine
OA59844A OA09306A (en) 1988-02-24 1990-08-24 "New derivatives of deoxy-2'-uridine substituted in position 5, 3 'or 5' by acylated x-amino groups, process for their production and medicaments containing them".

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8802255A FR2627492B1 (en) 1988-02-24 1988-02-24 NOVEL AMINO-5 (PRIME) -DIDEOXY-2 (PRIME) -5 (PRIME) -URIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS

Publications (2)

Publication Number Publication Date
FR2627492A1 FR2627492A1 (en) 1989-08-25
FR2627492B1 true FR2627492B1 (en) 1990-08-10

Family

ID=9363587

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8802255A Expired - Lifetime FR2627492B1 (en) 1988-02-24 1988-02-24 NOVEL AMINO-5 (PRIME) -DIDEOXY-2 (PRIME) -5 (PRIME) -URIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS

Country Status (1)

Country Link
FR (1) FR2627492B1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1246983B (en) * 1990-11-13 1994-12-12 Consiglio Nazionale Ricerche L-2'-DESOXYURIDINE AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4128639A (en) * 1977-12-14 1978-12-05 Research Corporation Nitrosourea analogs of thymidine

Also Published As

Publication number Publication date
FR2627492A1 (en) 1989-08-25

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FR2627492B1 (en) NOVEL AMINO-5 (PRIME) -DIDEOXY-2 (PRIME) -5 (PRIME) -URIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS

Legal Events

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ST Notification of lapse