FR2597869B1 - Nouveaux derives d'ergolene, compositions pharmaceutiques les contenant et procede pour leur preparation - Google Patents

Nouveaux derives d'ergolene, compositions pharmaceutiques les contenant et procede pour leur preparation

Info

Publication number: FR2597869B1
Authority: FR; France
Prior art keywords: novel; preparation; pharmaceutical compositions; compositions containing; ergolene derivatives
Prior art date: 1986-04-25
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

FR878705838A

Other languages

English (en)

Other versions

FR2597869A1 (fr

Inventor

Tibor Keve

Gabor Megyeri

Bela Stefko

Kovacs J Lajos

Anna Kassai-Nee-Zieger

Bela Kiss

Istvan Laszlovszky

Erzsebet Lapis

Eva Palosi

Dora Groo

Laszlo Szporny

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Richter Gedeon Vegyeszeti Gyar Nyrt

Original Assignee

Richter Gedeon Vegyeszeti Gyar RT

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-04-25

Filing date

1987-04-24

Publication date

1991-04-26

1987-04-24 Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT

1987-10-30 Publication of FR2597869A1 publication Critical patent/FR2597869A1/fr

1991-04-26 Application granted granted Critical

1991-04-26 Publication of FR2597869B1 publication Critical patent/FR2597869B1/fr

2007-04-24 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Psychiatry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

FR878705838A 1986-04-25 1987-04-24 Nouveaux derives d'ergolene, compositions pharmaceutiques les contenant et procede pour leur preparation Expired - Fee Related FR2597869B1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU861719A HU196598B (en)	1986-04-25	1986-04-25	Process for producing 1- and/or 8-substituted 2-halogenated ergoline derivatives and pharmaceutics comprising such compounds

Publications (2)

Publication Number	Publication Date
FR2597869A1 FR2597869A1 (fr)	1987-10-30
FR2597869B1 true FR2597869B1 (fr)	1991-04-26

Family

ID=10955843

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FR878705838A Expired - Fee Related FR2597869B1 (fr)	1986-04-25	1987-04-24	Nouveaux derives d'ergolene, compositions pharmaceutiques les contenant et procede pour leur preparation

Country Status (30)

Country	Link
US (1)	US4859682A (fr)
JP (1)	JPS62258379A (fr)
KR (1)	KR920008167B1 (fr)
CN (1)	CN87102944A (fr)
AT (1)	AT391472B (fr)
AU (1)	AU592637B2 (fr)
BE (1)	BE1001159A4 (fr)
CH (1)	CH669791A5 (fr)
CS (1)	CS268534B2 (fr)
DD (1)	DD256133A5 (fr)
DE (1)	DE3713768A1 (fr)
DK (1)	DK208887A (fr)
EG (1)	EG18272A (fr)
ES (1)	ES2007339A6 (fr)
FI (1)	FI871128A (fr)
FR (1)	FR2597869B1 (fr)
GB (1)	GB2189487B (fr)
GR (1)	GR870645B (fr)
HU (1)	HU196598B (fr)
IL (1)	IL82324A0 (fr)
IN (1)	IN165245B (fr)
IT (1)	IT1203976B (fr)
LU (1)	LU86853A1 (fr)
NL (1)	NL8700966A (fr)
NO (1)	NO165800C (fr)
PL (1)	PL152619B1 (fr)
PT (1)	PT84739B (fr)
SE (1)	SE466401B (fr)
SU (1)	SU1500161A3 (fr)
ZA (1)	ZA872931B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU196394B (en) *	1986-06-27	1988-11-28	Richter Gedeon Vegyeszet	Process for preparing 2-halogenated ergoline derivatives
CA2483532A1 (fr) *	2002-04-30	2003-11-13	Biogal Gyogyszergyar Rt.	Nouvelles formes cristallines d'ondansetron, procedes de preparation correspondant, compositions pharmaceutiques contenant ces nouvelles formes et procedes de traitement de la nausee au moyen des ces nouvelles formes
WO2023018480A1 (fr) *	2021-08-09	2023-02-16	University Of Pittsburgh - Of The Commonwealth System Of Higher Education	Composés psychédéliques sélectifs

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE237837C (fr) *
DE1936410A1 (de) *	1969-07-17	1971-02-11	Hoechst Ag	O-Acyl-lysergole und Verfahren zu ihrer Herstellung
AR206772A1 (es) *	1972-07-21	1976-08-23	Lilly Co Eli	Procedimiento para preparar una nueva d-2-halo-6-metil-8-ciano(carboxamido)metil ergolina
US3992385A (en) *	1975-01-20	1976-11-16	Eli Lilly And Company	2,3-Dihydroergolines
CH619709A5 (en) *	1975-03-14	1980-10-15	Siphar Sa	Process for the preparation of carbamates of 2-halogenoergolines and 2-halogenoergolenes
DE2656344A1 (de) *	1975-12-23	1977-07-07	Sandoz Ag	Ergolinderivate, ihre verwendung und herstellung
US4035094A (en) *	1976-03-11	1977-07-12	Trw Inc.	Ball and socket joint
DK75177A (da) *	1976-04-27	1977-10-28	Sandoz Ag	Fremgangsmade til fremstilling af prostaglandiner
US4098790A (en) *	1976-09-15	1978-07-04	Eli Lilly And Company	Ergoline chlorination process
DE3001752A1 (de) *	1980-01-16	1981-07-30	Schering Ag Berlin Und Bergkamen, 1000 Berlin	Verfahren zur herstellung von 8(alpha)-substituierten 6-methylergolinen
DE3151912A1 (de) *	1981-12-23	1983-06-30	Schering Ag, 1000 Berlin Und 4619 Bergkamen	Neue ergolin-aminoderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
DD237837A1 (de) *	1983-11-29	1986-07-30	1086 Berlin,Otto-Nuscke-Str. 2/23,Dd	Verfahren zur herstellung von 2-bromergolinen
DE3403067A1 (de) *	1984-01-30	1985-08-14	Eckart Prof. Dr. 6500 Mainz Eich	Ergolin-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
DE3413657A1 (de) *	1984-04-09	1985-10-17	Schering AG, 1000 Berlin und 4709 Bergkamen	Neue ergoline
HU193781B (en) *	1985-06-21	1987-11-30	Richter Gedeon Vegyeszet	Process for producing 10alpha-methoxy-6-methylergoline derivatives and acid additional salts thereof
US4782152A (en) *	1985-08-16	1988-11-01	Eli Lilly And Company	Decyanation of pergolide intermediate
HU196394B (en) *	1986-06-27	1988-11-28	Richter Gedeon Vegyeszet	Process for preparing 2-halogenated ergoline derivatives

1986
- 1986-04-25 HU HU861719A patent/HU196598B/hu not_active IP Right Cessation
1987
- 1987-03-13 FI FI871128A patent/FI871128A/fi not_active Application Discontinuation
- 1987-04-21 US US07/040,938 patent/US4859682A/en not_active Expired - Fee Related
- 1987-04-22 PT PT84739A patent/PT84739B/pt not_active IP Right Cessation
- 1987-04-23 EG EG238/87A patent/EG18272A/xx active
- 1987-04-23 CN CN198787102944A patent/CN87102944A/zh active Pending
- 1987-04-24 IT IT20271/87A patent/IT1203976B/it active
- 1987-04-24 BE BE8700445A patent/BE1001159A4/fr not_active IP Right Cessation
- 1987-04-24 PL PL1987265357A patent/PL152619B1/pl unknown
- 1987-04-24 GR GR870645A patent/GR870645B/el unknown
- 1987-04-24 NO NO871721A patent/NO165800C/no unknown
- 1987-04-24 CH CH1577/87A patent/CH669791A5/de not_active IP Right Cessation
- 1987-04-24 JP JP62100224A patent/JPS62258379A/ja active Granted
- 1987-04-24 FR FR878705838A patent/FR2597869B1/fr not_active Expired - Fee Related
- 1987-04-24 CS CS872920A patent/CS268534B2/cs unknown
- 1987-04-24 DE DE19873713768 patent/DE3713768A1/de not_active Withdrawn
- 1987-04-24 KR KR1019870003970A patent/KR920008167B1/ko not_active IP Right Cessation
- 1987-04-24 AT AT0102287A patent/AT391472B/de active
- 1987-04-24 DD DD87302104A patent/DD256133A5/de not_active IP Right Cessation
- 1987-04-24 AU AU71945/87A patent/AU592637B2/en not_active Ceased
- 1987-04-24 IN IN326/CAL/87A patent/IN165245B/en unknown
- 1987-04-24 SE SE8701700A patent/SE466401B/sv not_active IP Right Cessation
- 1987-04-24 IL IL82324A patent/IL82324A0/xx not_active IP Right Cessation
- 1987-04-24 SU SU874202410A patent/SU1500161A3/ru active
- 1987-04-24 ES ES8701211A patent/ES2007339A6/es not_active Expired
- 1987-04-24 LU LU86853A patent/LU86853A1/de unknown
- 1987-04-24 ZA ZA872931A patent/ZA872931B/xx unknown
- 1987-04-24 NL NL8700966A patent/NL8700966A/nl not_active Application Discontinuation
- 1987-04-24 DK DK208887A patent/DK208887A/da not_active Application Discontinuation
- 1987-04-27 GB GB8709893A patent/GB2189487B/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
IL82324A0 (en)	1987-10-30
ZA872931B (fr)	1987-10-19
LU86853A1 (de)	1987-08-12
NO871721D0 (no)	1987-04-24
JPS62258379A (ja)	1987-11-10
DK208887A (da)	1987-10-26
GB2189487A (en)	1987-10-28
PL265357A1 (en)	1988-07-21
IT1203976B (it)	1989-02-23
CN87102944A (zh)	1987-11-25
AU592637B2 (en)	1990-01-18
KR870010051A (ko)	1987-11-30
AT391472B (de)	1990-10-10
DD256133A5 (de)	1988-04-27
US4859682A (en)	1989-08-22
PL152619B1 (en)	1991-01-31
DK208887D0 (da)	1987-04-24
IN165245B (fr)	1989-09-09
JPH0462316B2 (fr)	1992-10-05
NO165800C (no)	1991-04-10
SU1500161A3 (ru)	1989-08-07
CS268534B2 (en)	1990-03-14
NO165800B (no)	1991-01-02
SE8701700D0 (sv)	1987-04-24
SE8701700L (sv)	1987-10-26
AU7194587A (en)	1987-10-29
CH669791A5 (fr)	1989-04-14
KR920008167B1 (ko)	1992-09-24
NL8700966A (nl)	1987-11-16
BE1001159A4 (fr)	1989-08-01
PT84739A (en)	1987-05-01
IT8720271A0 (it)	1987-04-24
FI871128A (fi)	1987-10-26
EG18272A (en)	1993-04-30
ES2007339A6 (es)	1989-06-16
CS292087A2 (en)	1989-06-13
ATA102287A (de)	1990-04-15
DE3713768A1 (de)	1987-10-29
GB2189487B (en)	1990-05-23
GB8709893D0 (en)	1987-06-03
NO871721L (no)	1987-10-26
SE466401B (sv)	1992-02-10
GR870645B (en)	1987-08-28
PT84739B (pt)	1989-12-29
HU196598B (en)	1988-12-28
FI871128A0 (fi)	1987-03-13
FR2597869A1 (fr)	1987-10-30

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Legal Events

Date	Code	Title	Description
1994-02-25	ST	Notification of lapse