FR2590256B1 - Carbamoyloxymethylalkylcarbapenemes, leur procede de preparation - Google Patents

Carbamoyloxymethylalkylcarbapenemes, leur procede de preparation

Info

Publication number
FR2590256B1
FR2590256B1 FR868616094A FR8616094A FR2590256B1 FR 2590256 B1 FR2590256 B1 FR 2590256B1 FR 868616094 A FR868616094 A FR 868616094A FR 8616094 A FR8616094 A FR 8616094A FR 2590256 B1 FR2590256 B1 FR 2590256B1
Authority
FR
France
Prior art keywords
carbamoyloxymethylalkylcarbapenemes
preparation process
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR868616094A
Other languages
English (en)
Other versions
FR2590256A1 (fr
Inventor
Shoichiro Uyeo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of FR2590256A1 publication Critical patent/FR2590256A1/fr
Application granted granted Critical
Publication of FR2590256B1 publication Critical patent/FR2590256B1/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FR868616094A 1985-11-19 1986-11-19 Carbamoyloxymethylalkylcarbapenemes, leur procede de preparation Expired FR2590256B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP26073185 1985-11-19

Publications (2)

Publication Number Publication Date
FR2590256A1 FR2590256A1 (fr) 1987-05-22
FR2590256B1 true FR2590256B1 (fr) 1989-12-22

Family

ID=17351968

Family Applications (1)

Application Number Title Priority Date Filing Date
FR868616094A Expired FR2590256B1 (fr) 1985-11-19 1986-11-19 Carbamoyloxymethylalkylcarbapenemes, leur procede de preparation

Country Status (10)

Country Link
JP (1) JPS62201889A (fr)
KR (1) KR870004984A (fr)
AU (1) AU6534786A (fr)
BE (1) BE905784A (fr)
CA (1) CA1283416C (fr)
CH (1) CH671580A5 (fr)
DE (1) DE3639542C2 (fr)
FR (1) FR2590256B1 (fr)
GB (1) GB2183236B (fr)
IT (1) IT1195842B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0292191A1 (fr) * 1987-05-21 1988-11-23 Merck & Co. Inc. Dérivés de 1-alkyl-carbapénème substitués en position 2 par un groupe méthylique substitué
US6143885A (en) * 1997-08-27 2000-11-07 Merck & Co., Inc. Preparation of beta-methyl carbapenem intermediates
WO1999010323A1 (fr) * 1997-08-27 1999-03-04 Merck & Co., Inc. Preparation d'intermediaires de beta-methyl carbapenem

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4260627A (en) * 1978-10-24 1981-04-07 Merck & Co., Inc. 1-, 6- And 2-substituted-1-carba-2-penem-3-carboxylic acids
EP0184844A1 (fr) * 1984-12-13 1986-06-18 Merck & Co. Inc. 1-Méthylcarbapénèmes ayant un substituant, relié par un pont alkylène-thio, en position 2

Also Published As

Publication number Publication date
CH671580A5 (fr) 1989-09-15
DE3639542C2 (de) 1995-07-13
BE905784A (fr) 1987-03-16
GB2183236B (en) 1989-04-12
JPS62201889A (ja) 1987-09-05
IT8667861A0 (it) 1986-11-19
AU6534786A (en) 1987-05-21
GB8627656D0 (en) 1986-12-17
CA1283416C (fr) 1991-04-23
DE3639542A1 (de) 1987-05-21
IT1195842B (it) 1988-10-27
FR2590256A1 (fr) 1987-05-22
GB2183236A (en) 1987-06-03
KR870004984A (ko) 1987-06-04

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Legal Events

Date Code Title Description
ST Notification of lapse